SCOPe 2.05: Protein: dTDP-glucose 4,6-dehydratase (RmlB)

Lineage for Protein: dTDP-glucose 4,6-dehydratase (RmlB)

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

Species:

Escherichia coli [TaxId:562] [51756] (1 PDB entry)
- Domains for 1bxk:
  1. Domain d1bxka_: 1bxk A: [29803]
    complexed with nad
  2. Domain d1bxkb_: 1bxk B: [29804]
    complexed with nad
Salmonella enterica [TaxId:28901] [63925] (1 PDB entry)
- Domains for 1g1a:
  1. Domain d1g1aa_: 1g1a A: [60198]
    complexed with nad, so4
  2. Domain d1g1ab_: 1g1a B: [60199]
    complexed with nad, so4
  3. Domain d1g1ac_: 1g1a C: [60200]
    complexed with nad, so4
  4. Domain d1g1ad_: 1g1a D: [60201]
    complexed with nad, so4
Streptococcus suis, serotype 2 [TaxId:1307] [69406] (6 PDB entries)
1. Domains for 1kep:
  1. Domain d1kepa_: 1kep A: [68536]
    complexed with nad, so4, tdx
  2. Domain d1kepb_: 1kep B: [68537]
    complexed with nad, so4, tdx
2. Domains for 1ker:
  1. Domain d1kera_: 1ker A: [68538]
    complexed with dau, nad, so4
  2. Domain d1kerb_: 1ker B: [68539]
    complexed with dau, nad, so4
3. Domains for 1ket:
  1. Domain d1keta_: 1ket A: [68540]
    complexed with nad, tyd
  2. Domain d1ketb_: 1ket B: [68541]
    complexed with nad, tyd
4. Domains for 1keu:
  1. Domain d1keua_: 1keu A: [68542]
    complexed with dau, nad
  2. Domain d1keub_: 1keu B: [68543]
    complexed with dau, nad
5. Domains for 1kew:
  1. Domain d1kewa_: 1kew A: [68544]
    complexed with gol, nad, tyd
  2. Domain d1kewb_: 1kew B: [68545]
    complexed with gol, nad, tyd
6. Domains for 1oc2:
  1. Domain d1oc2a_: 1oc2 A: [92765]
    complexed with nad, so4, tdx
  2. Domain d1oc2b_: 1oc2 B: [92766]
    complexed with nad, so4, tdx
Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries)
1. Domain for 1r66:
  - Domain d1r66a_: 1r66 A: [97146]
    complexed with cl, nad, tyd
2. Domain for 1r6d:
  - Domain d1r6da_: 1r6d A: [97148]
    complexed with dau, nad; mutant

More info for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared (with stable ids) in SCOP 1.55, called Protein dTDP-glucose 4,6-dehydratase from c.2.1.2: Tyrosine-dependent oxidoreductases
Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOPe 2.04
Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOPe 2.06
Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases appears in the current release, SCOPe 2.08