Lineage for Protein: Lactate dehydrogenase

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 685975Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 685976Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 687902Family c.2.1.5: LDH N-terminal domain-like [51848] (8 proteins)
  6. 687941Protein Lactate dehydrogenase [51859] (14 species)

Species:

  1. 687942Bacillus stearothermophilus [TaxId:1422] [51864] (3 PDB entries)
    1. Domains for 1ldb:
      1. 687951Domain d1ldba1: 1ldb A:15-162 [30174]
        Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2
        complexed with so4
      2. 687952Domain d1ldbb1: 1ldb B:15-162 [118523]
        Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2
        duplicate of 1LDB 15-162
        complexed with so4
      3. 687953Domain d1ldbc1: 1ldb C:15-162 [118525]
        Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2
        duplicate of 1LDB 15-162
        complexed with so4
      4. 687954Domain d1ldbd1: 1ldb D:15-162 [118527]
        Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2
        duplicate of 1LDB 15-162
        complexed with so4
    2. Domains for 1ldn:
      1. 687943Domain d1ldna1: 1ldn A:15-162 [30166]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      2. 687944Domain d1ldnb1: 1ldn B:15-162 [30167]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      3. 687945Domain d1ldnc1: 1ldn C:15-162 [30168]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      4. 687946Domain d1ldnd1: 1ldn D:15-162 [30169]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      5. 687947Domain d1ldne1: 1ldn E:15-162 [30170]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      6. 687948Domain d1ldnf1: 1ldn F:15-162 [30171]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      7. 687949Domain d1ldng1: 1ldn G:15-162 [30172]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      8. 687950Domain d1ldnh1: 1ldn H:15-162 [30173]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
        complexed with fbp, nad, oxm
    3. Domains for 2ldb:
      1. 687955Domain d2ldba1: 2ldb A:15-162 [30175]
        Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2
        complexed with fbp, nad, so4
      2. 687956Domain d2ldbb1: 2ldb B:15-162 [118636]
        Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2
        duplicate of 2LDB 15-162
        complexed with fbp, nad, so4
      3. 687957Domain d2ldbc1: 2ldb C:15-162 [118638]
        Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2
        duplicate of 2LDB 15-162
        complexed with fbp, nad, so4
      4. 687958Domain d2ldbd1: 2ldb D:15-162 [118640]
        Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2
        duplicate of 2LDB 15-162
        complexed with fbp, nad, so4
  2. 687959Bifidobacterium longum, strain am101-2 [TaxId:216816] [51866] (2 PDB entries)
    1. Domains for 1lld:
      1. 687960Domain d1llda1: 1lld A:7-149 [30177]
        Other proteins in same PDB: d1llda2, d1lldb2
      2. 687961Domain d1lldb1: 1lld B:7-149 [30178]
        Other proteins in same PDB: d1llda2, d1lldb2
        complexed with nad; mutant
    2. Domains for 1lth:
      1. 687962Domain d1lthr1: 1lth R:7-149 [30179]
        Other proteins in same PDB: d1lthr2, d1ltht2
      2. 687963Domain d1ltht1: 1lth T:7-149 [30180]
        Other proteins in same PDB: d1lthr2, d1ltht2
        complexed with fbp, nad, oxm; mutant
  3. 687964Clostridium thermocellum [TaxId:1515] [117432] (1 PDB entry)
  4. 687966Dogfish (Squalus acanthias) [TaxId:7797] [51862] (3 PDB entries)
    1. Domain for 1ldm:
    2. Domain for 6ldh:
    3. Domain for 8ldh:
  5. 687970Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [63939] (2 PDB entries)
    1. Domains for 1i0z:
      1. 687971Domain d1i0za1: 1i0z A:1-160 [61495]
        Other proteins in same PDB: d1i0za2, d1i0zb2
      2. 687972Domain d1i0zb1: 1i0z B:1-160 [61497]
        Other proteins in same PDB: d1i0za2, d1i0zb2
        complexed with nai, oxm
    2. Domains for 1t2f:
      1. 687973Domain d1t2fa1: 1t2f A:1-160 [99088]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      2. 687974Domain d1t2fb1: 1t2f B:1-160 [99090]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      3. 687975Domain d1t2fc1: 1t2f C:1-160 [99092]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      4. 687976Domain d1t2fd1: 1t2f D:1-160 [99094]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
        complexed with nad, oxq; mutant
  6. 687977Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (1 PDB entry)
  7. 687986Lactobacillus casei [TaxId:1582] [51865] (1 PDB entry)
  8. 687988Lactobacillus pentosus [TaxId:1589] [69418] (1 PDB entry)
  9. 687993Malaria parasite (Plasmodium falciparum) [TaxId:5833] [51863] (9 PDB entries)
    1. Domain for 1ceq:
    2. Domain for 1cet:
    3. Domain for 1ldg:
    4. Domain for 1t24:
    5. Domain for 1t25:
    6. Domain for 1t26:
    7. Domain for 1t2c:
    8. Domain for 1t2d:
    9. Domain for 1t2e:
  10. 688003Mouse (Mus musculus) [TaxId:10090] [51861] (1 PDB entry)
  11. 688008Pig (Sus scrofa) [TaxId:9823] [51860] (3 PDB entries)
    1. Domain for 5ldh:
    2. Domains for 9ldb:
      1. 688011Domain d9ldba1: 9ldb A:1-162 [30156]
        Other proteins in same PDB: d9ldba2, d9ldbb2
      2. 688012Domain d9ldbb1: 9ldb B:1-162 [30157]
        Other proteins in same PDB: d9ldba2, d9ldbb2
        complexed with nad, oxm, so4
    3. Domains for 9ldt:
      1. 688009Domain d9ldta1: 9ldt A:1-162 [30154]
        Other proteins in same PDB: d9ldta2, d9ldtb2
      2. 688010Domain d9ldtb1: 9ldt B:1-162 [30155]
        Other proteins in same PDB: d9ldta2, d9ldtb2
        complexed with nad, oxm, so4
  12. 688014Plasmodium berghei [TaxId:5821] [102165] (7 PDB entries)
    1. Domains for 1oc4:
      1. 688021Domain d1oc4a1: 1oc4 A:18-163 [92770]
        Other proteins in same PDB: d1oc4a2, d1oc4b2
      2. 688022Domain d1oc4b1: 1oc4 B:18-163 [92772]
        Other proteins in same PDB: d1oc4a2, d1oc4b2
        complexed with gol, nad, oxm
    2. Domain for 1u4o:
    3. Domain for 1u4s:
    4. Domain for 1u5a:
    5. Domain for 1u5c:
    6. Domain for 1xiv:
    7. Domain for 2a94:
  13. 688023Thermotoga maritima [TaxId:2336] [51867] (1 PDB entry)
  14. 688025Toxoplasma gondii [TaxId:5811] [102166] (4 PDB entries)
    1. Domain for 1pze:
    2. Domains for 1pzf:
      1. 688035Domain d1pzfa1: 1pzf A:14-163 [95417]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      2. 688036Domain d1pzfb1: 1pzf B:14-163 [95419]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      3. 688037Domain d1pzfc1: 1pzf C:14-163 [95421]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      4. 688038Domain d1pzfd1: 1pzf D:14-163 [95423]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
        complexed with a3d, oxl
    3. Domains for 1pzg:
      1. 688027Domain d1pzga1: 1pzg A:14-163 [95425]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      2. 688028Domain d1pzgb1: 1pzg B:14-163 [95427]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      3. 688029Domain d1pzgc1: 1pzg C:15-163 [95429]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      4. 688030Domain d1pzgd1: 1pzg D:14-163 [95431]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
        complexed with a3d, so4
    4. Domains for 1pzh:
      1. 688031Domain d1pzha1: 1pzh A:14-163 [95433]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      2. 688032Domain d1pzhb1: 1pzh B:14-163 [95435]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      3. 688033Domain d1pzhc1: 1pzh C:14-163 [95437]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      4. 688034Domain d1pzhd1: 1pzh D:14-163 [95439]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
        complexed with nad, oxl

More info for Protein Lactate dehydrogenase from c.2.1.5: LDH N-terminal domain-like

Timeline for Protein Lactate dehydrogenase from c.2.1.5: LDH N-terminal domain-like: