Class c: Alpha and beta proteins (a/b) [51349] (117 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families) |
Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (12 proteins) family members also share a common alpha+beta fold in C-terminal domain |
Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801] (13 species) |
Archaeon Methanothermus fervidus [TaxId:2180] [51807] (1 PDB entry) |
Domain d1cf2o1: 1cf2 O:1-138,O:304-336 [29994] Other proteins in same PDB: d1cf2o2, d1cf2p2, d1cf2q2, d1cf2r2 |
Domain d1cf2p1: 1cf2 P:1-138,P:304-336 [29996] Other proteins in same PDB: d1cf2o2, d1cf2p2, d1cf2q2, d1cf2r2 |
Domain d1cf2q1: 1cf2 Q:1-138,Q:304-336 [29995] Other proteins in same PDB: d1cf2o2, d1cf2p2, d1cf2q2, d1cf2r2 |
Domain d1cf2r1: 1cf2 R:1-138,R:304-336 [29997] Other proteins in same PDB: d1cf2o2, d1cf2p2, d1cf2q2, d1cf2r2 complexed with nap, so4 |
Archaeon Sulfolobus solfataricus [TaxId:2287] [51806] (1 PDB entry) |
Domain d1b7go1: 1b7g O:1-138,O:301-340 [29992] Other proteins in same PDB: d1b7go2, d1b7gq2 |
Domain d1b7gq1: 1b7g Q:1-138,Q:301-340 [29993] Other proteins in same PDB: d1b7go2, d1b7gq2 CASP3 complexed with so4; mutant |
Bacillus stearothermophilus, nca 1503 [TaxId:1422] [51803] (6 PDB entries) |
Domain d1dbvo1: 1dbv O:0-148,O:313-333 [29966] Other proteins in same PDB: d1dbvo2, d1dbvp2, d1dbvq2, d1dbvr2 |
Domain d1dbvp1: 1dbv P:0-148,P:313-333 [29967] Other proteins in same PDB: d1dbvo2, d1dbvp2, d1dbvq2, d1dbvr2 |
Domain d1dbvq1: 1dbv Q:0-148,Q:313-333 [29968] Other proteins in same PDB: d1dbvo2, d1dbvp2, d1dbvq2, d1dbvr2 |
Domain d1dbvr1: 1dbv R:0-148,R:313-333 [29969] Other proteins in same PDB: d1dbvo2, d1dbvp2, d1dbvq2, d1dbvr2 complexed with nad, so4; mutant |
Domain d1gd1o1: 1gd1 O:0-148,O:313-333 [29962] Other proteins in same PDB: d1gd1o2, d1gd1p2, d1gd1q2, d1gd1r2 |
Domain d1gd1p1: 1gd1 P:0-148,P:313-333 [29963] Other proteins in same PDB: d1gd1o2, d1gd1p2, d1gd1q2, d1gd1r2 |
Domain d1gd1q1: 1gd1 Q:0-148,Q:313-333 [29964] Other proteins in same PDB: d1gd1o2, d1gd1p2, d1gd1q2, d1gd1r2 |
Domain d1gd1r1: 1gd1 R:0-148,R:313-333 [29965] Other proteins in same PDB: d1gd1o2, d1gd1p2, d1gd1q2, d1gd1r2 complexed with nad, so4 |
Domain d2dbvo1: 2dbv O:0-148,O:313-333 [29970] Other proteins in same PDB: d2dbvo2, d2dbvp2, d2dbvq2, d2dbvr2 |
Domain d2dbvp1: 2dbv P:0-148,P:313-333 [29971] Other proteins in same PDB: d2dbvo2, d2dbvp2, d2dbvq2, d2dbvr2 |
Domain d2dbvq1: 2dbv Q:0-148,Q:313-333 [29972] Other proteins in same PDB: d2dbvo2, d2dbvp2, d2dbvq2, d2dbvr2 |
Domain d2dbvr1: 2dbv R:0-148,R:313-333 [29973] Other proteins in same PDB: d2dbvo2, d2dbvp2, d2dbvq2, d2dbvr2 complexed with ndp, so4; mutant |
Domain d2gd1o1: 2gd1 O:0-148,O:313-333 [29978] Other proteins in same PDB: d2gd1o2, d2gd1p2, d2gd1q2, d2gd1r2 |
Domain d2gd1p1: 2gd1 P:0-148,P:313-333 [29979] Other proteins in same PDB: d2gd1o2, d2gd1p2, d2gd1q2, d2gd1r2 |
Domain d2gd1q1: 2gd1 Q:0-148,Q:313-333 [29980] Other proteins in same PDB: d2gd1o2, d2gd1p2, d2gd1q2, d2gd1r2 |
Domain d2gd1r1: 2gd1 R:0-148,R:313-333 [29981] Other proteins in same PDB: d2gd1o2, d2gd1p2, d2gd1q2, d2gd1r2 complexed with so4 |
Domain d3dbvo1: 3dbv O:0-148,O:313-333 [29982] Other proteins in same PDB: d3dbvo2, d3dbvp2, d3dbvq2, d3dbvr2 |
Domain d3dbvp1: 3dbv P:0-148,P:313-333 [29983] Other proteins in same PDB: d3dbvo2, d3dbvp2, d3dbvq2, d3dbvr2 |
Domain d3dbvq1: 3dbv Q:0-148,Q:313-333 [29984] Other proteins in same PDB: d3dbvo2, d3dbvp2, d3dbvq2, d3dbvr2 |
Domain d3dbvr1: 3dbv R:0-148,R:313-333 [29985] Other proteins in same PDB: d3dbvo2, d3dbvp2, d3dbvq2, d3dbvr2 complexed with nad, so4; mutant |
Domain d4dbvo1: 4dbv O:0-148,O:313-333 [29974] Other proteins in same PDB: d4dbvo2, d4dbvp2, d4dbvq2, d4dbvr2 |
Domain d4dbvp1: 4dbv P:0-148,P:313-333 [29975] Other proteins in same PDB: d4dbvo2, d4dbvp2, d4dbvq2, d4dbvr2 |
Domain d4dbvq1: 4dbv Q:0-148,Q:313-333 [29976] Other proteins in same PDB: d4dbvo2, d4dbvp2, d4dbvq2, d4dbvr2 |
Domain d4dbvr1: 4dbv R:0-148,R:313-333 [29977] Other proteins in same PDB: d4dbvo2, d4dbvp2, d4dbvq2, d4dbvr2 complexed with ndp, so4; mutant |
Escherichia coli [TaxId:562] [51802] (6 PDB entries) |
Domain d1dc3a1: 1dc3 A:0-148,A:313-330 [29958] Other proteins in same PDB: d1dc3a2, d1dc3b2 |
Domain d1dc3b1: 1dc3 B:0-148,B:313-330 [29959] Other proteins in same PDB: d1dc3a2, d1dc3b2 |
Domain d1dc4a1: 1dc4 A:0-148,A:313-330 [29960] Other proteins in same PDB: d1dc4a2, d1dc4b2 |
Domain d1dc4b1: 1dc4 B:0-148,B:313-330 [29961] Other proteins in same PDB: d1dc4a2, d1dc4b2 complexed with g3h |
Domain d1dc5a1: 1dc5 A:0-148,A:313-330 [29952] Other proteins in same PDB: d1dc5a2, d1dc5b2 |
Domain d1dc5b1: 1dc5 B:0-148,B:313-330 [29953] Other proteins in same PDB: d1dc5a2, d1dc5b2 |
Domain d1dc6a1: 1dc6 A:0-148,A:313-330 [29956] Other proteins in same PDB: d1dc6a2, d1dc6b2 |
Domain d1dc6b1: 1dc6 B:0-148,B:313-330 [29957] Other proteins in same PDB: d1dc6a2, d1dc6b2 complexed with nad |
Domain d1gado1: 1gad O:0-148,O:313-330 [29950] Other proteins in same PDB: d1gado2, d1gadp2 |
Domain d1gadp1: 1gad P:0-148,P:313-330 [29951] Other proteins in same PDB: d1gado2, d1gadp2 complexed with nad |
Domain d1gaeo1: 1gae O:0-148,O:313-330 [29954] Other proteins in same PDB: d1gaeo2, d1gaep2 |
Domain d1gaep1: 1gae P:0-148,P:313-330 [29955] Other proteins in same PDB: d1gaeo2, d1gaep2 complexed with nad; mutant |
Human (Homo sapiens) [TaxId:9606] [51812] (1 PDB entry) |
Domain d3gpdg1: 3gpd G:1-150,G:315-334 [30029] Other proteins in same PDB: d3gpdg2, d3gpdr2 complexed with ips, nad, sps |
Domain d3gpdr1: 3gpd R:1-150,R:315-334 [30028] Other proteins in same PDB: d3gpdg2, d3gpdr2 |
Leishmania mexicana [TaxId:5665] [51809] (5 PDB entries) |
Domain d1a7ka1: 1a7k A:1-165,A:335-358 [30008] Other proteins in same PDB: d1a7ka2, d1a7kb2, d1a7kc2, d1a7kd2 |
Domain d1a7kb1: 1a7k B:1-165,B:335-358 [30009] Other proteins in same PDB: d1a7ka2, d1a7kb2, d1a7kc2, d1a7kd2 |
Domain d1a7kc1: 1a7k C:1-165,C:335-358 [30010] Other proteins in same PDB: d1a7ka2, d1a7kb2, d1a7kc2, d1a7kd2 |
Domain d1a7kd1: 1a7k D:1-165,D:335-358 [30011] Other proteins in same PDB: d1a7ka2, d1a7kb2, d1a7kc2, d1a7kd2 complexed with nad, po4 |
Domain d1gypa1: 1gyp A:1-165,A:335-358 [30004] Other proteins in same PDB: d1gypa2, d1gypb2, d1gypc2, d1gypd2 |
Domain d1gypb1: 1gyp B:1-165,B:335-358 [30005] Other proteins in same PDB: d1gypa2, d1gypb2, d1gypc2, d1gypd2 |
Domain d1gypc1: 1gyp C:1-165,C:335-358 [30006] Other proteins in same PDB: d1gypa2, d1gypb2, d1gypc2, d1gypd2 |
Domain d1gypd1: 1gyp D:1-165,D:335-358 [30007] Other proteins in same PDB: d1gypa2, d1gypb2, d1gypc2, d1gypd2 complexed with nad, po4 |
Domain d1gyqa1: 1gyq A:1-165,A:335-358 [30012] Other proteins in same PDB: d1gyqa2, d1gyqb2, d1gyqc2, d1gyqd2 |
Domain d1gyqb1: 1gyq B:1-165,B:335-358 [30013] Other proteins in same PDB: d1gyqa2, d1gyqb2, d1gyqc2, d1gyqd2 |
Domain d1gyqc1: 1gyq C:1-165,C:335-358 [30014] Other proteins in same PDB: d1gyqa2, d1gyqb2, d1gyqc2, d1gyqd2 |
Domain d1gyqd1: 1gyq D:1-165,D:335-358 [30015] Other proteins in same PDB: d1gyqa2, d1gyqb2, d1gyqc2, d1gyqd2 complexed with nbd |
Domain d1i32a1: 1i32 A:1-165,A:335-358 [65993] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 |
Domain d1i32b1: 1i32 B:1-165,B:335-358 [65995] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 |
Domain d1i32c1: 1i32 C:1-165,C:335-358 [65997] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 |
Domain d1i32d1: 1i32 D:1-165,D:335-358 [65999] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 |
Domain d1i32e1: 1i32 E:1-165,E:335-358 [66001] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 |
Domain d1i32f1: 1i32 F:1-165,F:335-358 [66003] Other proteins in same PDB: d1i32a2, d1i32b2, d1i32c2, d1i32d2, d1i32e2, d1i32f2 complexed with nmd |
Domain d1i33a1: 1i33 A:1-165,A:335-358 [66005] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 |
Domain d1i33b1: 1i33 B:1-165,B:335-358 [66007] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 |
Domain d1i33c1: 1i33 C:1-165,C:335-358 [66009] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 |
Domain d1i33d1: 1i33 D:1-165,D:335-358 [66011] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 |
Domain d1i33e1: 1i33 E:1-165,E:335-358 [66013] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 |
Domain d1i33f1: 1i33 F:1-165,F:335-358 [66015] Other proteins in same PDB: d1i33a2, d1i33b2, d1i33c2, d1i33d2, d1i33e2, d1i33f2 complexed with tnd |
Lobster (Homarus americanus) [51810] (2 PDB entries) |
Domain d1gpdg1: 1gpd G:1-148,G:313-334 [30020] Other proteins in same PDB: d1gpdg2, d1gpdr2 |
Domain d1gpdr1: 1gpd R:1-148,R:313-334 [30021] Other proteins in same PDB: d1gpdg2, d1gpdr2 complexed with ips, nad, sps |
Domain d4gpd11: 4gpd 1:1-147,1:312-333 [30016] Other proteins in same PDB: d4gpd12, d4gpd22, d4gpd32, d4gpd42 |
Domain d4gpd21: 4gpd 2:1-147,2:312-333 [30017] Other proteins in same PDB: d4gpd12, d4gpd22, d4gpd32, d4gpd42 |
Domain d4gpd31: 4gpd 3:1-147,3:312-333 [30018] Other proteins in same PDB: d4gpd12, d4gpd22, d4gpd32, d4gpd42 |
Domain d4gpd41: 4gpd 4:1-147,4:312-333 [30019] Other proteins in same PDB: d4gpd12, d4gpd22, d4gpd32, d4gpd42 |
Lobster (Palinurus versicolor) [51811] (5 PDB entries) |
Domain d1crwg1: 1crw G:1-148,G:313-334 [30026] Other proteins in same PDB: d1crwg2, d1crwr2 |
Domain d1crwr1: 1crw R:1-148,R:313-334 [30027] Other proteins in same PDB: d1crwg2, d1crwr2 |
Domain d1dssg1: 1dss G:1-148,G:313-334 [30022] Other proteins in same PDB: d1dssg2, d1dssr2 |
Domain d1dssr1: 1dss R:1-148,R:313-334 [30023] Other proteins in same PDB: d1dssg2, d1dssr2 complexed with nad, so4 |
Domain d1ihxa1: 1ihx A:1-148,A:313-334 [71211] Other proteins in same PDB: d1ihxa2, d1ihxb2, d1ihxc2, d1ihxd2 |
Domain d1ihxb1: 1ihx B:1-148,B:313-334 [71213] Other proteins in same PDB: d1ihxa2, d1ihxb2, d1ihxc2, d1ihxd2 |
Domain d1ihxc1: 1ihx C:1-148,C:313-334 [71215] Other proteins in same PDB: d1ihxa2, d1ihxb2, d1ihxc2, d1ihxd2 |
Domain d1ihxd1: 1ihx D:1-148,D:313-334 [71217] Other proteins in same PDB: d1ihxa2, d1ihxb2, d1ihxc2, d1ihxd2 complexed with snd, so4 |
Domain d1ihya1: 1ihy A:1-148,A:313-334 [71219] Other proteins in same PDB: d1ihya2, d1ihyb2, d1ihyc2, d1ihyd2 |
Domain d1ihyb1: 1ihy B:1-148,B:313-334 [71221] Other proteins in same PDB: d1ihya2, d1ihyb2, d1ihyc2, d1ihyd2 |
Domain d1ihyc1: 1ihy C:1-148,C:313-334 [71223] Other proteins in same PDB: d1ihya2, d1ihyb2, d1ihyc2, d1ihyd2 |
Domain d1ihyd1: 1ihy D:1-148,D:313-334 [71225] Other proteins in same PDB: d1ihya2, d1ihyb2, d1ihyc2, d1ihyd2 complexed with apr, so4 |
Domain d1szjg1: 1szj G:1-148,G:313-334 [30024] Other proteins in same PDB: d1szjg2, d1szjr2 |
Domain d1szjr1: 1szj R:1-148,R:313-334 [30025] Other proteins in same PDB: d1szjg2, d1szjr2 complexed with nad, so4 |
Spinach (Spinacia oleracea) [TaxId:3562] [69409] (1 PDB entry) |
Domain d1jn0a1: 1jn0 A:0-148,A:313-333 [66915] Other proteins in same PDB: d1jn0a2, d1jn0b2, d1jn0o2 |
Domain d1jn0b1: 1jn0 B:0-148,B:313-333 [66917] Other proteins in same PDB: d1jn0a2, d1jn0b2, d1jn0o2 complexed with ndp, so4 |
Domain d1jn0o1: 1jn0 O:0-148,O:313-333 [66919] Other proteins in same PDB: d1jn0a2, d1jn0b2, d1jn0o2 |
Thermotoga maritima [TaxId:243274] [51805] (1 PDB entry) |
Domain d1hdgo1: 1hdg O:1-148,O:313-331 [29990] Other proteins in same PDB: d1hdgo2, d1hdgq2 |
Domain d1hdgq1: 1hdg Q:1-148,Q:313-331 [29991] Other proteins in same PDB: d1hdgo2, d1hdgq2 complexed with nad, so4 |
Thermus aquaticus [TaxId:271] [51804] (1 PDB entry) |
Domain d1cero1: 1cer O:1-148,O:313-333 [29986] Other proteins in same PDB: d1cero2, d1cerp2, d1cerq2, d1cerr2 |
Domain d1cerp1: 1cer P:1-148,P:313-333 [29988] Other proteins in same PDB: d1cero2, d1cerp2, d1cerq2, d1cerr2 |
Domain d1cerq1: 1cer Q:1-148,Q:313-333 [29987] Other proteins in same PDB: d1cero2, d1cerp2, d1cerq2, d1cerr2 |
Domain d1cerr1: 1cer R:1-148,R:313-333 [29989] Other proteins in same PDB: d1cero2, d1cerp2, d1cerq2, d1cerr2 complexed with nad |
Trypanosoma brucei brucei, glycosome [TaxId:5702] [51808] (1 PDB entry) |
Domain d1ggaa1: 1gga A:1-164,A:334-358 [30002] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 |
Domain d1ggab1: 1gga B:1-164,B:334-358 [30003] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 complexed with nad, so4 |
Domain d1ggao1: 1gga O:1-164,O:334-358 [29998] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 |
Domain d1ggap1: 1gga P:1-164,P:334-358 [29999] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 |
Domain d1ggaq1: 1gga Q:1-164,Q:334-358 [30000] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 |
Domain d1ggar1: 1gga R:1-164,R:334-358 [30001] Other proteins in same PDB: d1ggaa2, d1ggab2, d1ggao2, d1ggap2, d1ggaq2, d1ggar2 |
Trypanosoma cruzi [TaxId:5693] [75104] (1 PDB entry) |
Domain d1k3ta1: 1k3t A:1-164,A:334-359 [72022] Other proteins in same PDB: d1k3ta2, d1k3tb2, d1k3tc2, d1k3td2 |
Domain d1k3tb1: 1k3t B:1-164,B:334-359 [72024] Other proteins in same PDB: d1k3ta2, d1k3tb2, d1k3tc2, d1k3td2 |
Domain d1k3tc1: 1k3t C:1-164,C:334-359 [72026] Other proteins in same PDB: d1k3ta2, d1k3tb2, d1k3tc2, d1k3td2 |
Domain d1k3td1: 1k3t D:1-164,D:334-359 [72028] Other proteins in same PDB: d1k3ta2, d1k3tb2, d1k3tc2, d1k3td2 complexed with brz |
Timeline for Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain: