Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.23: FAD-linked oxidoreductase [51730] (2 families) distinct cofactor-binding mode from both FMN- and NAD(P)-linked TIM-barrel oxidoreductases; families are related by a circular permutation |
Family c.1.23.1: Methylenetetrahydrofolate reductase [51731] (2 proteins) automatically mapped to Pfam PF02219 |
Protein Methylenetetrahydrofolate reductase [51732] (2 species) |
Species Escherichia coli [TaxId:562] [51733] (7 PDB entries) |
Domain d1b5ta_: 1b5t A: [29676] complexed with fad, hg |
Domain d1b5tb_: 1b5t B: [29677] complexed with fad, hg |
Domain d1b5tc_: 1b5t C: [29678] complexed with fad, hg |
Domain d1zp3a_: 1zp3 A: [203352] automated match to d1b5tb_ complexed with fad, mpd, so4 |
Domain d1zp3b_: 1zp3 B: [203353] automated match to d1b5tb_ complexed with fad, mpd, so4 |
Domain d1zp3c_: 1zp3 C: [203354] automated match to d1b5tb_ complexed with fad, mpd, so4 |
Domain d1zp4a_: 1zp4 A: [203355] automated match to d1b5tb_ complexed with c2f, fad, so4; mutant |
Domain d1zp4b_: 1zp4 B: [203356] automated match to d1b5tb_ complexed with c2f, fad, so4; mutant |
Domain d1zp4c_: 1zp4 C: [203357] automated match to d1b5tb_ complexed with c2f, fad, so4; mutant |
Domain d1zpta_: 1zpt A: [203358] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d1zptb_: 1zpt B: [203359] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d1zptc_: 1zpt C: [203360] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d1zrqa_: 1zrq A: [203361] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d1zrqb_: 1zrq B: [203362] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d1zrqc_: 1zrq C: [203363] automated match to d1b5tb_ complexed with fad, nai, so4 |
Domain d2fmna_: 2fmn A: [204229] automated match to d1b5tb_ complexed with 4hf, fad; mutant |
Domain d2fmnb_: 2fmn B: [204230] automated match to d1b5tb_ complexed with 4hf, fad; mutant |
Domain d2fmnc_: 2fmn C: [204231] automated match to d1b5tb_ complexed with 4hf, fad; mutant |
Domain d2fmoa_: 2fmo A: [204232] automated match to d1b5tb_ complexed with fad, mpd, so4; mutant |
Domain d2fmob_: 2fmo B: [204233] automated match to d1b5tb_ complexed with fad, mpd, so4; mutant |
Domain d2fmoc_: 2fmo C: [204234] automated match to d1b5tb_ complexed with fad, mpd, so4; mutant |
Timeline for Species Escherichia coli [TaxId:562] from c.1.23.1 Methylenetetrahydrofolate reductase: