SCOP 1.63: Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain

Lineage for Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)

5. Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain [51736] (6 proteins)
   N-terminal all-beta domain defines family

Proteins:

1. Alcohol dehydrogenase [51737] (5 species)

   1. Species Archaeon Sulfolobus solfataricus [TaxId:2287] [82286] (1 PDB entry)

   2. Species Cod (Gadus callarias) [TaxId:8053] [51741] (1 PDB entry)

   3. Species Horse (Equus caballus) [TaxId:9796] [51738] (30 PDB entries)

   4. Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (17 PDB entries)

   5. Species Mouse (Mus musculus), class II [TaxId:10090] [51740] (3 PDB entries)

2. Bacterial secondary alcohol dehydrogenase [51742] (2 species)

   1. Species Clostridium beijerinckii [51743] (3 PDB entries)

   2. Species Thermoanaerobacter brockii [TaxId:29323] [51744] (2 PDB entries)

3. Formaldehyde dehydrogenase [82287] (1 species)

   • Species Pseudomonas putida [TaxId:303] [82288] (1 PDB entry)

4. Glucose dehydrogenase [51749] (1 species)

   • Species Archaeon Thermoplasma acidophilum [TaxId:2303] [51750] (1 PDB entry)

5. Ketose reductase (sorbitol dehydrogenase) [51745] (1 species)

   • Species Silverleaf whitefly (Bemisia argentifolii) [TaxId:77855] [51746] (1 PDB entry)

6. Quinone oxidoreductase [51747] (1 species)

   • Species Escherichia coli [TaxId:562] [51748] (1 PDB entry)

More info for Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain

Timeline for Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain:

• Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain appears in SCOP 1.61
  
• Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain is called Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain in SCOP 1.65
  
• Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain appears in the current release, SCOPe 2.08, called Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain