SCOP 1.63: Superfamily c.3.1: FAD/NAD(P)-binding domain

Lineage for Superfamily c.3.1: FAD/NAD(P)-binding domain

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families)

Families:

1. c.3.1.1: C-terminal domain of adrenodoxin reductase-like [51906] (4 proteins)

2. c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (10 proteins)
   C-terminal domain is alpha+beta is common for the family

3. c.3.1.3: Guanine nucleotide dissosiation inhibitor, GDI [51931] (1 protein)
   Similar to FAD-linked reductases in both domains but does not bind FAD

4. c.3.1.4: Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain [51934] (5 proteins)

5. c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (12 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

More info for Superfamily c.3.1: FAD/NAD(P)-binding domain

Timeline for Superfamily c.3.1: FAD/NAD(P)-binding domain:

• Superfamily c.3.1: FAD/NAD(P)-binding domain first appeared (with stable ids) in SCOP 1.55
  
• Superfamily c.3.1: FAD/NAD(P)-binding domain appears in SCOP 1.61
  
• Superfamily c.3.1: FAD/NAD(P)-binding domain appears in SCOP 1.65
  
• Superfamily c.3.1: FAD/NAD(P)-binding domain appears in the current release, SCOPe 2.08