Lineage for Protein: 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 681098Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 683918Superfamily c.1.10: Aldolase [51569] (8 families) (S)
    Common fold covers whole protein structure
  5. 684412Family c.1.10.4: Class I DAHP synthetase [51599] (2 proteins)
  6. 684493Protein 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) [51602] (3 species)

Species:

  1. 684494Aquifex aeolicus [TaxId:63363] [63922] (18 PDB entries)
    1. Domains for 1fwn:
      1. 684521Domain d1fwna_: 1fwn A: [60060]
      2. 684522Domain d1fwnb_: 1fwn B: [60061]
        complexed with pep, po4
    2. Domains for 1fws:
      1. 684513Domain d1fwsa_: 1fws A: [60063]
      2. 684514Domain d1fwsb_: 1fws B: [60064]
        complexed with cd, pep, po4
    3. Domains for 1fwt:
      1. 684515Domain d1fwta_: 1fwt A: [60065]
      2. 684516Domain d1fwtb_: 1fwt B: [60066]
        complexed with cd, e4p, pep, po4
    4. Domains for 1fww:
      1. 684517Domain d1fwwa_: 1fww A: [60067]
      2. 684518Domain d1fwwb_: 1fww B: [60068]
        complexed with a5p, cd, pep, po4
    5. Domains for 1fx6:
      1. 684529Domain d1fx6a_: 1fx6 A: [60086]
      2. 684530Domain d1fx6b_: 1fx6 B: [60087]
        complexed with po4
    6. Domains for 1fxp:
      1. 684507Domain d1fxpa_: 1fxp A: [60106]
      2. 684508Domain d1fxpb_: 1fxp B: [60107]
        complexed with cd, po4
    7. Domains for 1fxq:
      1. 684509Domain d1fxqa_: 1fxq A: [60108]
      2. 684510Domain d1fxqb_: 1fxq B: [60109]
        complexed with a5p, pep
    8. Domains for 1fy6:
      1. 684523Domain d1fy6a_: 1fy6 A: [60111]
      2. 684524Domain d1fy6b_: 1fy6 B: [60112]
        complexed with a5p, cd, po4
    9. Domains for 1jcx:
      1. 684499Domain d1jcxa_: 1jcx A: [66510]
      2. 684500Domain d1jcxb_: 1jcx B: [66511]
        complexed with cd, pai
    10. Domains for 1jcy:
      1. 684519Domain d1jcya_: 1jcy A: [66512]
      2. 684520Domain d1jcyb_: 1jcy B: [66513]
        complexed with cd, pep, po4, r5p
    11. Domains for 1lrn:
      1. 684527Domain d1lrna_: 1lrn A: [78159]
      2. 684528Domain d1lrnb_: 1lrn B: [78160]
        complexed with cd, po4; mutant
    12. Domains for 1lro:
      1. 684501Domain d1lroa_: 1lro A: [78161]
      2. 684502Domain d1lrob_: 1lro B: [78162]
        complexed with cd, pep, po4; mutant
    13. Domains for 1lrq:
      1. 684503Domain d1lrqa_: 1lrq A: [78163]
      2. 684504Domain d1lrqb_: 1lrq B: [78164]
        complexed with a5p, cd, pep, po4; mutant
    14. Domains for 1pck:
      1. 684505Domain d1pcka_: 1pck A: [94438]
      2. 684506Domain d1pckb_: 1pck B: [94439]
        complexed with cd, pez, po4
    15. Domains for 1pcw:
      1. 684511Domain d1pcwa_: 1pcw A: [94495]
      2. 684512Domain d1pcwb_: 1pcw B: [94496]
        complexed with cd, h4p
    16. Domains for 1pe1:
      1. 684495Domain d1pe1a_: 1pe1 A: [94591]
      2. 684496Domain d1pe1b_: 1pe1 B: [94592]
        complexed with 2pg, cd, po4
    17. Domains for 2a21:
      1. 684497Domain d2a21a1: 2a21 A:1002-1264 [126023]
        automatically matched to d1pe1a_
        complexed with pep, po4, zn
      2. 684498Domain d2a21b1: 2a21 B:2003-2264 [126024]
        automatically matched to d1pe1a_
        complexed with pep, po4, zn
    18. Domains for 2a2i:
      1. 684525Domain d2a2ia1: 2a2i A:1002-1264 [126031]
        automatically matched to d1pe1a_
        complexed with a5p, pep, zn
      2. 684526Domain d2a2ib1: 2a2i B:2003-2264 [126032]
        automatically matched to d1pe1a_
        complexed with a5p, pep, zn
  2. 684531Escherichia coli [TaxId:562] [51603] (10 PDB entries)
    1. Domains for 1d9e:
      1. 684532Domain d1d9ea_: 1d9e A: [29195]
      2. 684533Domain d1d9eb_: 1d9e B: [29196]
      3. 684534Domain d1d9ec_: 1d9e C: [29197]
      4. 684535Domain d1d9ed_: 1d9e D: [29198]
        complexed with so4
    2. Domain for 1g7u:
    3. Domain for 1g7v:
    4. Domain for 1gg0:
    5. Domain for 1phq:
    6. Domain for 1phw:
    7. Domain for 1pl9:
    8. Domain for 1q3n:
    9. Domain for 1x6u:
    10. Domain for 1x8f:
  3. 684545Haemophilus influenzae [TaxId:727] [102095] (1 PDB entry)

More info for Protein 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) from c.1.10.4: Class I DAHP synthetase

Timeline for Protein 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) from c.1.10.4: Class I DAHP synthetase: