SCOP 1.67: Protein: Ketose reductase (sorbitol dehydrogenase)

Lineage for Protein: Ketose reductase (sorbitol dehydrogenase)

Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families)
Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (12 proteins)
N-terminal all-beta domain defines family
Protein Ketose reductase (sorbitol dehydrogenase) [51745] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [102130] (3 PDB entries)
1. Domains for 1pl6:
  1. Domain d1pl6a2: 1pl6 A:146-316 [94863]
    Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1
  2. Domain d1pl6b2: 1pl6 B:146-316 [94865]
    Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1
  3. Domain d1pl6c2: 1pl6 C:146-316 [94867]
    Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1
  4. Domain d1pl6d2: 1pl6 D:146-316 [94869]
    Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1
    complexed with 572, nad, zn
2. Domains for 1pl7:
  1. Domain d1pl7a2: 1pl7 A:146-316 [94871]
    Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1
  2. Domain d1pl7b2: 1pl7 B:146-316 [94873]
    Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1
  3. Domain d1pl7c2: 1pl7 C:146-316 [94875]
    Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1
  4. Domain d1pl7d2: 1pl7 D:146-316 [94877]
    Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1
    complexed with zn
3. Domains for 1pl8:
  1. Domain d1pl8a2: 1pl8 A:146-316 [94879]
    Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1
  2. Domain d1pl8b2: 1pl8 B:146-316 [94881]
    Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1
  3. Domain d1pl8c2: 1pl8 C:146-316 [94883]
    Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1
  4. Domain d1pl8d2: 1pl8 D:146-316 [94885]
    Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1
    complexed with nad, zn
Silverleaf whitefly (Bemisia argentifolii) [TaxId:77855] [51746] (1 PDB entry)
- Domain for 1e3j:
  - Domain d1e3ja2: 1e3j A:143-312 [29781]
    Other proteins in same PDB: d1e3ja1
    CASP4
    complexed with bo3, po4, zn

More info for Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain

Timeline for Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain:

Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain first appeared (with stable ids) in SCOP 1.55, called Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain
Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in SCOP 1.65
Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in SCOP 1.69
Protein Ketose reductase (sorbitol dehydrogenase) from c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain appears in the current release, SCOPe 2.08