Lineage for Protein: Malate dehydrogenase

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2449371Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2449372Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2452663Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 2453110Protein Malate dehydrogenase [51849] (13 species)

Species:

  1. 2453111Aquaspirillum arcticum [TaxId:87645] [51856] (3 PDB entries)
    1. Domain for 1b8p:
    2. Domain for 1b8u:
    3. Domain for 1b8v:
  2. 2453115Archaeoglobus fulgidus [TaxId:2234] [110427] (4 PDB entries)
    Uniprot O08349
    1. Domain for 1ojs:
    2. Domain for 1oju:
    3. Domain for 2x0i:
    4. Domain for 2x0j:
  3. 2453120Chlorobium tepidum [TaxId:1097] [69416] (1 PDB entry)
  4. 2453123Chlorobium vibrioforme [TaxId:1098] [69417] (2 PDB entries)
    1. Domains for 1guz:
      1. 2453124Domain d1guza1: 1guz A:1-142 [65586]
        Other proteins in same PDB: d1guza2, d1guzb2, d1guzc2, d1guzd2
        complexed with nad
      2. 2453125Domain d1guzb1: 1guz B:1-142 [65588]
        Other proteins in same PDB: d1guza2, d1guzb2, d1guzc2, d1guzd2
        complexed with nad
      3. 2453126Domain d1guzc1: 1guz C:1-142 [65590]
        Other proteins in same PDB: d1guza2, d1guzb2, d1guzc2, d1guzd2
        complexed with nad
      4. 2453127Domain d1guzd1: 1guz D:1-142 [65592]
        Other proteins in same PDB: d1guza2, d1guzb2, d1guzc2, d1guzd2
        complexed with nad
    2. Domains for 1gv1:
      1. 2453128Domain d1gv1a1: 1gv1 A:1-142 [65598]
        Other proteins in same PDB: d1gv1a2, d1gv1b2, d1gv1c2, d1gv1d2
      2. 2453129Domain d1gv1b1: 1gv1 B:1-142 [65600]
        Other proteins in same PDB: d1gv1a2, d1gv1b2, d1gv1c2, d1gv1d2
      3. 2453130Domain d1gv1c1: 1gv1 C:1-142 [65602]
        Other proteins in same PDB: d1gv1a2, d1gv1b2, d1gv1c2, d1gv1d2
      4. 2453131Domain d1gv1d1: 1gv1 D:1-142 [65604]
        Other proteins in same PDB: d1gv1a2, d1gv1b2, d1gv1c2, d1gv1d2
  5. 2453132Chloroflexus aurantiacus [TaxId:1108] [69415] (7 PDB entries)
    Uniprot P80040
    1. Domains for 1guy:
      1. 2453135Domain d1guya1: 1guy A:1-143 [65582]
        Other proteins in same PDB: d1guya2, d1guyc2
        complexed with cd, nad
      2. 2453136Domain d1guyc1: 1guy C:1-143 [65584]
        Other proteins in same PDB: d1guya2, d1guyc2
        complexed with cd, nad
    2. Domains for 1ur5:
      1. 2453133Domain d1ur5a1: 1ur5 A:2-143 [99807]
        Other proteins in same PDB: d1ur5a2, d1ur5c2
        complexed with cd, cl, na, nad
      2. 2453134Domain d1ur5c1: 1ur5 C:2-143 [99809]
        Other proteins in same PDB: d1ur5a2, d1ur5c2
        complexed with cd, cl, na, nad
    3. Domains for 1uxg:
      1. 2453141Domain d1uxga1: 1uxg A:2-143 [108100]
        Other proteins in same PDB: d1uxga2, d1uxgb2
        complexed with fum, nad; mutant
      2. 2453142Domain d1uxgb1: 1uxg B:2-143 [108102]
        Other proteins in same PDB: d1uxga2, d1uxgb2
        complexed with fum, nad; mutant
    4. Domains for 1uxh:
      1. 2453143Domain d1uxha1: 1uxh A:2-143 [108104]
        Other proteins in same PDB: d1uxha2, d1uxhb2
        complexed with fum, nad; mutant
      2. 2453144Domain d1uxhb1: 1uxh B:2-143 [108106]
        Other proteins in same PDB: d1uxha2, d1uxhb2
        complexed with fum, nad; mutant
    5. Domains for 1uxi:
      1. 2453145Domain d1uxia1: 1uxi A:2-143 [108108]
        Other proteins in same PDB: d1uxia2, d1uxib2
        complexed with fum, na, nad; mutant
      2. 2453146Domain d1uxib1: 1uxi B:2-143 [108110]
        Other proteins in same PDB: d1uxia2, d1uxib2
        complexed with fum, na, nad; mutant
    6. Domains for 1uxj:
      1. 2453137Domain d1uxja1: 1uxj A:2-143 [108112]
        Other proteins in same PDB: d1uxja2, d1uxjc2
        complexed with cd, cl, na, nad; mutant
      2. 2453138Domain d1uxjc1: 1uxj C:2-143 [108114]
        Other proteins in same PDB: d1uxja2, d1uxjc2
        complexed with cd, cl, na, nad; mutant
    7. Domains for 1uxk:
      1. 2453139Domain d1uxka1: 1uxk A:2-143 [108116]
        Other proteins in same PDB: d1uxka2, d1uxkc2
        complexed with cd, cl, na, nad; mutant
      2. 2453140Domain d1uxkc1: 1uxk C:2-143 [108118]
        Other proteins in same PDB: d1uxka2, d1uxkc2
        complexed with cd, cl, na, nad; mutant
  6. 2453147Chloroflexus sp. [TaxId:480224] [236527] (1 PDB entry)
  7. 2453150Escherichia coli [TaxId:562] [51853] (4 PDB entries)
    1. Domain for 1emd:
    2. Domains for 1ib6:
      1. 2453151Domain d1ib6a1: 1ib6 A:1-145 [62146]
        Other proteins in same PDB: d1ib6a2, d1ib6b2, d1ib6c2, d1ib6d2
        complexed with nad, so4
      2. 2453152Domain d1ib6b1: 1ib6 B:1-145 [62148]
        Other proteins in same PDB: d1ib6a2, d1ib6b2, d1ib6c2, d1ib6d2
        complexed with nad, so4
      3. 2453153Domain d1ib6c1: 1ib6 C:1-145 [62150]
        Other proteins in same PDB: d1ib6a2, d1ib6b2, d1ib6c2, d1ib6d2
        complexed with nad, so4
      4. 2453154Domain d1ib6d1: 1ib6 D:1-145 [62152]
        Other proteins in same PDB: d1ib6a2, d1ib6b2, d1ib6c2, d1ib6d2
        complexed with nad, so4
    3. Domains for 1ie3:
      1. 2453157Domain d1ie3a1: 1ie3 A:1-145 [62304]
        Other proteins in same PDB: d1ie3a2, d1ie3b2, d1ie3c2, d1ie3d2
        complexed with nad, pyr
      2. 2453158Domain d1ie3b1: 1ie3 B:1-145 [62306]
        Other proteins in same PDB: d1ie3a2, d1ie3b2, d1ie3c2, d1ie3d2
        complexed with nad, pyr
      3. 2453159Domain d1ie3c1: 1ie3 C:1-145 [62308]
        Other proteins in same PDB: d1ie3a2, d1ie3b2, d1ie3c2, d1ie3d2
        complexed with nad, pyr
      4. 2453160Domain d1ie3d1: 1ie3 D:1-145 [62310]
        Other proteins in same PDB: d1ie3a2, d1ie3b2, d1ie3c2, d1ie3d2
        complexed with nad, pyr
    4. Domain for 2cmd:
  8. 2453161Flaveria bidentis, chloroplast [TaxId:4224] [51852] (1 PDB entry)
  9. 2453163Haloarcula marismortui [TaxId:2238] [51855] (6 PDB entries)
    1. Domains for 1d3a:
      1. 2453174Domain d1d3aa1: 1d3a A:22-162 [30143]
        Other proteins in same PDB: d1d3aa2, d1d3ab2
        complexed with cl, na
      2. 2453175Domain d1d3ab1: 1d3a B:22-162 [30144]
        Other proteins in same PDB: d1d3aa2, d1d3ab2
        complexed with cl, na
    2. Domains for 1gt2:
      1. 2453172Domain d1gt2a3: 1gt2 A:22-162 [302443]
        Other proteins in same PDB: d1gt2a4, d1gt2b4
        automated match to d1o6za1
        complexed with cl, na, nad; mutant
      2. 2453173Domain d1gt2b3: 1gt2 B:22-162 [302445]
        Other proteins in same PDB: d1gt2a4, d1gt2b4
        automated match to d1o6za1
        complexed with cl, na, nad; mutant
    3. Domains for 1hlp:
      1. 2453176Domain d1hlpa1: 1hlp A:21-162 [30145]
        Other proteins in same PDB: d1hlpa2, d1hlpb2
        complexed with nad
      2. 2453177Domain d1hlpb1: 1hlp B:21-162 [30146]
        Other proteins in same PDB: d1hlpa2, d1hlpb2
        complexed with nad
    4. Domains for 1o6z:
      1. 2453164Domain d1o6za1: 1o6z A:22-162 [81107]
        Other proteins in same PDB: d1o6za2, d1o6zb2, d1o6zc2, d1o6zd2
        complexed with cl, nad; mutant
      2. 2453165Domain d1o6zb1: 1o6z B:22-162 [81109]
        Other proteins in same PDB: d1o6za2, d1o6zb2, d1o6zc2, d1o6zd2
        complexed with cl, nad; mutant
      3. 2453166Domain d1o6zc1: 1o6z C:22-162 [81111]
        Other proteins in same PDB: d1o6za2, d1o6zb2, d1o6zc2, d1o6zd2
        complexed with cl, nad; mutant
      4. 2453167Domain d1o6zd1: 1o6z D:22-162 [81113]
        Other proteins in same PDB: d1o6za2, d1o6zb2, d1o6zc2, d1o6zd2
        complexed with cl, nad; mutant
    5. Domains for 2hlp:
      1. 2453168Domain d2hlpa1: 2hlp A:22-162 [30141]
        Other proteins in same PDB: d2hlpa2, d2hlpb2
        complexed with cl, na; mutant
      2. 2453169Domain d2hlpb1: 2hlp B:22-162 [30142]
        Other proteins in same PDB: d2hlpa2, d2hlpb2
        complexed with cl, na; mutant
    6. Domains for 2x0r:
      1. 2453170Domain d2x0ra1: 2x0r A:22-162 [169770]
        Other proteins in same PDB: d2x0ra2, d2x0rb2
        complexed with cl, na, nad; mutant
      2. 2453171Domain d2x0rb1: 2x0r B:22-162 [169772]
        Other proteins in same PDB: d2x0ra2, d2x0rb2
        complexed with cl, na, nad; mutant
  10. 2453178Pig (Sus scrofa) [TaxId:9823] [51850] (3 PDB entries)
    1. Domains for 1mld:
      1. 2453179Domain d1mlda1: 1mld A:1-144 [30122]
        Other proteins in same PDB: d1mlda2, d1mldb2, d1mldc2, d1mldd2
        complexed with cit
      2. 2453180Domain d1mldb1: 1mld B:1-144 [30123]
        Other proteins in same PDB: d1mlda2, d1mldb2, d1mldc2, d1mldd2
        complexed with cit
      3. 2453181Domain d1mldc1: 1mld C:1-144 [30124]
        Other proteins in same PDB: d1mlda2, d1mldb2, d1mldc2, d1mldd2
        complexed with cit
      4. 2453182Domain d1mldd1: 1mld D:1-144 [30125]
        Other proteins in same PDB: d1mlda2, d1mldb2, d1mldc2, d1mldd2
        complexed with cit
    2. Domains for 4mdh:
      1. 2453185Domain d4mdha1: 4mdh A:1-154 [30128]
        Other proteins in same PDB: d4mdha2, d4mdhb2
        complexed with nad, so4
      2. 2453186Domain d4mdhb1: 4mdh B:1-154 [30129]
        Other proteins in same PDB: d4mdha2, d4mdhb2
        complexed with nad, so4
    3. Domains for 5mdh:
      1. 2453183Domain d5mdha1: 5mdh A:1-154 [30126]
        Other proteins in same PDB: d5mdha2, d5mdhb2
        complexed with mak, nad
      2. 2453184Domain d5mdhb1: 5mdh B:1-154 [30127]
        Other proteins in same PDB: d5mdha2, d5mdhb2
        complexed with mak, nad
  11. 2453187Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [51851] (1 PDB entry)
  12. 2453192Thermus flavus [TaxId:274] [51854] (2 PDB entries)
    1. Domains for 1bdm:
      1. 2453193Domain d1bdma1: 1bdm A:0-154 [30137]
        Other proteins in same PDB: d1bdma2, d1bdmb2
        complexed with nax; mutant
      2. 2453194Domain d1bdmb1: 1bdm B:0-154 [30138]
        Other proteins in same PDB: d1bdma2, d1bdmb2
        complexed with nax; mutant
    2. Domains for 1bmd:
      1. 2453195Domain d1bmda1: 1bmd A:0-154 [30139]
        Other proteins in same PDB: d1bmda2, d1bmdb2
        complexed with nad
      2. 2453196Domain d1bmdb1: 1bmd B:0-154 [30140]
        Other proteins in same PDB: d1bmda2, d1bmdb2
        complexed with nad
  13. 2453197Thermus thermophilus [TaxId:274] [82300] (7 PDB entries)
    identical sequence to that from the Thermus flavus enzyme
    1. Domains for 1iz9:
      1. 2453202Domain d1iz9a1: 1iz9 A:1-154 [76984]
        Other proteins in same PDB: d1iz9a2, d1iz9b2
      2. 2453203Domain d1iz9b1: 1iz9 B:1-154 [76986]
        Other proteins in same PDB: d1iz9a2, d1iz9b2
    2. Domains for 1wze:
      1. 2453208Domain d1wzea1: 1wze A:0-153 [121495]
        Other proteins in same PDB: d1wzea2, d1wzeb2
        automated match to d1y7ta1
        complexed with nad
      2. 2453209Domain d1wzeb1: 1wze B:0-153 [121497]
        Other proteins in same PDB: d1wzea2, d1wzeb2
        automated match to d1y7ta1
        complexed with nad
    3. Domains for 1wzi:
      1. 2453206Domain d1wzia1: 1wzi A:0-153 [121503]
        Other proteins in same PDB: d1wzia2, d1wzib2
        automated match to d1y7ta1
        complexed with ndp
      2. 2453207Domain d1wzib1: 1wzi B:0-153 [121505]
        Other proteins in same PDB: d1wzia2, d1wzib2
        automated match to d1y7ta1
        complexed with ndp
    4. Domains for 1y7t:
      1. 2453198Domain d1y7ta1: 1y7t A:0-153 [122718]
        Other proteins in same PDB: d1y7ta2, d1y7tb2
        automated match to d1iz9a1
        complexed with ndp, trs
      2. 2453199Domain d1y7tb1: 1y7t B:0-153 [122720]
        Other proteins in same PDB: d1y7ta2, d1y7tb2
        automated match to d1iz9a1
        complexed with ndp, trs
    5. Domains for 2cvq:
      1. 2453204Domain d2cvqa1: 2cvq A:0-153 [130885]
        Other proteins in same PDB: d2cvqa2, d2cvqb2
        automated match to d1iz9a1
        complexed with ndp, trs
      2. 2453205Domain d2cvqb1: 2cvq B:0-153 [130887]
        Other proteins in same PDB: d2cvqa2, d2cvqb2
        automated match to d1iz9a1
        complexed with ndp, trs
    6. Domains for 4kde:
      1. 2453200Domain d4kdea1: 4kde A:1-154 [236558]
        Other proteins in same PDB: d4kdea2, d4kdea3, d4kdeb2, d4kdeb3
        automated match to d1iz9a1
      2. 2453201Domain d4kdeb1: 4kde B:1-154 [236556]
        Other proteins in same PDB: d4kdea2, d4kdea3, d4kdeb2, d4kdeb3
        automated match to d1iz9a1
    7. Domains for 4kdf:
      1. 2453210Domain d4kdfa1: 4kdf A:1-154 [236559]
        Other proteins in same PDB: d4kdfa2, d4kdfd2
        automated match to d1iz9a1
        complexed with so4
      2. 2453211Domain d4kdfb1: 4kdf B:1-154 [236555]
        Other proteins in same PDB: d4kdfa2, d4kdfd2
        automated match to d1iz9a1
        complexed with so4
      3. 2453212Domain d4kdfc1: 4kdf C:1-154 [236557]
        Other proteins in same PDB: d4kdfa2, d4kdfd2
        automated match to d1iz9a1
        complexed with so4
      4. 2453213Domain d4kdfd1: 4kdf D:1-154 [236554]
        Other proteins in same PDB: d4kdfa2, d4kdfd2
        automated match to d1iz9a1
        complexed with so4

More info for Protein Malate dehydrogenase from c.2.1.5: LDH N-terminal domain-like

Timeline for Protein Malate dehydrogenase from c.2.1.5: LDH N-terminal domain-like: