SCOPe 2.03: Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Lineage for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

Proteins:

1. 1-deoxy-D-xylulose-5-phosphate reductoisomerase [69410] (2 species)

   1. Species Escherichia coli [TaxId:562] [69411] (11 PDB entries)
      Uniprot P45568

   2. Species Zymomonas mobilis [TaxId:542] [110420] (2 PDB entries)
      Uniprot Q9X5F2

2. Acetaldehyde dehydrogenase (acylating) [89527] (1 species)

   • Species Pseudomonas sp. [TaxId:306] [89528] (1 PDB entry)

3. Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

   1. Species Escherichia coli [TaxId:562] [51814] (4 PDB entries)
      Uniprot P00353

   2. Species Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)
      Uniprot P44801

   3. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (11 PDB entries)
      Uniprot Q8DQ00 2-127,330-357

   4. Species Vibrio cholerae [TaxId:666] [82297] (4 PDB entries)

4. Biliverdin reductase [51823] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [51824] (3 PDB entries)

5. Diaminopimelic acid dehydrogenase (DAPDH) [51819] (1 species)

   • Species Corynebacterium glutamicum [TaxId:1718] [51820] (4 PDB entries)

6. Dihydrodipicolinate reductase [51821] (3 species)

   1. Species Escherichia coli [TaxId:562] [51822] (5 PDB entries)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [102160] (5 PDB entries)

   3. Species Thermotoga maritima [TaxId:2336] [110417] (1 PDB entry)
      Uniprot Q9X1K8

7. Galactose/lactose metabolism regulatory protein GAL80 [141921] (1 species)

   • Species Yeast (Kluyveromyces lactis) [TaxId:28985] [141922] (2 PDB entries)
     Uniprot Q06433 2-154,374-457

8. Glucose 6-phosphate dehydrogenase, N-terminal domain [51827] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [51829] (1 PDB entry)

   2. Species Leuconostoc mesenteroides [TaxId:1245] [51828] (9 PDB entries)

9. Glucose-fructose oxidoreductase, N-terminal domain [51825] (1 species)

   • Species Zymomonas mobilis [TaxId:542] [51826] (8 PDB entries)

10. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801] (19 species)

    1. Species Achromobacter xylosoxidans [TaxId:85698] [89526] (1 PDB entry)
       formerly Alcaligenes xylosoxidans

    2. Species American lobster (Homarus americanus) [TaxId:6706] [51810] (2 PDB entries)

    3. Species Bacillus stearothermophilus, nca 1503 [TaxId:1422] [51803] (11 PDB entries)

    4. Species Escherichia coli [TaxId:562] [51802] (9 PDB entries)
       Uniprot P06977

    5. Species Human (Homo sapiens) [TaxId:9606] [51812] (1 PDB entry)

    6. Species Human (Homo sapiens), liver isoform [TaxId:9606] [141915] (2 PDB entries)
       Uniprot P04406 2-150,315-334

    7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141916] (3 PDB entries)
       Uniprot Q8IKK7 4-152,319-335! Uniprot Q8T6B1 1-152,319-337

    8. Species Methanothermus fervidus [TaxId:2180] [51807] (1 PDB entry)

    9. Species Pyrococcus horikoshii [TaxId:53953] [159423] (1 PDB entry)
       Uniprot O59494 1-139,302-334

    10. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [102158] (1 PDB entry)

    11. Species South China Sea lobster (Palinurus versicolor) [TaxId:150436] [51811] (5 PDB entries)

    12. Species Spinach (Spinacia oleracea) [TaxId:3562] [69409] (8 PDB entries)
        Uniprot P19866

    13. Species Sulfolobus solfataricus [TaxId:2287] [51806] (1 PDB entry)

    14. Species Thermotoga maritima [TaxId:2336] [51805] (1 PDB entry)

    15. Species Thermus aquaticus [TaxId:271] [51804] (2 PDB entries)

    16. Species Thermus thermophilus [TaxId:274] [102157] (1 PDB entry)

    17. Species Trypanosoma brucei brucei, glycosome [TaxId:5702] [51808] (1 PDB entry)

    18. Species Trypanosoma cruzi [TaxId:5693] [75104] (5 PDB entries)

    19. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [51809] (5 PDB entries)

11. Homoserine dehydrogenase [51815] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51816] (4 PDB entries)
      Uniprot P31116

12. Hypothetical protein TM0312 [141925] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [141926] (1 PDB entry)
      Uniprot Q9WYE8 4-131,276-328

13. Hypothetical protein TM1419 [102161] (1 species)
    myo-inositol 1-phosphate synthase-related protein

    • Species Thermotoga maritima [TaxId:2336] [102162] (1 PDB entry)

14. Hypothetical protein TM1643 [75108] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [75109] (2 PDB entries)

15. Myo-inositol 1-phosphate synthase [75105] (4 species)

    1. Species Archaeoglobus fulgidus [TaxId:2234] [110418] (3 PDB entries)
       Uniprot O28480

    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75107] (9 PDB entries)
       Uniprot P11986

    3. Species Mycobacterium tuberculosis [TaxId:1773] [75106] (1 PDB entry)

    4. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [110419] (1 PDB entry)
       Uniprot Q18664

16. N-acetyl-gamma-glutamyl-phosphate reductase ArgC [110423] (3 species)

    1. Species Salmonella typhimurium [TaxId:90371] [141918] (1 PDB entry)
       Uniprot Q8ZKL8 1-153,309-334

    2. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117428] (2 PDB entries)
       Uniprot O82187 15-359

    3. Species Thermotoga maritima [TaxId:2336] [110424] (1 PDB entry)
       Uniprot Q9X2A2

17. Probable oxidoreductase At4g09670 [117429] (1 species)

    • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117430] (2 PDB entries)
      Uniprot Q9SZ83

18. Putative oxidoreductase VCA1048 [110425] (1 species)

    • Species Vibrio cholerae [TaxId:666] [110426] (1 PDB entry)
      Uniprot Q9KKQ4

19. Putative semialdehyde dehydrogenase [141919] (1 species)

    • Species Rice (Oryza sativa) [TaxId:4530] [141920] (1 PDB entry)
      Uniprot Q6AV34 68-218,384-415

20. Saccharopine reductase [51817] (1 species)

    • Species Fungus (Magnaporthe grisea) [TaxId:148305] [51818] (3 PDB entries)

21. Usg-1 protein homolog PA3116 [141923] (1 species)

    • Species Pseudomonas aeruginosa [TaxId:287] [141924] (1 PDB entry)
      Uniprot O87014 3-129,320-336

22. Virulence factor MviM [110421] (1 species)

    • Species Escherichia coli [TaxId:562] [110422] (1 PDB entry)
      Uniprot P75931

More info for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain:

• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOPe 2.02
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOPe 2.04
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.08