Lineage for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2089476Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes [51703] (4 families) (S)


  1. 2089477c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain [51704] (2 protein domains)
    the subunits are clearly related but only one (alpha) is active
    automatically mapped to Pfam PF01642
  2. 2089512c.1.19.2: Glutamate mutase, large subunit [51707] (1 protein)
    automatically mapped to Pfam PF06368
  3. 2089521c.1.19.3: Diol dehydratase, alpha subunit [51710] (2 protein domains)
    automatically mapped to Pfam PF02286
  4. 2089547c.1.19.4: D-lysine 5,6-aminomutase alpha subunit, KamD [117392] (1 protein)
    most similar to the glutamate mutase subunit; contains second cofactor, PLP
    automatically mapped to Pfam PF09043

More info for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

Timeline for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes: