Lineage for Protein: dTDP-glucose 4,6-dehydratase (RmlB)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 819418Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 819419Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 819736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 820122Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

Species:

  1. 820123Escherichia coli [TaxId:562] [51756] (1 PDB entry)
  2. 820126Salmonella enterica [TaxId:28901] [63925] (1 PDB entry)
  3. 820131Streptococcus suis, serotype 2 [TaxId:1307] [69406] (6 PDB entries)
    1. Domains for 1kep:
      1. 820134Domain d1kepa_: 1kep A: [68536]
      2. 820135Domain d1kepb_: 1kep B: [68537]
        complexed with nad, so4, tdx
    2. Domains for 1ker:
      1. 820140Domain d1kera_: 1ker A: [68538]
      2. 820141Domain d1kerb_: 1ker B: [68539]
        complexed with dau, nad, so4
    3. Domains for 1ket:
      1. 820136Domain d1keta_: 1ket A: [68540]
      2. 820137Domain d1ketb_: 1ket B: [68541]
        complexed with nad, tyd
    4. Domains for 1keu:
      1. 820142Domain d1keua_: 1keu A: [68542]
      2. 820143Domain d1keub_: 1keu B: [68543]
        complexed with dau, nad
    5. Domains for 1kew:
      1. 820138Domain d1kewa_: 1kew A: [68544]
      2. 820139Domain d1kewb_: 1kew B: [68545]
        complexed with gol, nad, tyd
    6. Domains for 1oc2:
      1. 820132Domain d1oc2a_: 1oc2 A: [92765]
      2. 820133Domain d1oc2b_: 1oc2 B: [92766]
        complexed with nah, so4, tdx
  4. 820144Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries)
    1. Domain for 1r66:
    2. Domain for 1r6d:

More info for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases: