SCOPe 2.08: Protein: Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain

Lineage for Protein: Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)
Family c.2.1.8: CoA-binding domain [51900] (6 proteins)
Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain [51901] (6 species)

Species:

Aeropyrum pernix [TaxId:272557] [225351] (1 PDB entry)
- Domain for 2yv2:
  - Domain d2yv2a1: 2yv2 A:9-128 [207720]
    Other proteins in same PDB: d2yv2a2
    automated match to d1euda1

Escherichia coli [TaxId:562] [51902] (11 PDB entries)

Domains for 1cqi:
1. Domain d1cqia1: 1cqi A:1-121 [30309]
  Other proteins in same PDB: d1cqia2, d1cqib1, d1cqib2, d1cqid2, d1cqie1, d1cqie2
  complexed with adp, coa, mg, po4
2. Domain d1cqid1: 1cqi D:1-121 [30310]
  Other proteins in same PDB: d1cqia2, d1cqib1, d1cqib2, d1cqid2, d1cqie1, d1cqie2
  complexed with adp, coa, mg, po4
Domains for 1cqj:
1. Domain d1cqja1: 1cqj A:1-121 [30305]
  Other proteins in same PDB: d1cqja2, d1cqjb1, d1cqjb2, d1cqjd2, d1cqje1, d1cqje2
  complexed with coa, po4
2. Domain d1cqjd1: 1cqj D:1-121 [30306]
  Other proteins in same PDB: d1cqja2, d1cqjb1, d1cqjb2, d1cqjd2, d1cqje1, d1cqje2
  complexed with coa, po4
Domains for 1jkj:
1. Domain d1jkja1: 1jkj A:1-121 [66800]
  Other proteins in same PDB: d1jkja2, d1jkjb1, d1jkjb2, d1jkjd2, d1jkje1, d1jkje2
  complexed with coa, gol, po4, so4
2. Domain d1jkjd1: 1jkj D:1-121 [66804]
  Other proteins in same PDB: d1jkja2, d1jkjb1, d1jkjb2, d1jkjd2, d1jkje1, d1jkje2
  complexed with coa, gol, po4, so4
Domains for 1jll:
1. Domain d1jlla1: 1jll A:1-121 [66851]
  Other proteins in same PDB: d1jlla2, d1jllb1, d1jllb2, d1jlld2, d1jlle1, d1jlle2
  complexed with coa, po4, so4; mutant
2. Domain d1jlld1: 1jll D:1-121 [66855]
  Other proteins in same PDB: d1jlla2, d1jllb1, d1jllb2, d1jlld2, d1jlle1, d1jlle2
  complexed with coa, po4, so4; mutant
Domains for 1scu:
1. Domain d1scua1: 1scu A:1-121 [30307]
  Other proteins in same PDB: d1scua2, d1scub1, d1scub2, d1scud2, d1scue1, d1scue2
  complexed with coa
2. Domain d1scud1: 1scu D:1-121 [30308]
  Other proteins in same PDB: d1scua2, d1scub1, d1scub2, d1scud2, d1scue1, d1scue2
  complexed with coa
Domains for 2nu6:
1. Domain d2nu6a1: 2nu6 A:1-121 [148396]
  Other proteins in same PDB: d2nu6a2, d2nu6b1, d2nu6b2, d2nu6d2, d2nu6e1, d2nu6e2
  automated match to d1jkja1
  complexed with coa, so4; mutant
2. Domain d2nu6d1: 2nu6 D:1-121 [148400]
  Other proteins in same PDB: d2nu6a2, d2nu6b1, d2nu6b2, d2nu6d2, d2nu6e1, d2nu6e2
  automated match to d1jkja1
  complexed with coa, so4; mutant
Domains for 2nu7:
1. Domain d2nu7a1: 2nu7 A:1-121 [148404]
  Other proteins in same PDB: d2nu7a2, d2nu7b1, d2nu7b2, d2nu7d2, d2nu7e1, d2nu7e2
  automated match to d1jkja1
  complexed with coa, po4, so4; mutant
2. Domain d2nu7d1: 2nu7 D:1-121 [148408]
  Other proteins in same PDB: d2nu7a2, d2nu7b1, d2nu7b2, d2nu7d2, d2nu7e1, d2nu7e2
  automated match to d1jkja1
  complexed with coa, po4, so4; mutant
Domains for 2nu8:
1. Domain d2nu8a1: 2nu8 A:1-121 [148412]
  Other proteins in same PDB: d2nu8a2, d2nu8b1, d2nu8b2, d2nu8d2, d2nu8e1, d2nu8e2
  automated match to d1jkja1
  complexed with coa, gol, po4, so4; mutant
2. Domain d2nu8d1: 2nu8 D:1-121 [148416]
  Other proteins in same PDB: d2nu8a2, d2nu8b1, d2nu8b2, d2nu8d2, d2nu8e1, d2nu8e2
  automated match to d1jkja1
  complexed with coa, gol, po4, so4; mutant

Domains for 2nu9:

Domain d2nu9a1: 2nu9 A:1-121 [148420]
Other proteins in same PDB: d2nu9a2, d2nu9b1, d2nu9b2, d2nu9d2, d2nu9e1, d2nu9e2, d2nu9f2, d2nu9g1, d2nu9g2, d2nu9h2, d2nu9i1, d2nu9i2
automated match to d1jkja1
complexed with coa, so4; mutant

Domain d2nu9d1: 2nu9 D:1-121 [148424]
Other proteins in same PDB: d2nu9a2, d2nu9b1, d2nu9b2, d2nu9d2, d2nu9e1, d2nu9e2, d2nu9f2, d2nu9g1, d2nu9g2, d2nu9h2, d2nu9i1, d2nu9i2
automated match to d1jkja1
complexed with coa, so4; mutant

Domain d2nu9f1: 2nu9 F:1-121 [148428]
Other proteins in same PDB: d2nu9a2, d2nu9b1, d2nu9b2, d2nu9d2, d2nu9e1, d2nu9e2, d2nu9f2, d2nu9g1, d2nu9g2, d2nu9h2, d2nu9i1, d2nu9i2
automated match to d1jkja1
complexed with coa, so4; mutant

Domain d2nu9h1: 2nu9 H:1-121 [148432]
Other proteins in same PDB: d2nu9a2, d2nu9b1, d2nu9b2, d2nu9d2, d2nu9e1, d2nu9e2, d2nu9f2, d2nu9g1, d2nu9g2, d2nu9h2, d2nu9i1, d2nu9i2
automated match to d1jkja1
complexed with coa, so4; mutant

Domains for 2nua:
1. Domain d2nuaa1: 2nua A:1-121 [148436]
  Other proteins in same PDB: d2nuaa2, d2nuab1, d2nuab2, d2nuad2, d2nuae1, d2nuae2
  automated match to d1jkja1
  complexed with coa, po4, so4; mutant
2. Domain d2nuad1: 2nua D:1-121 [148440]
  Other proteins in same PDB: d2nuaa2, d2nuab1, d2nuab2, d2nuad2, d2nuae1, d2nuae2
  automated match to d1jkja1
  complexed with coa, po4, so4; mutant
Domains for 2scu:
1. Domain d2scua1: 2scu A:1-121 [30303]
  Other proteins in same PDB: d2scua2, d2scub1, d2scub2, d2scud2, d2scue1, d2scue2
  complexed with coa, so4
2. Domain d2scud1: 2scu D:1-121 [30304]
  Other proteins in same PDB: d2scua2, d2scub1, d2scub2, d2scud2, d2scue1, d2scue2
  complexed with coa, so4

Human (Homo sapiens) [TaxId:9606] [350887] (2 PDB entries)
1. Domain for 6g4q:
  - Domain d6g4qa1: 6g4q A:42-170 [350888]
    Other proteins in same PDB: d6g4qa2, d6g4qa3
    automated match to d1euda1
    complexed with edo, nep
2. Domain for 6wcv:
  - Domain d6wcva1: 6wcv A:2-130 [389508]
    Other proteins in same PDB: d6wcva2, d6wcva3, d6wcvb1, d6wcvb2
    automated match to d1euda1
    complexed with tuy
Methanocaldococcus jannaschii [TaxId:243232] [225349] (1 PDB entry)
- Domain for 2yv1:
  - Domain d2yv1a1: 2yv1 A:7-127 [207718]
    Other proteins in same PDB: d2yv1a2
    automated match to d1jkja1
Pig (Sus scrofa) [TaxId:9823] [51903] (13 PDB entries)
1. Domain for 1euc:
  - Domain d1euca1: 1euc A:1-130 [30311]
    Other proteins in same PDB: d1euca2, d1eucb1, d1eucb2, d1eucb3
    complexed with po4, so4, zn
2. Domain for 1eud:
  - Domain d1euda1: 1eud A:1-130 [30312]
    Other proteins in same PDB: d1euda2, d1eudb1, d1eudb2, d1eudb3
    complexed with so4
3. Domain for 2fp4:
  - Domain d2fp4a1: 2fp4 A:3-130 [133895]
    Other proteins in same PDB: d2fp4a2, d2fp4a3, d2fp4b1, d2fp4b2
    automated match to d1euda1
    complexed with gtp, k, mg
4. Domain for 2fpg:
  - Domain d2fpga1: 2fpg A:3-130 [133900]
    Other proteins in same PDB: d2fpga2, d2fpga3, d2fpgb1, d2fpgb2
    automated match to d1euda1
    complexed with gdp, k, po4
5. Domain for 2fpi:
  - Domain d2fpia1: 2fpi A:3-130 [133904]
    Other proteins in same PDB: d2fpia2, d2fpia3, d2fpib1, d2fpib2
    automated match to d1euda1
    complexed with so4
6. Domain for 2fpp:
  - Domain d2fppa1: 2fpp A:3-130 [133915]
    Other proteins in same PDB: d2fppa2, d2fppa3, d2fppb1, d2fppb2
    automated match to d1euda1
    complexed with cl, so4
7. Domain for 4xx0:
  - Domain d4xx0a1: 4xx0 A:2-130 [276060]
    Other proteins in same PDB: d4xx0a2, d4xx0b1, d4xx0b2
    automated match to d1euda1
    complexed with coa, gol, po4, so4
8. Domain for 5cae:
  - Domain d5caea1: 5cae A:2-130 [318908]
    Other proteins in same PDB: d5caea2, d5caeb1, d5caeb2
    automated match to d1euda1
    complexed with cl, coa, gol, mg, po4, sin
9. Domain for 6xru:
  - Domain d6xrua1: 6xru A:2-130 [401145]
    Other proteins in same PDB: d6xrua2, d6xrua3, d6xrub1, d6xrub2
    automated match to d1euda1
    complexed with dca, edo, gol, mg, po4, sin
10. Domain for 7jfp:
  - Domain d7jfpa1: 7jfp A:2-130 [398969]
    Other proteins in same PDB: d7jfpa2, d7jfpb1, d7jfpb2
    automated match to d1euda1
    complexed with gdp, gol, mg
11. Domains for 7jj0:
  1. Domain d7jj0a1: 7jj0 A:2-130 [398981]
    Other proteins in same PDB: d7jj0a2, d7jj0b1, d7jj0b2, d7jj0c2, d7jj0d1, d7jj0d2
    automated match to d1euda1
    complexed with gcp, mg
  2. Domain d7jj0c1: 7jj0 C:2-130 [398988]
    Other proteins in same PDB: d7jj0a2, d7jj0b1, d7jj0b2, d7jj0c2, d7jj0d1, d7jj0d2
    automated match to d1euda1
    complexed with gcp, mg
12. Domain for 7jkr:
  - Domain d7jkra1: 7jkr A:2-130 [398975]
    Other proteins in same PDB: d7jkra2, d7jkrb1, d7jkrb2
    automated match to d1euda1
    complexed with gnp, gol, mg
13. Domains for 7jmk:
  1. Domain d7jmka1: 7jmk A:2-130 [399008]
    Other proteins in same PDB: d7jmka2, d7jmkb1, d7jmkb2, d7jmkc2, d7jmkd1, d7jmkd2
    automated match to d1euda1
    complexed with gdp, mg
  2. Domain d7jmkc1: 7jmk C:2-130 [399012]
    Other proteins in same PDB: d7jmka2, d7jmkb1, d7jmkb2, d7jmkc2, d7jmkd1, d7jmkd2
    automated match to d1euda1
    complexed with gdp, mg
Thermus thermophilus [TaxId:274] [89541] (1 PDB entry)
- Domain for 1oi7:
  - Domain d1oi7a1: 1oi7 A:1-121 [87049]
    Other proteins in same PDB: d1oi7a2
    alpha-chain only

More info for Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain from c.2.1.8: CoA-binding domain

Timeline for Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain from c.2.1.8: CoA-binding domain:

Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain from c.2.1.8: CoA-binding domain first appeared (with stable ids) in SCOP 1.55, called Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain from c.2.1.8: Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain
Protein Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain from c.2.1.8: CoA-binding domain appears in SCOPe 2.07