Lineage for Protein: Sepiapterin reductase

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 975118Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 975119Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 975436Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 976348Protein Sepiapterin reductase [51767] (2 species)

Species:

  1. 976349Human (Homo sapiens) [TaxId:9606] [141874] (1 PDB entry)
    Uniprot P35270 5-261
  2. 976356Mouse (Mus musculus) [TaxId:10090] [51768] (3 PDB entries)
    1. Domain for 1nas:
    2. Domain for 1oaa:
    3. Domain for 1sep:

More info for Protein Sepiapterin reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Sepiapterin reductase from c.2.1.2: Tyrosine-dependent oxidoreductases: