SCOP 1.73: Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

Lineage for Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Enoyl-ACP reductase [51791] (6 species)
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (19 PDB entries)

PDB entries in Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]:

Domain(s) for 1bvr:
1. Domain d1bvra_: 1bvr A: [29913]
2. Domain d1bvrb_: 1bvr B: [29914]
3. Domain d1bvrc_: 1bvr C: [29915]
4. Domain d1bvrd_: 1bvr D: [29916]
5. Domain d1bvre_: 1bvr E: [29917]
6. Domain d1bvrf_: 1bvr F: [29918]
  complexed with nad, tht
Domain(s) for 1eny:
- Domain d1enya_: 1eny A: [29910]
  complexed with nad
Domain(s) for 1enz:
- Domain d1enza_: 1enz A: [29912]
  complexed with nad; mutant
Domain(s) for 1p44:
1. Domain d1p44a_: 1p44 A: [94076]
2. Domain d1p44b_: 1p44 B: [94077]
3. Domain d1p44c_: 1p44 C: [94078]
4. Domain d1p44d_: 1p44 D: [94079]
5. Domain d1p44e_: 1p44 E: [94080]
6. Domain d1p44f_: 1p44 F: [94081]
  complexed with geq, nad
Domain(s) for 1p45:
1. Domain d1p45a_: 1p45 A: [94082]
2. Domain d1p45b_: 1p45 B: [94083]
  complexed with nad, tcl
Domain(s) for 1zid:
- Domain d1zida_: 1zid A: [29911]
  complexed with zid; mutant
Domain(s) for 2aq8:
- Domain d2aq8a1: 2aq8 A:3-269 [127166]
  automatically matched to d1bvra_
  complexed with lys, nad
Domain(s) for 2aqk:
- Domain d2aqka1: 2aqk A:3-269 [127181]
  automatically matched to d1enz__
  complexed with nad; mutant
Domain(s) for 2b35:
1. Domain d2b35a1: 2b35 A:2-269 [127767]
  automatically matched to d1bvra_
  complexed with nad, tcl
2. Domain d2b35b1: 2b35 B:2-269 [127768]
  automatically matched to d1bvra_
  complexed with nad, tcl
3. Domain d2b35c1: 2b35 C:2-269 [127769]
  automatically matched to d1bvra_
  complexed with nad, tcl
4. Domain d2b35d1: 2b35 D:2-269 [127770]
  automatically matched to d1bvra_
  complexed with nad, tcl
5. Domain d2b35e1: 2b35 E:2-269 [127771]
  automatically matched to d1bvra_
  complexed with nad, tcl
6. Domain d2b35f1: 2b35 F:2-269 [127772]
  automatically matched to d1bvra_
  complexed with nad, tcl
Domain(s) for 2b36:
1. Domain d2b36a1: 2b36 A:2-269 [127773]
  automatically matched to d1bvra_
  complexed with 5pp, nad
2. Domain d2b36b1: 2b36 B:2-269 [127774]
  automatically matched to d1bvra_
  complexed with 5pp, nad
3. Domain d2b36c1: 2b36 C:2-269 [127775]
  automatically matched to d1bvra_
  complexed with 5pp, nad
4. Domain d2b36d1: 2b36 D:2-269 [127776]
  automatically matched to d1bvra_
  complexed with 5pp, nad
5. Domain d2b36e1: 2b36 E:2-269 [127777]
  automatically matched to d1bvra_
  complexed with 5pp, nad
6. Domain d2b36f1: 2b36 F:2-269 [127778]
  automatically matched to d1bvra_
  complexed with 5pp, nad
Domain(s) for 2b37:
1. Domain d2b37a1: 2b37 A:2-269 [127779]
  automatically matched to d1bvra_
  complexed with 8ps, nad
2. Domain d2b37b1: 2b37 B:2-269 [127780]
  automatically matched to d1bvra_
  complexed with 8ps, nad
3. Domain d2b37c1: 2b37 C:2-269 [127781]
  automatically matched to d1bvra_
  complexed with 8ps, nad
4. Domain d2b37d1: 2b37 D:2-269 [127782]
  automatically matched to d1bvra_
  complexed with 8ps, nad
5. Domain d2b37e1: 2b37 E:2-269 [127783]
  automatically matched to d1bvra_
  complexed with 8ps, nad
6. Domain d2b37f1: 2b37 F:2-269 [127784]
  automatically matched to d1bvra_
  complexed with 8ps, nad
Domain(s) for 2h7i:
- Domain d2h7ia1: 2h7i A:2-269 [136215]
  automatically matched to d1bvra_
  complexed with 566, nad
Domain(s) for 2h7l:
- Domain d2h7la1: 2h7l A:2-269 [136218]
  automatically matched to d1bvra_
  complexed with 665, nad
Domain(s) for 2h7m:
- Domain d2h7ma1: 2h7m A:2-269 [136219]
  automatically matched to d1bvra_
  complexed with 641, nad
Domain(s) for 2h7n:
- Domain d2h7na1: 2h7n A:2-269 [136220]
  automatically matched to d1bvra_
  complexed with 744, nad
Domain(s) for 2h7p:
- Domain d2h7pa1: 2h7p A:2-269 [136221]
  automatically matched to d1bvra_
  complexed with 468, nad
Domain(s) for 2h9i:
- Domain d2h9ia1: 2h9i A:3-269 [136265]
  automatically matched to d1bvra_
  complexed with ead
Domain(s) for 2ntj:
1. Domain d2ntja1: 2ntj A:3-269 [138581]
  automatically matched to d1bvra_
  complexed with p1h; mutant
2. Domain d2ntjb1: 2ntj B:3-269 [138582]
  automatically matched to d1bvra_
  complexed with p1h; mutant
Domain(s) for 2nv6:
- Domain d2nv6a1: 2nv6 A:3-269 [138627]
  automatically matched to d1enz__
  complexed with zid; mutant

More info for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase

Timeline for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase:

Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase first appeared (with stable ids) in SCOP 1.55
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in SCOP 1.71
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in SCOP 1.75
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in the current release, SCOPe 2.08