![]() | Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
![]() | Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
![]() | Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) ![]() |
![]() | Family c.2.1.5: LDH N-terminal domain-like [51848] (8 proteins) |
![]() | Protein Lactate dehydrogenase [51859] (14 species) |
![]() | Bacillus stearothermophilus [TaxId:1422] [51864] (3 PDB entries) |
![]() | Domain d1ldba1: 1ldb A:15-162 [30174] Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2 complexed with so4 |
![]() | Domain d1ldbb1: 1ldb B:15-162 [118523] Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2 duplicate of 1LDB 15-162 complexed with so4 |
![]() | Domain d1ldbc1: 1ldb C:15-162 [118525] Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2 duplicate of 1LDB 15-162 complexed with so4 |
![]() | Domain d1ldbd1: 1ldb D:15-162 [118527] Other proteins in same PDB: d1ldba2, d1ldbb2, d1ldbc2, d1ldbd2 duplicate of 1LDB 15-162 complexed with so4 |
![]() | Domain d1ldna1: 1ldn A:15-162 [30166] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldnb1: 1ldn B:15-162 [30167] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldnc1: 1ldn C:15-162 [30168] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldnd1: 1ldn D:15-162 [30169] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldne1: 1ldn E:15-162 [30170] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldnf1: 1ldn F:15-162 [30171] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldng1: 1ldn G:15-162 [30172] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 |
![]() | Domain d1ldnh1: 1ldn H:15-162 [30173] Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2 complexed with fbp, nad, oxm |
![]() | Domain d2ldba1: 2ldb A:15-162 [30175] Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2 complexed with fbp, nad, so4 |
![]() | Domain d2ldbb1: 2ldb B:15-162 [118636] Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2 duplicate of 2LDB 15-162 complexed with fbp, nad, so4 |
![]() | Domain d2ldbc1: 2ldb C:15-162 [118638] Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2 duplicate of 2LDB 15-162 complexed with fbp, nad, so4 |
![]() | Domain d2ldbd1: 2ldb D:15-162 [118640] Other proteins in same PDB: d2ldba2, d2ldbb2, d2ldbc2, d2ldbd2 duplicate of 2LDB 15-162 complexed with fbp, nad, so4 |
![]() | Bifidobacterium longum, strain am101-2 [TaxId:216816] [51866] (2 PDB entries) |
![]() | Domain d1llda1: 1lld A:7-149 [30177] Other proteins in same PDB: d1llda2, d1lldb2 |
![]() | Domain d1lldb1: 1lld B:7-149 [30178] Other proteins in same PDB: d1llda2, d1lldb2 complexed with nad; mutant |
![]() | Domain d1lthr1: 1lth R:7-149 [30179] Other proteins in same PDB: d1lthr2, d1ltht2 |
![]() | Domain d1ltht1: 1lth T:7-149 [30180] Other proteins in same PDB: d1lthr2, d1ltht2 complexed with fbp, nad, oxm; mutant |
![]() | Clostridium thermocellum [TaxId:1515] [117432] (1 PDB entry) |
![]() | Domain d1y6ja1: 1y6j A:7-148 [116507] Other proteins in same PDB: d1y6ja2 Structural genomics target |
![]() | Dogfish (Squalus acanthias) [TaxId:7797] [51862] (3 PDB entries) |
![]() | Domain d1ldma1: 1ldm A:1-160 [30160] Other proteins in same PDB: d1ldma2 complexed with nad, oxm |
![]() | Domain d6ldha1: 6ldh A:1-160 [30161] Other proteins in same PDB: d6ldha2 complexed with so4 |
![]() | Domain d8ldha1: 8ldh A:1-160 [30162] Other proteins in same PDB: d8ldha2 complexed with cit |
![]() | Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [63939] (2 PDB entries) |
![]() | Domain d1i0za1: 1i0z A:1-160 [61495] Other proteins in same PDB: d1i0za2, d1i0zb2 |
![]() | Domain d1i0zb1: 1i0z B:1-160 [61497] Other proteins in same PDB: d1i0za2, d1i0zb2 complexed with nai, oxm |
![]() | Domain d1t2fa1: 1t2f A:1-160 [99088] Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2 |
![]() | Domain d1t2fb1: 1t2f B:1-160 [99090] Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2 |
![]() | Domain d1t2fc1: 1t2f C:1-160 [99092] Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2 |
![]() | Domain d1t2fd1: 1t2f D:1-160 [99094] Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2 complexed with nad, oxq; mutant |
![]() | Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (1 PDB entry) |
![]() | Domain d1i10a1: 1i10 A:1-159 [61499] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10b1: 1i10 B:1-159 [61501] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10c1: 1i10 C:1-159 [61503] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10d1: 1i10 D:1-159 [61505] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10e1: 1i10 E:1-159 [61507] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10f1: 1i10 F:1-159 [61509] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10g1: 1i10 G:1-159 [61511] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 |
![]() | Domain d1i10h1: 1i10 H:1-159 [61513] Other proteins in same PDB: d1i10a2, d1i10b2, d1i10c2, d1i10d2, d1i10e2, d1i10f2, d1i10g2, d1i10h2 complexed with act, nai, oxm |
![]() | Lactobacillus casei [TaxId:1582] [51865] (1 PDB entry) |
![]() | Domain d1llca1: 1llc A:13-164 [30176] Other proteins in same PDB: d1llca2 complexed with fbp, so4 |
![]() | Lactobacillus pentosus [TaxId:1589] [69418] (1 PDB entry) |
![]() | Domain d1ez4a1: 1ez4 A:16-162 [64917] Other proteins in same PDB: d1ez4a2, d1ez4b2, d1ez4c2, d1ez4d2 |
![]() | Domain d1ez4b1: 1ez4 B:16-162 [64919] Other proteins in same PDB: d1ez4a2, d1ez4b2, d1ez4c2, d1ez4d2 |
![]() | Domain d1ez4c1: 1ez4 C:16-162 [64921] Other proteins in same PDB: d1ez4a2, d1ez4b2, d1ez4c2, d1ez4d2 |
![]() | Domain d1ez4d1: 1ez4 D:16-162 [64923] Other proteins in same PDB: d1ez4a2, d1ez4b2, d1ez4c2, d1ez4d2 complexed with nad |
![]() | Malaria parasite (Plasmodium falciparum) [TaxId:5833] [51863] (9 PDB entries) |
![]() | Domain d1ceqa1: 1ceq A:19-163 [30163] Other proteins in same PDB: d1ceqa2 |
![]() | Domain d1ceta1: 1cet A:18-163 [30164] Other proteins in same PDB: d1ceta2 complexed with clq |
![]() | Domain d1ldga1: 1ldg A:18-163 [30165] Other proteins in same PDB: d1ldga2 complexed with nad, oxm |
![]() | Domain d1t24a1: 1t24 A:18-163 [99069] Other proteins in same PDB: d1t24a2 complexed with gol, nad, oxq |
![]() | Domain d1t25a1: 1t25 A:18-163 [99071] Other proteins in same PDB: d1t25a2 complexed with gag, gol, nai |
![]() | Domain d1t26a1: 1t26 A:19-163 [99073] Other proteins in same PDB: d1t26a2 complexed with gbd, nai |
![]() | Domain d1t2ca1: 1t2c A:18-163 [99082] Other proteins in same PDB: d1t2ca2 complexed with gol, nai |
![]() | Domain d1t2da1: 1t2d A:1-150 [99084] Other proteins in same PDB: d1t2da2 complexed with gol, nad, oxl |
![]() | Domain d1t2ea1: 1t2e A:18-163 [99086] Other proteins in same PDB: d1t2ea2 complexed with gol, nai, oxm; mutant |
![]() | Mouse (Mus musculus) [TaxId:10090] [51861] (1 PDB entry) |
![]() | Domain d2ldxa1: 2ldx A:1-159 [30159] Other proteins in same PDB: d2ldxa2, d2ldxb2, d2ldxc2, d2ldxd2 |
![]() | Domain d2ldxb1: 2ldx B:1-159 [118642] Other proteins in same PDB: d2ldxa2, d2ldxb2, d2ldxc2, d2ldxd2 duplicate of 2LDX 1-159 |
![]() | Domain d2ldxc1: 2ldx C:1-159 [118644] Other proteins in same PDB: d2ldxa2, d2ldxb2, d2ldxc2, d2ldxd2 duplicate of 2LDX 1-159 |
![]() | Domain d2ldxd1: 2ldx D:1-159 [118646] Other proteins in same PDB: d2ldxa2, d2ldxb2, d2ldxc2, d2ldxd2 duplicate of 2LDX 1-159 |
![]() | Pig (Sus scrofa) [TaxId:9823] [51860] (3 PDB entries) |
![]() | Domain d5ldha1: 5ldh A:1-162 [30158] Other proteins in same PDB: d5ldha2 complexed with cit, nal |
![]() | Domain d9ldba1: 9ldb A:1-162 [30156] Other proteins in same PDB: d9ldba2, d9ldbb2 |
![]() | Domain d9ldbb1: 9ldb B:1-162 [30157] Other proteins in same PDB: d9ldba2, d9ldbb2 complexed with nad, oxm, so4 |
![]() | Domain d9ldta1: 9ldt A:1-162 [30154] Other proteins in same PDB: d9ldta2, d9ldtb2 |
![]() | Domain d9ldtb1: 9ldt B:1-162 [30155] Other proteins in same PDB: d9ldta2, d9ldtb2 complexed with nad, oxm, so4 |
![]() | Plasmodium berghei [TaxId:5821] [102165] (7 PDB entries) |
![]() | Domain d1oc4a1: 1oc4 A:18-163 [92770] Other proteins in same PDB: d1oc4a2, d1oc4b2 |
![]() | Domain d1oc4b1: 1oc4 B:18-163 [92772] Other proteins in same PDB: d1oc4a2, d1oc4b2 complexed with gol, nad, oxm |
![]() | Domain d1u4oa1: 1u4o A:18-163 [119527] Other proteins in same PDB: d1u4oa2 automatically matched to d1oc4a1 complexed with mpd, ndd |
![]() | Domain d1u4sa1: 1u4s A:18-163 [119529] Other proteins in same PDB: d1u4sa2 automatically matched to d1oc4a1 complexed with bih |
![]() | Domain d1u5aa1: 1u5a A:18-163 [119532] Other proteins in same PDB: d1u5aa2 automatically matched to d1oc4a1 complexed with bik |
![]() | Domain d1u5ca1: 1u5c A:18-163 [119534] Other proteins in same PDB: d1u5ca2 automatically matched to d1oc4a1 complexed with bik, nad |
![]() | Domain d1xiva1: 1xiv A:18-163 [122018] Other proteins in same PDB: d1xiva2 automatically matched to d1oc4a1 complexed with gol, rb2 |
![]() | Domain d2a94a1: 2a94 A:18-163 [126423] Other proteins in same PDB: d2a94a2 automatically matched to d1oc4a1 complexed with ap0 |
![]() | Thermotoga maritima [TaxId:2336] [51867] (1 PDB entry) |
![]() | Domain d1a5za1: 1a5z A:22-163 [30181] Other proteins in same PDB: d1a5za2 complexed with cd, fbp, nad, oxm |
![]() | Toxoplasma gondii [TaxId:5811] [102166] (4 PDB entries) |
![]() | Domain d1pzea1: 1pze A:14-163 [95415] Other proteins in same PDB: d1pzea2 |
![]() | Domain d1pzfa1: 1pzf A:14-163 [95417] Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2 |
![]() | Domain d1pzfb1: 1pzf B:14-163 [95419] Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2 |
![]() | Domain d1pzfc1: 1pzf C:14-163 [95421] Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2 |
![]() | Domain d1pzfd1: 1pzf D:14-163 [95423] Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2 complexed with a3d, oxl |
![]() | Domain d1pzga1: 1pzg A:14-163 [95425] Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2 |
![]() | Domain d1pzgb1: 1pzg B:14-163 [95427] Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2 |
![]() | Domain d1pzgc1: 1pzg C:15-163 [95429] Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2 |
![]() | Domain d1pzgd1: 1pzg D:14-163 [95431] Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2 complexed with a3d, so4 |
![]() | Domain d1pzha1: 1pzh A:14-163 [95433] Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2 |
![]() | Domain d1pzhb1: 1pzh B:14-163 [95435] Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2 |
![]() | Domain d1pzhc1: 1pzh C:14-163 [95437] Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2 |
![]() | Domain d1pzhd1: 1pzh D:14-163 [95439] Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2 complexed with nad, oxl |
Timeline for Protein Lactate dehydrogenase from c.2.1.5: LDH N-terminal domain-like: