Lineage for Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 238223Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 238224Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families) (S)
  5. 238994Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 proteins)
    this domain interrupts the other domain which defines family

Proteins:

  1. 238995D-2-hydroxyisocaproate dehydrogenase [51835] (1 species)
  2. 238998D-glycerate dehydrogenase [51837] (1 species)
  3. 239002D-lactate dehydrogenase [51841] (1 species)
  4. 239012Formate dehydrogenase [51831] (1 species)
  5. 239018L-alanine dehydrogenase [51843] (1 species)
  6. 239023Nicotinamide nucleotide transhydrogenase dI component [63937] (1 species)
    L-alanine dehydrogenase homologue
  7. 239039Phosphoglycerate dehydrogenase [51839] (1 species)
    has additional C-terminal domain of the ferredoxin fold
  8. 239043Putative formate dehydrogenase [51833] (1 species)
  9. 239047S-adenosylhomocystein hydrolase [51845] (2 species)
    1. 239048Species Human (Homo sapiens) [TaxId:9606] [51846] (1 PDB entry)
    2. 239051Species Rat (Rattus norvegicus) [TaxId:10116] [51847] (6 PDB entries)
  10. 239084Transcription corepressor CtbP [82298] (1 species)
    C-terminal binding protein 1; a dehydrogenase

More info for Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain

Timeline for Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain: