Lineage for Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 975118Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 975119Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 975120Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (16 proteins)
    N-terminal all-beta domain defines family

Proteins:

  1. 9751212,4-dienoyl-CoA reductase [89517] (1 species)
  2. 975138Alcohol dehydrogenase [51737] (9 species)
    1. 975139Species Aeropyrum pernix [TaxId:56636] [102121] (1 PDB entry)
    2. 975142Species Bacillus stearothermophilus [TaxId:1422] [102123] (1 PDB entry)
    3. 975147Species Cod (Gadus callarias) [TaxId:8053] [51741] (1 PDB entry)
    4. 975150Species Frog (Rana perezi) [TaxId:8403] [89511] (2 PDB entries)
    5. 975155Species Horse (Equus caballus) [TaxId:9796] [51738] (36 PDB entries)
      Uniprot P00327
    6. 975233Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (24 PDB entries)
      Uniprot P00326 ! Uniprot P00325 ! Uniprot P07327
    7. 975288Species Mouse (Mus musculus), class II [TaxId:10090] [51740] (3 PDB entries)
    8. 975295Species Pseudomonas aeruginosa [TaxId:287] [102122] (1 PDB entry)
    9. 975304Species Sulfolobus solfataricus [TaxId:2287] [82286] (4 PDB entries)
  3. 975315B. subtilis YhfP homologue [117403] (1 species)
  4. 975319Bacterial secondary alcohol dehydrogenase [51742] (2 species)
    1. 975320Species Clostridium beijerinckii [TaxId:1520] [51743] (3 PDB entries)
    2. 975333Species Thermoanaerobacter brockii [TaxId:29323] [51744] (4 PDB entries)
  5. 975350Benzyl alcohol dehydrogenase [89512] (1 species)
  6. 975353Cinnamyl alcohol dehydrogenase, ADH6 [110403] (1 species)
  7. 975359Formaldehyde dehydrogenase [82287] (1 species)
  8. 975363Hypothetical protein TM0436 [102124] (1 species)
  9. 975369Hypothetical protein YahK [102128] (1 species)
  10. 975372Hypothetical protein YhdH [102126] (1 species)
  11. 975379Hypothetical protein YhfP [117405] (1 species)
  12. 975393Ketose reductase (sorbitol dehydrogenase) [51745] (2 species)
    1. 975394Species Human (Homo sapiens) [TaxId:9606] [102130] (3 PDB entries)
    2. 975407Species Silverleaf whitefly (Bemisia argentifolii) [TaxId:77855] [51746] (1 PDB entry)
  13. 975409Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110405] (1 species)
  14. 975419Putative enoyl reductase domain of polyketide synthase [89515] (1 species)
  15. 975423Putative zinc-binding alcohol dehydrogenase [102131] (1 species)
  16. 975426Quinone oxidoreductase [51747] (3 species)
    1. 975427Species Escherichia coli [TaxId:562] [51748] (1 PDB entry)
    2. 975430Species Human (Homo sapiens) [TaxId:9606] [117402] (1 PDB entry)
      Uniprot Q08257
    3. 975433Species Thermus thermophilus [TaxId:274] [89514] (2 PDB entries)

More info for Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain

Timeline for Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain: