Lineage for Protein: Sepiapterin reductase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2091660Protein Sepiapterin reductase [51767] (2 species)

Species:

  1. 2091661Human (Homo sapiens) [TaxId:9606] [141874] (6 PDB entries)
    Uniprot P35270 5-261
    1. Domains for 1z6z:
      1. 2091670Domain d1z6za1: 1z6z A:2-258 [124575]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        complexed with cl, nap, so4
      2. 2091671Domain d1z6zb2: 1z6z B:2-258 [124576]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        automated match to d1z6za1
        complexed with cl, nap, so4
      3. 2091672Domain d1z6zc2: 1z6z C:2-258 [124577]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        automated match to d1z6za1
        complexed with cl, nap, so4
      4. 2091673Domain d1z6zd2: 1z6z D:2-258 [124578]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        automated match to d1z6za1
        complexed with cl, nap, so4
      5. 2091674Domain d1z6ze2: 1z6z E:2-258 [124579]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        automated match to d1z6za1
        complexed with cl, nap, so4
      6. 2091675Domain d1z6zf2: 1z6z F:2-258 [124580]
        Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
        automated match to d1z6za1
        complexed with cl, nap, so4
    2. Domains for 4hwk:
      1. 2091662Domain d4hwka_: 4hwk A: [252530]
        automated match to d1z6za1
        complexed with gol, nap, peg, sfy, so4
      2. 2091663Domain d4hwkb_: 4hwk B: [252531]
        automated match to d1z6za1
        complexed with gol, nap, peg, sfy, so4
      3. 2091664Domain d4hwkc_: 4hwk C: [252532]
        automated match to d1z6za1
        complexed with gol, nap, peg, sfy, so4
      4. 2091665Domain d4hwkd_: 4hwk D: [252533]
        automated match to d1z6za1
        complexed with gol, nap, peg, sfy, so4
    3. Domains for 4j7u:
      1. 2091666Domain d4j7ua_: 4j7u A: [252835]
        automated match to d1z6za1
        complexed with gol, nap, peg, so4, ytz
      2. 2091667Domain d4j7ub_: 4j7u B: [252836]
        automated match to d1z6za1
        complexed with gol, nap, peg, so4, ytz
      3. 2091668Domain d4j7uc_: 4j7u C: [252837]
        automated match to d1z6za1
        complexed with gol, nap, peg, so4, ytz
      4. 2091669Domain d4j7ud_: 4j7u D: [252838]
        automated match to d1z6za1
        complexed with gol, nap, peg, so4, ytz
    4. Domains for 4j7x:
      1. 2091684Domain d4j7xa_: 4j7x A: [252839]
        automated match to d1z6za1
        complexed with gol, nap, peg, sas, so4
      2. 2091685Domain d4j7xb_: 4j7x B: [252840]
        automated match to d1z6za1
        complexed with gol, nap, peg, sas, so4
      3. 2091686Domain d4j7xf_: 4j7x F: [252841]
        automated match to d1z6za1
        complexed with gol, nap, peg, sas, so4
      4. 2091687Domain d4j7xj_: 4j7x J: [252842]
        automated match to d1z6za1
        complexed with gol, nap, peg, sas, so4
    5. Domains for 4xwy:
      1. 2091680Domain d4xwya_: 4xwy A: [274553]
        automated match to d1z6zb_
        complexed with 43o, ndp, so4
      2. 2091681Domain d4xwyb_: 4xwy B: [274554]
        automated match to d1z6zb_
        complexed with 43o, ndp, so4
      3. 2091682Domain d4xwyc_: 4xwy C: [274555]
        automated match to d1z6zb_
        complexed with 43o, ndp, so4
      4. 2091683Domain d4xwyd_: 4xwy D: [274556]
        automated match to d1z6zb_
        complexed with 43o, ndp, so4
    6. Domains for 4z3k:
      1. 2091676Domain d4z3ka_: 4z3k A: [279521]
        automated match to d1z6zb_
        complexed with 4kl, edo, nap, so4
      2. 2091677Domain d4z3kb_: 4z3k B: [279520]
        automated match to d1z6zb_
        complexed with 4kl, edo, nap, so4
      3. 2091678Domain d4z3kc_: 4z3k C: [279518]
        automated match to d1z6zb_
        complexed with 4kl, edo, nap, so4
      4. 2091679Domain d4z3kd_: 4z3k D: [279519]
        automated match to d1z6zb_
        complexed with 4kl, edo, nap, so4
  2. 2091688Mouse (Mus musculus) [TaxId:10090] [51768] (3 PDB entries)
    1. Domain for 1nas:
    2. Domain for 1oaa:
    3. Domain for 1sep:

More info for Protein Sepiapterin reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Sepiapterin reductase from c.2.1.2: Tyrosine-dependent oxidoreductases: