Lineage for Protein: S-adenosylhomocystein hydrolase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2092885Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 protein domains)
    this domain interrupts the other domain which defines family
  6. 2092986Protein S-adenosylhomocystein hydrolase [51845] (3 species)

Species:

  1. 2092987Human (Homo sapiens) [TaxId:9606] [51846] (3 PDB entries)
    1. Domains for 1a7a:
      1. 2092989Domain d1a7aa1: 1a7a A:190-352 [30104]
        Other proteins in same PDB: d1a7aa2, d1a7ab2
        complexed with adc, nad
      2. 2092990Domain d1a7ab1: 1a7a B:190-352 [30105]
        Other proteins in same PDB: d1a7aa2, d1a7ab2
        complexed with adc, nad
    2. Domain for 1li4:
    3. Domains for 4yvf:
      1. 2092991Domain d4yvfa2: 4yvf A:190-352 [310110]
        Other proteins in same PDB: d4yvfa1, d4yvfb1
        automated match to d1li4a1
        complexed with nai, xfa
      2. 2092992Domain d4yvfb2: 4yvf B:190-352 [310112]
        Other proteins in same PDB: d4yvfa1, d4yvfb1
        automated match to d1li4a1
        complexed with nai, xfa
  2. 2092993Norway rat (Rattus norvegicus) [TaxId:10116] [51847] (7 PDB entries)
    1. Domains for 1b3r:
      1. 2092994Domain d1b3ra1: 1b3r A:190-352 [30106]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
        complexed with nad
      2. 2092995Domain d1b3rb1: 1b3r B:190-352 [30107]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
        complexed with nad
      3. 2092996Domain d1b3rc1: 1b3r C:190-352 [30108]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
        complexed with nad
      4. 2092997Domain d1b3rd1: 1b3r D:190-352 [30109]
        Other proteins in same PDB: d1b3ra2, d1b3rb2, d1b3rc2, d1b3rd2
        complexed with nad
    2. Domains for 1d4f:
      1. 2093010Domain d1d4fa1: 1d4f A:190-352 [30110]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
        complexed with adn, nad; mutant
      2. 2093011Domain d1d4fb1: 1d4f B:190-352 [30111]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
        complexed with adn, nad; mutant
      3. 2093012Domain d1d4fc1: 1d4f C:190-352 [30112]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
        complexed with adn, nad; mutant
      4. 2093013Domain d1d4fd1: 1d4f D:190-352 [30113]
        Other proteins in same PDB: d1d4fa2, d1d4fb2, d1d4fc2, d1d4fd2
        complexed with adn, nad; mutant
    3. Domains for 1k0u:
      1. 2092998Domain d1k0ua1: 1k0u A:190-352 [67970]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      2. 2092999Domain d1k0ub1: 1k0u B:190-352 [67972]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      3. 2093000Domain d1k0uc1: 1k0u C:190-352 [67974]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      4. 2093001Domain d1k0ud1: 1k0u D:190-352 [67976]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      5. 2093002Domain d1k0ue1: 1k0u E:190-352 [67978]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      6. 2093003Domain d1k0uf1: 1k0u F:190-352 [67980]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      7. 2093004Domain d1k0ug1: 1k0u G:190-352 [67982]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
      8. 2093005Domain d1k0uh1: 1k0u H:190-352 [67984]
        Other proteins in same PDB: d1k0ua2, d1k0ub2, d1k0uc2, d1k0ud2, d1k0ue2, d1k0uf2, d1k0ug2, d1k0uh2
        complexed with dea, nad
    4. Domains for 1ky4:
      1. 2093014Domain d1ky4a1: 1ky4 A:190-352 [77612]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
        complexed with nad
      2. 2093015Domain d1ky4b1: 1ky4 B:1190-1352 [77614]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
        complexed with nad
      3. 2093016Domain d1ky4c1: 1ky4 C:2190-2352 [77616]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
        complexed with nad
      4. 2093017Domain d1ky4d1: 1ky4 D:3190-3352 [77618]
        Other proteins in same PDB: d1ky4a2, d1ky4b2, d1ky4c2, d1ky4d2
        complexed with nad
    5. Domains for 1ky5:
      1. 2093006Domain d1ky5a1: 1ky5 A:190-352 [77620]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
        complexed with ady, nai; mutant
      2. 2093007Domain d1ky5b1: 1ky5 B:1190-1352 [77622]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
        complexed with ady, nai; mutant
      3. 2093008Domain d1ky5c1: 1ky5 C:2190-2352 [77624]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
        complexed with ady, nai; mutant
      4. 2093009Domain d1ky5d1: 1ky5 D:3190-3352 [77626]
        Other proteins in same PDB: d1ky5a2, d1ky5b2, d1ky5c2, d1ky5d2
        complexed with ady, nai; mutant
    6. Domains for 1xwf:
      1. 2093018Domain d1xwfa1: 1xwf A:190-352 [122392]
        Other proteins in same PDB: d1xwfa2, d1xwfb2, d1xwfc2, d1xwfd2
        automatically matched to d1d4fa1
        complexed with adn, nad
      2. 2093019Domain d1xwfb1: 1xwf B:190-352 [122394]
        Other proteins in same PDB: d1xwfa2, d1xwfb2, d1xwfc2, d1xwfd2
        automatically matched to d1d4fa1
        complexed with adn, nad
      3. 2093020Domain d1xwfc1: 1xwf C:190-352 [122396]
        Other proteins in same PDB: d1xwfa2, d1xwfb2, d1xwfc2, d1xwfd2
        automatically matched to d1d4fa1
        complexed with adn, nad
      4. 2093021Domain d1xwfd1: 1xwf D:190-352 [122398]
        Other proteins in same PDB: d1xwfa2, d1xwfb2, d1xwfc2, d1xwfd2
        automatically matched to d1d4fa1
        complexed with adn, nad
    7. Domains for 2h5l:
      1. 2093022Domain d2h5la1: 2h5l A:190-352 [136151]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      2. 2093023Domain d2h5lb1: 2h5l B:190-352 [136153]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      3. 2093024Domain d2h5lc1: 2h5l C:190-352 [136155]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      4. 2093025Domain d2h5ld1: 2h5l D:190-352 [136157]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      5. 2093026Domain d2h5le1: 2h5l E:190-352 [136159]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      6. 2093027Domain d2h5lf1: 2h5l F:190-352 [136161]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      7. 2093028Domain d2h5lg1: 2h5l G:190-352 [136163]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
      8. 2093029Domain d2h5lh1: 2h5l H:190-352 [136165]
        Other proteins in same PDB: d2h5la2, d2h5lb2, d2h5lc2, d2h5ld2, d2h5le2, d2h5lf2, d2h5lg2, d2h5lh2
        automated match to d1k0ua1
        complexed with 3dd, nad
  3. 2093030Plasmodium falciparum, isolate 3D7 [TaxId:5833] [117431] (1 PDB entry)
    Uniprot P50250

More info for Protein S-adenosylhomocystein hydrolase from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain

Timeline for Protein S-adenosylhomocystein hydrolase from c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain: