Lineage for Protein: GDP-mannose 4,6-dehydratase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2091402Protein GDP-mannose 4,6-dehydratase [51759] (4 species)

Species:

  1. 2091403Escherichia coli [TaxId:562] [51760] (1 PDB entry)
  2. 2091405Human (Homo sapiens) [TaxId:9606] [102135] (3 PDB entries)
    1. Domains for 1t2a:
      1. 2091406Domain d1t2aa_: 1t2a A: [99078]
        complexed with gdp, ndp
      2. 2091407Domain d1t2ab_: 1t2a B: [99079]
        complexed with gdp, ndp
      3. 2091408Domain d1t2ac_: 1t2a C: [99080]
        complexed with gdp, ndp
      4. 2091409Domain d1t2ad_: 1t2a D: [99081]
        complexed with gdp, ndp
    2. Domains for 5in4:
      1. 2278012Domain d5in4c1: 5in4 C:23-372 [321313]
        Other proteins in same PDB: d5in4a2, d5in4b2, d5in4c2, d5in4d2
        automated match to d1t2aa_
        complexed with 6ck, gdp, nap
      2. 2278014Domain d5in4d1: 5in4 D:23-372 [321315]
        Other proteins in same PDB: d5in4a2, d5in4b2, d5in4c2, d5in4d2
        automated match to d1t2aa_
        complexed with 6ck, gdp, nap
      3. 2278022Domain d5in4b1: 5in4 B:23-372 [321323]
        Other proteins in same PDB: d5in4a2, d5in4b2, d5in4c2, d5in4d2
        automated match to d1t2aa_
        complexed with 6ck, gdp, nap
      4. 2278078Domain d5in4a1: 5in4 A:23-372 [321379]
        Other proteins in same PDB: d5in4a2, d5in4b2, d5in4c2, d5in4d2
        automated match to d1t2aa_
        complexed with 6ck, gdp, nap
    3. Domains for 5in5:
      1. 2278026Domain d5in5c1: 5in5 C:23-372 [321327]
        Other proteins in same PDB: d5in5a2, d5in5b2, d5in5c2, d5in5d2
        automated match to d1t2aa_
        complexed with gdp, gfb, gol, nap
      2. 2278043Domain d5in5b1: 5in5 B:23-372 [321344]
        Other proteins in same PDB: d5in5a2, d5in5b2, d5in5c2, d5in5d2
        automated match to d1t2aa_
        complexed with gdp, gfb, gol, nap
      3. 2278107Domain d5in5a1: 5in5 A:23-372 [321408]
        Other proteins in same PDB: d5in5a2, d5in5b2, d5in5c2, d5in5d2
        automated match to d1t2aa_
        complexed with gdp, gfb, gol, nap
      4. 2278135Domain d5in5d1: 5in5 D:23-372 [321436]
        Other proteins in same PDB: d5in5a2, d5in5b2, d5in5c2, d5in5d2
        automated match to d1t2aa_
        complexed with gdp, gfb, gol, nap
  3. 2091410Pseudomonas aeruginosa [TaxId:287] [102134] (1 PDB entry)
  4. 2091415Thale cress (Arabidopsis thaliana) [TaxId:3702] [82289] (2 PDB entries)
    1. Domains for 1n7g:
      1. 2091418Domain d1n7ga_: 1n7g A: [80246]
        complexed with gdr, ndp
      2. 2091419Domain d1n7gb_: 1n7g B: [80247]
        complexed with gdr, ndp
      3. 2091420Domain d1n7gc_: 1n7g C: [80248]
        complexed with gdr, ndp
      4. 2091421Domain d1n7gd_: 1n7g D: [80249]
        complexed with gdr, ndp
    2. Domains for 1n7h:
      1. 2091416Domain d1n7ha_: 1n7h A: [80250]
        complexed with gdp, ndp
      2. 2091417Domain d1n7hb_: 1n7h B: [80251]
        complexed with gdp, ndp

More info for Protein GDP-mannose 4,6-dehydratase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein GDP-mannose 4,6-dehydratase from c.2.1.2: Tyrosine-dependent oxidoreductases: