Lineage for Protein: Aspartate beta-semialdehyde dehydrogenase

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2102557Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2102558Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2104791Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 protein domains)
    family members also share a common alpha+beta fold in C-terminal domain
  6. 2104834Protein Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

Species:

  1. 2104835Escherichia coli [TaxId:562] [51814] (4 PDB entries)
    Uniprot P00353
    1. Domains for 1brm:
      1. 2104843Domain d1brma1: 1brm A:1-133,A:355-367 [30030]
        Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
      2. 2104844Domain d1brmb1: 1brm B:1-133,B:355-367 [30031]
        Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
      3. 2104845Domain d1brmc1: 1brm C:1-133,C:355-367 [30032]
        Other proteins in same PDB: d1brma2, d1brmb2, d1brmc2
    2. Domains for 1gl3:
      1. 2104841Domain d1gl3a1: 1gl3 A:1-133,A:355-367 [65282]
        Other proteins in same PDB: d1gl3a2, d1gl3b2
        complexed with cys, ndp
      2. 2104842Domain d1gl3b1: 1gl3 B:1-133,B:355-367 [65284]
        Other proteins in same PDB: d1gl3a2, d1gl3b2
        complexed with cys, ndp
    3. Domains for 1t4b:
      1. 2104836Domain d1t4ba1: 1t4b A:1-133,A:355-367 [106406]
        Other proteins in same PDB: d1t4ba2, d1t4bb2
        complexed with na
      2. 2104837Domain d1t4bb1: 1t4b B:1-133,B:355-367 [106408]
        Other proteins in same PDB: d1t4ba2, d1t4bb2
        complexed with na
    4. Domains for 1t4d:
      1. 2104838Domain d1t4da1: 1t4d A:1-133,A:355-367 [106412]
        Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
      2. 2104839Domain d1t4db1: 1t4d B:1-133,B:355-367 [106414]
        Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
      3. 2104840Domain d1t4dc1: 1t4d C:1-133,C:355-367 [106416]
        Other proteins in same PDB: d1t4da2, d1t4db2, d1t4dc2
  2. 2104846Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)
    Uniprot P44801
    1. Domains for 1nwc:
      1. 2104853Domain d1nwca1: 1nwc A:1-133,A:358-371 [92229]
        Other proteins in same PDB: d1nwca2, d1nwcb2
      2. 2104854Domain d1nwcb1: 1nwc B:1-133,B:358-371 [92231]
        Other proteins in same PDB: d1nwca2, d1nwcb2
    2. Domains for 1nwh:
      1. 2104851Domain d1nwha1: 1nwh A:1-133,A:358-371 [92233]
        Other proteins in same PDB: d1nwha2, d1nwhb2
      2. 2104852Domain d1nwhb1: 1nwh B:1-133,B:358-371 [92235]
        Other proteins in same PDB: d1nwha2, d1nwhb2
    3. Domain for 1nx6:
    4. Domain for 1oza:
    5. Domain for 1pqp:
    6. Domains for 1pqu:
      1. 2104847Domain d1pqua1: 1pqu A:1-133,A:358-371 [104288]
        Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
        complexed with cac, cys, nap; mutant
      2. 2104848Domain d1pqub1: 1pqu B:1-133,B:358-371 [104290]
        Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
        complexed with cac, cys, nap; mutant
      3. 2104849Domain d1pquc1: 1pqu C:1-133,C:358-371 [104292]
        Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
        complexed with cac, cys, nap; mutant
      4. 2104850Domain d1pqud1: 1pqu D:1-133,D:358-371 [104294]
        Other proteins in same PDB: d1pqua2, d1pqub2, d1pquc2, d1pqud2
        complexed with cac, cys, nap; mutant
    7. Domain for 1pr3:
    8. Domain for 1ps8:
    9. Domain for 1pu2:
    10. Domains for 1q2x:
      1. 2104860Domain d1q2xa1: 1q2x A:1-133,A:358-371 [104503]
        Other proteins in same PDB: d1q2xa2, d1q2xb2
        mutant
      2. 2104861Domain d1q2xb1: 1q2x B:1-133,B:358-371 [104505]
        Other proteins in same PDB: d1q2xa2, d1q2xb2
        mutant
    11. Domain for 1ta4:
    12. Domain for 1tb4:
  3. 2104865Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (18 PDB entries)
    Uniprot Q8DQ00 2-127,330-357
    1. Domains for 2gyy:
      1. 2104884Domain d2gyya1: 2gyy A:2-127,A:330-357 [135879]
        Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
      2. 2104885Domain d2gyyb1: 2gyy B:2-127,B:330-356 [135881]
        Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
        automated match to d2gyya1
      3. 2104886Domain d2gyyc1: 2gyy C:2-127,C:330-358 [135883]
        Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
        automated match to d2gyya1
      4. 2104887Domain d2gyyd1: 2gyy D:3-127,D:330-350 [135885]
        Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
        automated match to d2gyya1
    2. Domains for 2gz1:
      1. 2104872Domain d2gz1a1: 2gz1 A:2-127,A:330-358 [135887]
        Other proteins in same PDB: d2gz1a2, d2gz1b2
        automated match to d2gyya1
        complexed with nap
      2. 2104873Domain d2gz1b1: 2gz1 B:2-127,B:330-358 [135889]
        Other proteins in same PDB: d2gz1a2, d2gz1b2
        automated match to d2gyya1
        complexed with nap
    3. Domains for 2gz2:
      1. 2104894Domain d2gz2a1: 2gz2 A:2-127,A:330-358 [135891]
        Other proteins in same PDB: d2gz2a2, d2gz2b2
        automated match to d2gyya1
        complexed with a2p
      2. 2104895Domain d2gz2b1: 2gz2 B:2-127,B:330-358 [135893]
        Other proteins in same PDB: d2gz2a2, d2gz2b2
        automated match to d2gyya1
        complexed with a2p
    4. Domains for 2gz3:
      1. 2104898Domain d2gz3a1: 2gz3 A:2-127,A:330-358 [135895]
        Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
        automated match to d2gyya1
        complexed with as2, nap
      2. 2104899Domain d2gz3b1: 2gz3 B:2-127,B:330-348 [197992]
        Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
        automated match to d2gyya1
        complexed with as2, nap
      3. 2104900Domain d2gz3c1: 2gz3 C:2-127,C:330-358 [135897]
        Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
        automated match to d2gyya1
        complexed with as2, nap
      4. 2104901Domain d2gz3d1: 2gz3 D:2-127,D:330-358 [135899]
        Other proteins in same PDB: d2gz3a2, d2gz3b2, d2gz3c2, d2gz3d2
        automated match to d2gyya1
        complexed with as2, nap
    5. Domains for 3pwk:
      1. 2104866Domain d3pwka1: 3pwk A:2-127,A:330-358 [214954]
        Other proteins in same PDB: d3pwka2, d3pwkb2, d3pwkb3
        automated match to d2gyya1
        complexed with 25a, edo, l14, na
      2. 2104867Domain d3pwkb1: 3pwk B:2-127,B:330-358 [214956]
        Other proteins in same PDB: d3pwka2, d3pwkb2, d3pwkb3
        automated match to d2gyya1
        complexed with 25a, edo, l14, na
    6. Domains for 3pws:
      1. 2104880Domain d3pwsa1: 3pws A:2-127,A:330-358 [214958]
        Other proteins in same PDB: d3pwsa2, d3pwsb2
        automated match to d2gyya1
        complexed with 11c, a2p, na
      2. 2104881Domain d3pwsb1: 3pws B:2-127,B:330-358 [214960]
        Other proteins in same PDB: d3pwsa2, d3pwsb2
        automated match to d2gyya1
        complexed with 11c, a2p, na
    7. Domains for 3pyl:
      1. 2104906Domain d3pyla1: 3pyl A:2-127,A:330-358 [214972]
        Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
        automated match to d2gyya1
        complexed with 2ra
      2. 2104907Domain d3pylb1: 3pyl B:2-127,B:330-355 [214974]
        Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
        automated match to d2gyya1
        complexed with 2ra
      3. 2104908Domain d3pylc1: 3pyl C:2-127,C:330-358 [214976]
        Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
        automated match to d2gyya1
        complexed with 2ra
      4. 2104909Domain d3pyld1: 3pyl D:2-127,D:330-357 [214978]
        Other proteins in same PDB: d3pyla2, d3pyla3, d3pylb2, d3pylc2, d3pylc3, d3pyld2
        automated match to d2gyya1
        complexed with 2ra
    8. Domains for 3pyx:
      1. 2104874Domain d3pyxa1: 3pyx A:2-127,A:330-358 [214980]
        Other proteins in same PDB: d3pyxa2, d3pyxb2, d3pyxb3
        automated match to d2gyya1
        complexed with 12t, edo, na, nap
      2. 2104875Domain d3pyxb1: 3pyx B:2-127,B:330-358 [214982]
        Other proteins in same PDB: d3pyxa2, d3pyxb2, d3pyxb3
        automated match to d2gyya1
        complexed with 12t, edo, na, nap
    9. Domains for 3pzb:
      1. 2104896Domain d3pzba1: 3pzb A:2-127,A:330-358 [214984]
        Other proteins in same PDB: d3pzba2, d3pzbb2, d3pzbb3
        automated match to d2gyya1
        complexed with 2ra, edo, na, nap
      2. 2104897Domain d3pzbb1: 3pzb B:2-127,B:330-358 [214986]
        Other proteins in same PDB: d3pzba2, d3pzbb2, d3pzbb3
        automated match to d2gyya1
        complexed with 2ra, edo, na, nap
    10. Domains for 3q11:
      1. 2104878Domain d3q11a1: 3q11 A:2-127,A:330-358 [215017]
        Other proteins in same PDB: d3q11a2, d3q11a3, d3q11b2
        automated match to d2gyya1
        complexed with edo, na, nap, p4f
      2. 2104879Domain d3q11b1: 3q11 B:2-127,B:330-358 [215019]
        Other proteins in same PDB: d3q11a2, d3q11a3, d3q11b2
        automated match to d2gyya1
        complexed with edo, na, nap, p4f
    11. Domains for 3q1l:
      1. 2104902Domain d3q1la1: 3q1l A:2-127,A:330-358 [215029]
        Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
        automated match to d2gyya1
        complexed with dhl
      2. 2104903Domain d3q1lb1: 3q1l B:2-127,B:330-357 [215031]
        Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
        automated match to d2gyya1
        complexed with dhl
      3. 2104904Domain d3q1lc1: 3q1l C:2-127,C:330-358 [215033]
        Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
        automated match to d2gyya1
        complexed with dhl
      4. 2104905Domain d3q1ld1: 3q1l D:2-127,D:330-357 [215035]
        Other proteins in same PDB: d3q1la2, d3q1lb2, d3q1lc2, d3q1lc3, d3q1ld2
        automated match to d2gyya1
        complexed with dhl
    12. Domains for 4r3n:
      1. 2104868Domain d4r3na1: 4r3n A:2-127,A:330-358 [261735]
        Other proteins in same PDB: d4r3na2, d4r3nb2
        automated match to d2gyya1
        complexed with 3gq, act, edo, na, nap
      2. 2104869Domain d4r3nb1: 4r3n B:2-127,B:330-348 [261670]
        Other proteins in same PDB: d4r3na2, d4r3nb2
        automated match to d2gyya1
        complexed with 3gq, act, edo, na, nap
    13. Domains for 4r3w:
      1. 2104892Domain d4r3wa1: 4r3w A:2-127,A:330-358 [261557]
        Other proteins in same PDB: d4r3wa2, d4r3wb2
        automated match to d2gyya1
        complexed with 3gq, a2p, act, edo, na
      2. 2104893Domain d4r3wb1: 4r3w B:2-127,B:330-348 [261667]
        Other proteins in same PDB: d4r3wa2, d4r3wb2
        automated match to d2gyya1
        complexed with 3gq, a2p, act, edo, na
    14. Domains for 4r41:
      1. 2104876Domain d4r41a1: 4r41 A:2-127,A:330-358 [261560]
        Other proteins in same PDB: d4r41a2, d4r41b2
        automated match to d2gyya1
        complexed with 4no, act, edo, na, nap
      2. 2104877Domain d4r41b1: 4r41 B:2-127,B:330-348 [261734]
        Other proteins in same PDB: d4r41a2, d4r41b2
        automated match to d2gyya1
        complexed with 4no, act, edo, na, nap
    15. Domains for 4r4j:
      1. 2104870Domain d4r4ja1: 4r4j A:2-127,A:330-358 [261669]
        Other proteins in same PDB: d4r4ja2, d4r4ja3, d4r4jb2
        automated match to d2gyya1
        complexed with 3jl, edo, na, nap
      2. 2104871Domain d4r4jb1: 4r4j B:2-127,B:330-358 [261562]
        Other proteins in same PDB: d4r4ja2, d4r4ja3, d4r4jb2
        automated match to d2gyya1
        complexed with 3jl, edo, na, nap
    16. Domains for 4r51:
      1. 2104882Domain d4r51a1: 4r51 A:2-127,A:330-358 [261566]
        Other proteins in same PDB: d4r51a2, d4r51a3, d4r51b2
        automated match to d2gyya1
        complexed with act, edo, na, nap, pht
      2. 2104883Domain d4r51b1: 4r51 B:2-127,B:330-348 [261739]
        Other proteins in same PDB: d4r51a2, d4r51a3, d4r51b2
        automated match to d2gyya1
        complexed with act, edo, na, nap, pht
    17. Domains for 4r54:
      1. 2104890Domain d4r54a1: 4r54 A:2-127,A:330-358 [261678]
        Other proteins in same PDB: d4r54a2, d4r54b2
        automated match to d2gyya1
        complexed with 3jm, act, na, nap
      2. 2104891Domain d4r54b1: 4r54 B:2-127,B:330-358 [261675]
        Other proteins in same PDB: d4r54a2, d4r54b2
        automated match to d2gyya1
        complexed with 3jm, act, na, nap
    18. Domains for 4r5h:
      1. 2104888Domain d4r5ha1: 4r5h A:2-127,A:330-358 [261674]
        Other proteins in same PDB: d4r5ha2, d4r5ha3, d4r5hb2
        automated match to d2gyya1
        complexed with 3jn, edo, na, nap
      2. 2104889Domain d4r5hb1: 4r5h B:2-127,B:330-358 [261741]
        Other proteins in same PDB: d4r5ha2, d4r5ha3, d4r5hb2
        automated match to d2gyya1
        complexed with 3jn, edo, na, nap
  4. 2104910Vibrio cholerae [TaxId:666] [82297] (4 PDB entries)
    1. Domains for 1mb4:
      1. 2104913Domain d1mb4a1: 1mb4 A:1-132,A:355-369 [78908]
        Other proteins in same PDB: d1mb4a2, d1mb4b2
        complexed with cys, ndp
      2. 2104914Domain d1mb4b1: 1mb4 B:1-132,B:355-369 [78910]
        Other proteins in same PDB: d1mb4a2, d1mb4b2
        complexed with cys, ndp
    2. Domain for 1mc4:
    3. Domains for 3pzr:
      1. 2104911Domain d3pzra1: 3pzr A:1-132,A:355-370 [214992]
        Other proteins in same PDB: d3pzra2, d3pzrb2
        automated match to d1mb4a1
        complexed with cys, na, nap
      2. 2104912Domain d3pzrb1: 3pzr B:1-132,B:355-370 [214994]
        Other proteins in same PDB: d3pzra2, d3pzrb2
        automated match to d1mb4a1
        complexed with cys, na, nap
    4. Domains for 3q0e:
      1. 2104915Domain d3q0ea1: 3q0e A:1-132,A:355-369 [215007]
        Other proteins in same PDB: d3q0ea2, d3q0eb2
        automated match to d1mb4a1
        complexed with act, cys, edo, so4
      2. 2104916Domain d3q0eb1: 3q0e B:1-132,B:355-369 [215009]
        Other proteins in same PDB: d3q0ea2, d3q0eb2
        automated match to d1mb4a1
        complexed with act, cys, edo, so4

More info for Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Protein Aspartate beta-semialdehyde dehydrogenase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain: