Lineage for Protein: Carbonyl reductase

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 819418Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 819419Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 819736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 819969Protein Carbonyl reductase [51765] (2 species)

Species:

  1. 819970Human (Homo sapiens) [TaxId:9606] [102144] (2 PDB entries)
    dicarbonyl/L-xylulose reductase
    1. Domains for 1pr9:
      1. 819971Domain d1pr9a_: 1pr9 A: [95060]
      2. 819972Domain d1pr9b_: 1pr9 B: [95061]
        complexed with 2hp, k, nap
    2. Domains for 1wnt:
      1. 819973Domain d1wnta1: 1wnt A:1-244 [121102]
        automatically matched to d1pr9a_
        complexed with nap
      2. 819974Domain d1wntb1: 1wnt B:1-244 [121103]
        automatically matched to d1pr9a_
        complexed with nap
      3. 819975Domain d1wntc1: 1wnt C:1-244 [121104]
        automatically matched to d1pr9a_
        complexed with nap
      4. 819976Domain d1wntd1: 1wnt D:1-244 [121105]
        automatically matched to d1pr9a_
        complexed with nap
  2. 819977Mouse (Mus musculus) [TaxId:10090] [51766] (1 PDB entry)

More info for Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases: