SCOPe 2.07: Protein: Phenylalanine dehydrogenase

Lineage for Protein: Phenylalanine dehydrogenase

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

Protein Phenylalanine dehydrogenase [51892] (1 species)

Species:

Rhodococcus sp., M4 [TaxId:1831] [51893] (4 PDB entries)
1. Domains for 1bw9:
  1. Domain d1bw9a1: 1bw9 A:149-350 [30274]
    Other proteins in same PDB: d1bw9a2, d1bw9b2
    complexed with edo, ipa, k, na, nad, po4, ppy
  2. Domain d1bw9b1: 1bw9 B:549-747 [30275]
    Other proteins in same PDB: d1bw9a2, d1bw9b2
    complexed with edo, ipa, k, na, nad, po4, ppy
2. Domains for 1bxg:
  1. Domain d1bxga1: 1bxg A:149-349 [30276]
    Other proteins in same PDB: d1bxga2, d1bxgb2
    complexed with hci, k, nad, po4
  2. Domain d1bxgb1: 1bxg B:549-747 [30277]
    Other proteins in same PDB: d1bxga2, d1bxgb2
    complexed with hci, k, nad, po4
3. Domains for 1c1d:
  1. Domain d1c1da1: 1c1d A:149-349 [30270]
    Other proteins in same PDB: d1c1da2, d1c1db2
    complexed with ipa, k, na, nai, phe, po4
  2. Domain d1c1db1: 1c1d B:149-348 [30271]
    Other proteins in same PDB: d1c1da2, d1c1db2
    complexed with ipa, k, na, nai, phe, po4
4. Domains for 1c1x:
  1. Domain d1c1xa1: 1c1x A:149-348 [30272]
    Other proteins in same PDB: d1c1xa2, d1c1xb2
    complexed with hfa, ipa, k, na, nad, po4
  2. Domain d1c1xb1: 1c1x B:149-347 [30273]
    Other proteins in same PDB: d1c1xa2, d1c1xb2
    complexed with hfa, ipa, k, na, nad, po4

More info for Protein Phenylalanine dehydrogenase from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain

Timeline for Protein Phenylalanine dehydrogenase from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain:

Protein Phenylalanine dehydrogenase from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain first appeared (with stable ids) in SCOP 1.55, called Protein Phenylalanine dehydrogenase from c.2.1.7: Amino-acid dehydrogenase-like, C-terminal domain
Protein Phenylalanine dehydrogenase from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain appears in SCOPe 2.06
Protein Phenylalanine dehydrogenase from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain appears in the current release, SCOPe 2.08