SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Streptomyces hydrogenans [TaxId: 1905]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2090742Protein 3-alpha,20-beta-hydroxysteroid dehydrogenase [51776] (1 species)
  7. 2090743Species Streptomyces hydrogenans [TaxId:1905] [51777] (2 PDB entries)

PDB entries in Species: Streptomyces hydrogenans [TaxId: 1905]:

  1. Domain(s) for 1hdc:
    1. 2090744Domain d1hdca_: 1hdc A: [29862]
      complexed with cbo
    2. 2090745Domain d1hdcb_: 1hdc B: [29863]
      complexed with cbo
    3. 2090746Domain d1hdcc_: 1hdc C: [29864]
      complexed with cbo
    4. 2090747Domain d1hdcd_: 1hdc D: [29865]
      complexed with cbo
  2. Domain(s) for 2hsd:
    1. 2090748Domain d2hsda_: 2hsd A: [29866]
      complexed with nad
    2. 2090749Domain d2hsdb_: 2hsd B: [29867]
      complexed with nad
    3. 2090750Domain d2hsdc_: 2hsd C: [29868]
      complexed with nad
    4. 2090751Domain d2hsdd_: 2hsd D: [29869]
      complexed with nad

More info for Species Streptomyces hydrogenans [TaxId:1905] from c.2.1.2 3-alpha,20-beta-hydroxysteroid dehydrogenase

Timeline for Species Streptomyces hydrogenans [TaxId:1905] from c.2.1.2 3-alpha,20-beta-hydroxysteroid dehydrogenase: