Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2093723Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 protein domains)
    extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site
  6. 2093868Protein Methylenetetrahydrofolate dehydrogenase/cyclohydrolase [51894] (3 species)
    the two-domain organization is similar to that of aminoacid dehydrogenases, but both domains are truncated
  7. 2093874Species Human (Homo sapiens) [TaxId:9606] [51895] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1a4i:
    1. 2093875Domain d1a4ia1: 1a4i A:127-296 [30278]
      Other proteins in same PDB: d1a4ia2, d1a4ib2
      complexed with ndp
    2. 2093876Domain d1a4ib1: 1a4i B:127-296 [30279]
      Other proteins in same PDB: d1a4ia2, d1a4ib2
      complexed with ndp
  2. Domain(s) for 1dia:
    1. 2093879Domain d1diaa1: 1dia A:127-296 [30280]
      Other proteins in same PDB: d1diaa2, d1diab2
      complexed with l24, nap
    2. 2093880Domain d1diab1: 1dia B:1127-1296 [30281]
      Other proteins in same PDB: d1diaa2, d1diab2
      complexed with l24, nap
  3. Domain(s) for 1dib:
    1. 2093881Domain d1diba1: 1dib A:127-296 [30284]
      Other proteins in same PDB: d1diba2, d1dibb2
      complexed with l34, nap
    2. 2093882Domain d1dibb1: 1dib B:1127-1296 [30285]
      Other proteins in same PDB: d1diba2, d1dibb2
      complexed with l34, nap
  4. Domain(s) for 1dig:
    1. 2093877Domain d1diga1: 1dig A:127-296 [30282]
      Other proteins in same PDB: d1diga2, d1digb2
      complexed with act, l37, nap
    2. 2093878Domain d1digb1: 1dig B:1127-1296 [30283]
      Other proteins in same PDB: d1diga2, d1digb2
      complexed with act, l37, nap

More info for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.7 Methylenetetrahydrofolate dehydrogenase/cyclohydrolase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.7 Methylenetetrahydrofolate dehydrogenase/cyclohydrolase: