Lineage for Protein: Enoyl-ACP reductase

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 238223Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 238224Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families) (S)
  5. 238382Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (31 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 238544Protein Enoyl-ACP reductase [51791] (4 species)

Species:

  1. 238545Escherichia coli [TaxId:562] [51794] (11 PDB entries)
    1. Domains for 1c14:
      1. 238562Domain d1c14a_: 1c14 A: [29927]
      2. 238563Domain d1c14b_: 1c14 B: [29928]
        complexed with nad, tcl
    2. Domains for 1d8a:
      1. 238566Domain d1d8aa_: 1d8a A: [29931]
      2. 238567Domain d1d8ab_: 1d8a B: [29932]
    3. Domains for 1dfg:
      1. 238570Domain d1dfga_: 1dfg A: [29933]
      2. 238571Domain d1dfgb_: 1dfg B: [29934]
        complexed with nad, ndt
    4. Domains for 1dfh:
      1. 238564Domain d1dfha_: 1dfh A: [29929]
      2. 238565Domain d1dfhb_: 1dfh B: [29930]
        complexed with nad, tdb
    5. Domains for 1dfi:
      1. 238558Domain d1dfia_: 1dfi A: [29923]
      2. 238559Domain d1dfib_: 1dfi B: [29924]
      3. 238560Domain d1dfic_: 1dfi C: [29925]
      4. 238561Domain d1dfid_: 1dfi D: [29926]
        complexed with nad
    6. Domains for 1i2z:
      1. 238574Domain d1i2za_: 1i2z A: [65989]
      2. 238575Domain d1i2zb_: 1i2z B: [65990]
        complexed with 654, nad
    7. Domains for 1i30:
      1. 238572Domain d1i30a_: 1i30 A: [65991]
      2. 238573Domain d1i30b_: 1i30 B: [65992]
        complexed with 826, nad
    8. Domains for 1lx6:
      1. 238568Domain d1lx6a_: 1lx6 A: [78287]
      2. 238569Domain d1lx6b_: 1lx6 B: [78288]
        complexed with nad, zam
    9. Domains for 1lxc:
      1. 238576Domain d1lxca_: 1lxc A: [78289]
      2. 238577Domain d1lxcb_: 1lxc B: [78290]
        complexed with aym, nad
    10. Domains for 1qg6:
      1. 238554Domain d1qg6a_: 1qg6 A: [29919]
      2. 238555Domain d1qg6b_: 1qg6 B: [29920]
      3. 238556Domain d1qg6c_: 1qg6 C: [29921]
      4. 238557Domain d1qg6d_: 1qg6 D: [29922]
        complexed with nad, tcl
    11. Domains for 1qsg:
      1. 238546Domain d1qsga_: 1qsg A: [29935]
      2. 238547Domain d1qsgb_: 1qsg B: [29936]
      3. 238548Domain d1qsgc_: 1qsg C: [29937]
      4. 238549Domain d1qsgd_: 1qsg D: [29938]
      5. 238550Domain d1qsge_: 1qsg E: [29939]
      6. 238551Domain d1qsgf_: 1qsg F: [29940]
      7. 238552Domain d1qsgg_: 1qsg G: [29941]
      8. 238553Domain d1qsgh_: 1qsg H: [29942]
        complexed with glc, nad, tcs
  2. 238578Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (4 PDB entries)
    1. Domains for 1nhd:
      1. 238579Domain d1nhd.1: 1nhd A:,C: [80510]
      2. 238580Domain d1nhd.2: 1nhd B:,D: [80511]
        complexed with nad
    2. Domains for 1nhg:
      1. 238581Domain d1nhg.1: 1nhg A:,C: [80516]
      2. 238582Domain d1nhg.2: 1nhg B:,D: [80517]
        complexed with nad, tcl
    3. Domains for 1nhw:
      1. 238583Domain d1nhw.1: 1nhw A:,C: [80518]
      2. 238584Domain d1nhw.2: 1nhw B:,D: [80519]
        complexed with nad, tcc
    4. Domains for 1nnu:
      1. 238585Domain d1nnu.1: 1nnu A:,C: [80672]
      2. 238586Domain d1nnu.2: 1nnu B:,D: [80673]
        complexed with nad, tct
  3. 238587Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (4 PDB entries)
    1. Domains for 1bvr:
      1. 238591Domain d1bvra_: 1bvr A: [29913]
      2. 238592Domain d1bvrb_: 1bvr B: [29914]
      3. 238593Domain d1bvrc_: 1bvr C: [29915]
      4. 238594Domain d1bvrd_: 1bvr D: [29916]
      5. 238595Domain d1bvre_: 1bvr E: [29917]
      6. 238596Domain d1bvrf_: 1bvr F: [29918]
        complexed with nad, tht
    2. Domain for 1eny:
    3. Domain for 1enz:
    4. Domain for 1zid:
  4. 238597Oil seed rape (Brassica napus) [TaxId:3708] [51792] (4 PDB entries)
    1. Domains for 1cwu:
      1. 238601Domain d1cwua_: 1cwu A: [29908]
      2. 238602Domain d1cwub_: 1cwu B: [29909]
        complexed with nad, tdb; mutant
    2. Domain for 1d7o:
    3. Domain for 1eno:
    4. Domain for 1enp:

More info for Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Enoyl-ACP reductase from c.2.1.2: Tyrosine-dependent oxidoreductases: