Lineage for Protein: S-adenosylhomocystein hydrolase

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 238223Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 238224Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families) (S)
  5. 238994Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 proteins)
    this domain interrupts the other domain which defines family
  6. 239047Protein S-adenosylhomocystein hydrolase [51845] (2 species)

Species:

  1. 239048Human (Homo sapiens) [TaxId:9606] [51846] (1 PDB entry)
  2. 239051Rat (Rattus norvegicus) [TaxId:10116] [51847] (6 PDB entries)
    1. Domains for 1b3r:
      1. 239052Domain d1b3ra1: 1b3r A:190-352 [30106]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
      2. 239053Domain d1b3rb1: 1b3r B:190-352 [30107]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
      3. 239054Domain d1b3rc1: 1b3r C:190-352 [30108]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
      4. 239055Domain d1b3rd1: 1b3r D:190-352 [30109]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
        complexed with nad; mutant
    2. Domains for 1d4f:
      1. 239068Domain d1d4fa1: 1d4f A:190-352 [30110]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
      2. 239069Domain d1d4fb1: 1d4f B:190-352 [30111]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
      3. 239070Domain d1d4fc1: 1d4f C:190-352 [30112]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
      4. 239071Domain d1d4fd1: 1d4f D:190-352 [30113]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
        complexed with adn, nad; mutant
    3. Domains for 1d4g:
      1. 239076Domain d1d4ga1: 1d4g A:190-352 [30114]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      2. 239077Domain d1d4gb1: 1d4g B:190-352 [30115]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      3. 239078Domain d1d4gc1: 1d4g C:190-352 [30116]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      4. 239079Domain d1d4gd1: 1d4g D:190-352 [30117]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      5. 239080Domain d1d4ge1: 1d4g E:190-352 [30118]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      6. 239081Domain d1d4gf1: 1d4g F:190-352 [30119]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      7. 239082Domain d1d4gg1: 1d4g G:190-352 [30120]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
      8. 239083Domain d1d4gh1: 1d4g H:190-352 [30121]
        Other proteins in same PDB: d1d4ga2, d1d4gb2, d1d4gc2, d1d4gd2, d1d4ge2, d1d4gf2, d1d4gg2, d1d4gh2
        complexed with dea, nad
    4. Domains for 1k0u:
      1. 239056Domain d1k0ua1: 1k0u A:190-352 [67970]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      2. 239057Domain d1k0ub1: 1k0u B:190-352 [67972]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      3. 239058Domain d1k0uc1: 1k0u C:190-352 [67974]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      4. 239059Domain d1k0ud1: 1k0u D:190-352 [67976]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      5. 239060Domain d1k0ue1: 1k0u E:190-352 [67978]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      6. 239061Domain d1k0uf1: 1k0u F:190-352 [67980]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      7. 239062Domain d1k0ug1: 1k0u G:190-352 [67982]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
      8. 239063Domain d1k0uh1: 1k0u H:190-352 [67984]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
    5. Domains for 1ky4:
      1. 239072Domain d1ky4a1: 1ky4 A:190-352 [77612]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
      2. 239073Domain d1ky4b1: 1ky4 B:1190-1352 [77614]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
      3. 239074Domain d1ky4c1: 1ky4 C:2190-2352 [77616]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
      4. 239075Domain d1ky4d1: 1ky4 D:3190-3352 [77618]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
        complexed with nad
    6. Domains for 1ky5:
      1. 239064Domain d1ky5a1: 1ky5 A:190-352 [77620]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
      2. 239065Domain d1ky5b1: 1ky5 B:1190-1352 [77622]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
      3. 239066Domain d1ky5c1: 1ky5 C:2190-2352 [77624]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
      4. 239067Domain d1ky5d1: 1ky5 D:3190-3352 [77626]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
        complexed with ady, nai; mutant

More info for Protein S-adenosylhomocystein hydrolase from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain

Timeline for Protein S-adenosylhomocystein hydrolase from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain: