Class c: Alpha and beta proteins (a/b) [51349] (134 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (53 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 |
Protein Human estrogenic 17beta-hydroxysteroid dehydrogenase [51772] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [51773] (16 PDB entries) |
Domain d1a27__: 1a27 - [29839] complexed with est, nap; mutant |
Domain d1bhs__: 1bhs - [29840] |
Domain d1dhta_: 1dht A: [29843] complexed with dht |
Domain d1equa_: 1equ A: [29846] |
Domain d1equb_: 1equ B: [29847] complexed with equ, ndp |
Domain d1fds__: 1fds - [29838] complexed with est |
Domain d1fdt__: 1fdt - [29841] complexed with est, nap, so4 |
Domain d1fdua_: 1fdu A: [29848] |
Domain d1fdub_: 1fdu B: [29849] |
Domain d1fduc_: 1fdu C: [29850] |
Domain d1fdud_: 1fdu D: [29851] complexed with est, nap, so4; mutant |
Domain d1fdva_: 1fdv A: [29852] |
Domain d1fdvb_: 1fdv B: [29853] |
Domain d1fdvc_: 1fdv C: [29854] |
Domain d1fdvd_: 1fdv D: [29855] complexed with nad, so4; mutant |
Domain d1fdw__: 1fdw - [29845] complexed with est; mutant |
Domain d1i5ra_: 1i5r A: [83668] complexed with gol, hyc |
Domain d1iol__: 1iol - [29842] complexed with est |
Domain d1jtva_: 1jtv A: [84230] complexed with gol, tes |
Domain d1qyva_: 1qyv A: [104659] complexed with gol, nap |
Domain d1qywa_: 1qyw A: [104660] complexed with 5sd, gol, nap |
Domain d1qyxa_: 1qyx A: [104661] complexed with asd, gol, nap |
Domain d3dhea_: 3dhe A: [29844] complexed with and |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 Human estrogenic 17beta-hydroxysteroid dehydrogenase: