SCOP 1.71: Protein: Enoyl-ACP reductase

Lineage for Protein: Enoyl-ACP reductase

Root: SCOP 1.71
Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (53 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Enoyl-ACP reductase [51791] (6 species)

Species:

Escherichia coli [TaxId:562] [51794] (12 PDB entries)
1. Domains for 1c14:
  1. Domain d1c14a_: 1c14 A: [29927]
  2. Domain d1c14b_: 1c14 B: [29928]
    complexed with nad, tcl
2. Domains for 1d8a:
  1. Domain d1d8aa_: 1d8a A: [29931]
  2. Domain d1d8ab_: 1d8a B: [29932]
3. Domains for 1dfg:
  1. Domain d1dfga_: 1dfg A: [29933]
  2. Domain d1dfgb_: 1dfg B: [29934]
    complexed with nad, ndt
4. Domains for 1dfh:
  1. Domain d1dfha_: 1dfh A: [29929]
  2. Domain d1dfhb_: 1dfh B: [29930]
    complexed with nad, tdb
5. Domains for 1dfi:
  1. Domain d1dfia_: 1dfi A: [29923]
  2. Domain d1dfib_: 1dfi B: [29924]
  3. Domain d1dfic_: 1dfi C: [29925]
  4. Domain d1dfid_: 1dfi D: [29926]
    complexed with nad
6. Domains for 1i2z:
  1. Domain d1i2za_: 1i2z A: [65989]
  2. Domain d1i2zb_: 1i2z B: [65990]
    complexed with 654, nad
7. Domains for 1i30:
  1. Domain d1i30a_: 1i30 A: [65991]
  2. Domain d1i30b_: 1i30 B: [65992]
    complexed with 826, nad
8. Domains for 1lx6:
  1. Domain d1lx6a_: 1lx6 A: [78287]
  2. Domain d1lx6b_: 1lx6 B: [78288]
    complexed with nad, zam
9. Domains for 1lxc:
  1. Domain d1lxca_: 1lxc A: [78289]
  2. Domain d1lxcb_: 1lxc B: [78290]
    complexed with aym, nad
10. Domains for 1mfp:
  1. Domain d1mfpa_: 1mfp A: [84938]
  2. Domain d1mfpb_: 1mfp B: [84939]
    complexed with idn, nad, so4
11. Domains for 1qg6:
  1. Domain d1qg6a_: 1qg6 A: [29919]
  2. Domain d1qg6b_: 1qg6 B: [29920]
  3. Domain d1qg6c_: 1qg6 C: [29921]
  4. Domain d1qg6d_: 1qg6 D: [29922]
    complexed with nad, tcl
12. Domains for 1qsg:
  1. Domain d1qsga_: 1qsg A: [29935]
  2. Domain d1qsgb_: 1qsg B: [29936]
  3. Domain d1qsgc_: 1qsg C: [29937]
  4. Domain d1qsgd_: 1qsg D: [29938]
  5. Domain d1qsge_: 1qsg E: [29939]
  6. Domain d1qsgf_: 1qsg F: [29940]
  7. Domain d1qsgg_: 1qsg G: [29941]
  8. Domain d1qsgh_: 1qsg H: [29942]
    complexed with glc, nad, tcs
Helicobacter pylori [TaxId:210] [102151] (2 PDB entries)
1. Domains for 1jvf:
  1. Domain d1jvfa_: 1jvf A: [90913]
  2. Domain d1jvfb_: 1jvf B: [90914]
  3. Domain d1jvfc_: 1jvf C: [90915]
  4. Domain d1jvfd_: 1jvf D: [90916]
    complexed with nad, tcl
2. Domains for 1jw7:
  1. Domain d1jw7a_: 1jw7 A: [90917]
  2. Domain d1jw7b_: 1jw7 B: [90918]
  3. Domain d1jw7c_: 1jw7 C: [90919]
  4. Domain d1jw7d_: 1jw7 D: [90920]
    complexed with dcn, nad
Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (6 PDB entries)
1. Domains for 1nhd:
  1. Domain d1nhd.1: 1nhd A:,C: [80510]
  2. Domain d1nhd.2: 1nhd B:,D: [80511]
    complexed with nad
2. Domains for 1nhg:
  1. Domain d1nhg.1: 1nhg A:,C: [80516]
  2. Domain d1nhg.2: 1nhg B:,D: [80517]
    complexed with nad, tcl
3. Domains for 1nhw:
  1. Domain d1nhw.1: 1nhw A:,C: [80518]
  2. Domain d1nhw.2: 1nhw B:,D: [80519]
    complexed with nad, tcc
4. Domains for 1nnu:
  1. Domain d1nnu.1: 1nnu A:,C: [80672]
  2. Domain d1nnu.2: 1nnu B:,D: [80673]
    complexed with nad, tct
5. Domains for 1uh5:
  1. Domain d1uh5a_: 1uh5 A: [107840]
  2. Domain d1uh5b_: 1uh5 B: [107841]
    complexed with nad, tcl
6. Domains for 1v35:
  1. Domain d1v35a_: 1v35 A: [108301]
  2. Domain d1v35b_: 1v35 B: [108302]
    complexed with nai
Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (6 PDB entries)
1. Domains for 1bvr:
  1. Domain d1bvra_: 1bvr A: [29913]
  2. Domain d1bvrb_: 1bvr B: [29914]
  3. Domain d1bvrc_: 1bvr C: [29915]
  4. Domain d1bvrd_: 1bvr D: [29916]
  5. Domain d1bvre_: 1bvr E: [29917]
  6. Domain d1bvrf_: 1bvr F: [29918]
    complexed with nad, tht
2. Domain for 1eny:
  - Domain d1eny__: 1eny - [29910]
    complexed with nad
3. Domain for 1enz:
  - Domain d1enz__: 1enz - [29912]
    complexed with nad; mutant
4. Domains for 1p44:
  1. Domain d1p44a_: 1p44 A: [94076]
  2. Domain d1p44b_: 1p44 B: [94077]
  3. Domain d1p44c_: 1p44 C: [94078]
  4. Domain d1p44d_: 1p44 D: [94079]
  5. Domain d1p44e_: 1p44 E: [94080]
  6. Domain d1p44f_: 1p44 F: [94081]
    complexed with geq, nad
5. Domains for 1p45:
  1. Domain d1p45a_: 1p45 A: [94082]
  2. Domain d1p45b_: 1p45 B: [94083]
    complexed with nad, tcl
6. Domain for 1zid:
  - Domain d1zid__: 1zid - [29911]
    complexed with zid; mutant
Oil seed rape (Brassica napus) [TaxId:3708] [51792] (4 PDB entries)
1. Domains for 1cwu:
  1. Domain d1cwua_: 1cwu A: [29908]
  2. Domain d1cwub_: 1cwu B: [29909]
    complexed with nad, tdb; mutant
2. Domain for 1d7o:
  - Domain d1d7oa_: 1d7o A: [29907]
3. Domain for 1eno:
  - Domain d1eno__: 1eno - [29905]
    complexed with nad; mutant
4. Domain for 1enp:
  - Domain d1enp__: 1enp - [29906]
    complexed with nah; mutant
scop new_sp Thermus thermophilus [117409] (1 PDB entry)
- Domains for 1ulu:
  1. Domain d1ulua_: 1ulu A: [113292]
  2. Domain d1ulub_: 1ulu B: [113293]
  3. Domain d1uluc_: 1ulu C: [113294]
  4. Domain d1ulud_: 1ulu D: [113295]

More info for Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared (with stable ids) in SCOP 1.55
Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.69
Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.73
Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in the current release, SCOPe 2.08