SCOPe 2.08: Family c.2.1.8: CoA-binding domain

Lineage for Family c.2.1.8: CoA-binding domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.8: CoA-binding domain [51900] (6 proteins)

Proteins:

1. Acetate-CoA ligase alpha chain, AcdA, N-terminal domain [141936] (1 species)

   • Species Pyrococcus horikoshii [TaxId:53953] [141937] (1 PDB entry)
     Uniprot O58493 1-129

2. Hypothetical protein PF0725 [141938] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [141939] (1 PDB entry)
     Uniprot Q8U2V3 6-121

3. Hypothetical protein PH1109 [141934] (1 species)

   • Species Pyrococcus horikoshii [TaxId:53953] [141935] (4 PDB entries)
     Uniprot O58836 1-142

4. Hypothetical protein TT1466 [89542] (1 species)
   putative CoA-binding protein

   • Species Thermus thermophilus [TaxId:274] [89543] (2 PDB entries)

5. Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain [51901] (6 species)

   1. Species Aeropyrum pernix [TaxId:272557] [225351] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [51902] (11 PDB entries)

   3. Species Human (Homo sapiens) [TaxId:9606] [350887] (2 PDB entries)

   4. Species Methanocaldococcus jannaschii [TaxId:243232] [225349] (1 PDB entry)

   5. Species Pig (Sus scrofa) [TaxId:9823] [51903] (13 PDB entries)

   6. Species Thermus thermophilus [TaxId:274] [89541] (1 PDB entry)

6. automated matches [191286] (1 species)
   not a true protein

   • Species Escherichia coli [TaxId:562] [189926] (2 PDB entries)

More info for Family c.2.1.8: CoA-binding domain

Timeline for Family c.2.1.8: CoA-binding domain:

• Family c.2.1.8: CoA-binding domain first appeared (with stable ids) in SCOP 1.55, called Family c.2.1.8: Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain
  
• Family c.2.1.8: CoA-binding domain appears in SCOPe 2.07