Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.10: Aldolase [51569] (9 families) Common fold covers whole protein structure |
Family c.1.10.1: Class I aldolase [51570] (13 proteins) the catalytic lysine forms schiff-base intermediate with substrate possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels |
Protein Fructose-1,6-bisphosphate aldolase [51576] (11 species) |
Fruit fly (Drosophila melanogaster) [TaxId:7227] [51579] (1 PDB entry) |
Domain d1fbaa_: 1fba A: [29120] |
Domain d1fbab_: 1fba B: [29121] |
Domain d1fbac_: 1fba C: [29122] |
Domain d1fbad_: 1fba D: [29123] |
Human (Homo sapiens) [TaxId:9606] [254964] (6 PDB entries) |
Domain d1xdlb_: 1xdl B: [121873] automated match to d1fdja_ complexed with so4 |
Domain d1xdlc_: 1xdl C: [121874] automated match to d1fdja_ complexed with so4 |
Domain d1xdld_: 1xdl D: [121875] automated match to d1fdja_ complexed with so4 |
Domain d1xdlw_: 1xdl W: [121876] automated match to d1fdja_ complexed with so4 |
Domain d1xdlx_: 1xdl X: [121877] automated match to d1fdja_ complexed with so4 |
Domain d1xdly_: 1xdl Y: [121878] automated match to d1fdja_ complexed with so4 |
Domain d1xdlz_: 1xdl Z: [121879] automated match to d1fdja_ complexed with so4 |
Domain d1xdma_: 1xdm A: [121880] automated match to d1fdja_ complexed with so4 |
Domain d1xdmb_: 1xdm B: [121881] automated match to d1fdja_ complexed with so4 |
Domain d1xdmc_: 1xdm C: [121882] automated match to d1fdja_ complexed with so4 |
Domain d1xdmd_: 1xdm D: [121883] automated match to d1fdja_ complexed with so4 |
Domain d1xdmw_: 1xdm W: [121884] automated match to d1fdja_ complexed with so4 |
Domain d1xdmx_: 1xdm X: [121885] automated match to d1fdja_ complexed with so4 |
Domain d1xdmy_: 1xdm Y: [121886] automated match to d1fdja_ complexed with so4 |
Domain d1xdmz_: 1xdm Z: [121887] automated match to d1fdja_ complexed with so4 |
Domain d6xmha_: 6xmh A: [417088] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmhb_: 6xmh B: [417089] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmla_: 6xml A: [417090] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmlb_: 6xml B: [417091] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmma_: 6xmm A: [417092] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmmb_: 6xmm B: [417093] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmoa_: 6xmo A: [417095] automated match to d1ewda_ complexed with gol, po4 |
Domain d6xmob_: 6xmo B: [417096] automated match to d1ewda_ complexed with gol, po4 |
Human (Homo sapiens), brain isozyme [TaxId:9606] [141834] (1 PDB entry) Uniprot P09972 2-343 |
Human (Homo sapiens), liver isozyme [TaxId:9606] [51578] (2 PDB entries) |
Domain d1qo5a_: 1qo5 A: [29102] complexed with so4 |
Domain d1qo5b_: 1qo5 B: [29103] complexed with so4 |
Domain d1qo5c_: 1qo5 C: [29104] complexed with so4 |
Domain d1qo5d_: 1qo5 D: [29105] complexed with so4 |
Domain d1qo5e_: 1qo5 E: [29106] complexed with so4 |
Domain d1qo5f_: 1qo5 F: [29107] complexed with so4 |
Domain d1qo5g_: 1qo5 G: [29108] complexed with so4 |
Domain d1qo5h_: 1qo5 H: [29109] complexed with so4 |
Domain d1qo5i_: 1qo5 I: [29110] complexed with so4 |
Domain d1qo5j_: 1qo5 J: [29111] complexed with so4 |
Domain d1qo5k_: 1qo5 K: [29112] complexed with so4 |
Domain d1qo5l_: 1qo5 L: [29113] complexed with so4 |
Domain d1qo5m_: 1qo5 M: [29114] complexed with so4 |
Domain d1qo5n_: 1qo5 N: [29115] complexed with so4 |
Domain d1qo5o_: 1qo5 O: [29116] complexed with so4 |
Domain d1qo5p_: 1qo5 P: [29117] complexed with so4 |
Domain d1qo5q_: 1qo5 Q: [29118] complexed with so4 |
Domain d1qo5r_: 1qo5 R: [29119] complexed with so4 |
Domain d1xdla1: 1xdl A:6-343 [121872] complexed with so4 |
Human (Homo sapiens), muscle isozyme [TaxId:9606] [51577] (4 PDB entries) |
Domain d1alda_: 1ald A: [29100] |
Domain d2alda_: 2ald A: [29099] |
Domain d4alda_: 4ald A: [29101] complexed with 2fp |
Domain d5ky6a_: 5ky6 A: [336081] automated match to d2alda_ |
Domain d5ky6b_: 5ky6 B: [336096] automated match to d2alda_ |
Domain d5ky6c_: 5ky6 C: [336017] automated match to d2alda_ |
Domain d5ky6d_: 5ky6 D: [336056] automated match to d2alda_ |
Malaria parasite (Plasmodium falciparum) [TaxId:5833] [51581] (1 PDB entry) |
Domain d1a5ca_: 1a5c A: [29148] |
Domain d1a5cb_: 1a5c B: [29149] |
Plasmodium yoelii yoelii [TaxId:73239] [141833] (1 PDB entry) Uniprot Q7RMC9 3-258 |
Domain d2a4aa1: 2a4a A:3-258 [126150] |
Domain d2a4ab_: 2a4a B: [126151] automated match to d2a4aa1 |
Rabbit (Oryctolagus cuniculus), liver isozyme [TaxId:9986] [63920] (1 PDB entry) |
Domain d1fdja_: 1fdj A: [59772] complexed with 13p, 2fp, g3p, so4 |
Domain d1fdjb_: 1fdj B: [59773] complexed with 13p, 2fp, g3p, so4 |
Domain d1fdjc_: 1fdj C: [59774] complexed with 13p, 2fp, g3p, so4 |
Domain d1fdjd_: 1fdj D: [59775] complexed with 13p, 2fp, g3p, so4 |
Rabbit (Oryctolagus cuniculus), muscle isozyme [TaxId:9986] [51580] (33 PDB entries) |
Domain d1adoa_: 1ado A: [29124] complexed with 13p, so4 |
Domain d1adob_: 1ado B: [29125] complexed with 13p, so4 |
Domain d1adoc_: 1ado C: [29126] complexed with 13p, so4 |
Domain d1adod_: 1ado D: [29127] complexed with 13p, so4 |
Domain d1ewda_: 1ewd A: [29132] |
Domain d1ewdb_: 1ewd B: [29133] |
Domain d1ewdc_: 1ewd C: [29134] |
Domain d1ewdd_: 1ewd D: [29135] |
Domain d1ewea_: 1ewe A: [29136] complexed with so4 |
Domain d1eweb_: 1ewe B: [29137] complexed with so4 |
Domain d1ewec_: 1ewe C: [29138] complexed with so4 |
Domain d1ewed_: 1ewe D: [29139] complexed with so4 |
Domain d1ex5a_: 1ex5 A: [29140] |
Domain d1ex5b_: 1ex5 B: [29141] |
Domain d1ex5c_: 1ex5 C: [29142] |
Domain d1ex5d_: 1ex5 D: [29143] |
Domain d1j4ea_: 1j4e A: [66375] complexed with 13p |
Domain d1j4eb_: 1j4e B: [66376] complexed with 13p |
Domain d1j4ec_: 1j4e C: [66377] complexed with 13p |
Domain d1j4ed_: 1j4e D: [66378] complexed with 13p |
Domain d1zaha1: 1zah A:1-363 [124824] |
Domain d1zahb_: 1zah B: [124825] automated match to d1adoa_ |
Domain d1zahc_: 1zah C: [124826] automated match to d1adoa_ |
Domain d1zahd_: 1zah D: [124827] automated match to d1adoa_ |
Domain d1zaia_: 1zai A: [124828] automated match to d1adoa_ complexed with 2fp |
Domain d1zaib_: 1zai B: [124829] automated match to d1adoa_ complexed with 2fp |
Domain d1zaic_: 1zai C: [124830] automated match to d1adoa_ complexed with 2fp |
Domain d1zaid_: 1zai D: [124831] automated match to d1adoa_ complexed with 2fp |
Domain d1zaja_: 1zaj A: [124832] automated match to d1adoa_ complexed with m2p |
Domain d1zajb_: 1zaj B: [124833] automated match to d1adoa_ complexed with m2p |
Domain d1zajc_: 1zaj C: [124834] automated match to d1adoa_ complexed with m2p |
Domain d1zajd_: 1zaj D: [124835] automated match to d1adoa_ complexed with m2p |
Domain d1zala_: 1zal A: [124836] automated match to d1adoa_ complexed with po4 |
Domain d1zalb_: 1zal B: [124837] automated match to d1adoa_ complexed with po4 |
Domain d1zalc_: 1zal C: [124838] automated match to d1adoa_ complexed with po4 |
Domain d1zald_: 1zal D: [124839] automated match to d1adoa_ complexed with po4 |
Domain d2ot0a_: 2ot0 A: [139303] automated match to d1adoa_ |
Domain d2ot0b_: 2ot0 B: [139304] automated match to d1adoa_ |
Domain d2ot0c_: 2ot0 C: [139305] automated match to d1adoa_ |
Domain d2ot0d_: 2ot0 D: [139306] automated match to d1adoa_ |
Domain d2ot1a_: 2ot1 A: [139307] automated match to d1adoa_ complexed with n3p |
Domain d2ot1b_: 2ot1 B: [139308] automated match to d1adoa_ complexed with n3p |
Domain d2ot1c_: 2ot1 C: [139309] automated match to d1adoa_ complexed with n3p |
Domain d2ot1d_: 2ot1 D: [139310] automated match to d1adoa_ complexed with n3p |
Domain d2quta_: 2qut A: [151376] automated match to d1adoa_ complexed with 13p |
Domain d2qutb_: 2qut B: [151377] automated match to d1adoa_ complexed with 13p |
Domain d2qutc_: 2qut C: [151378] automated match to d1adoa_ complexed with 13p |
Domain d2qutd_: 2qut D: [151379] automated match to d1adoa_ complexed with 13p |
Domain d2quua_: 2quu A: [167814] automated match to d1adoa_ complexed with 13p; mutant |
Domain d2quub_: 2quu B: [167815] automated match to d1adoa_ complexed with 13p; mutant |
Domain d2quuc_: 2quu C: [167816] automated match to d1adoa_ complexed with 13p; mutant |
Domain d2quud_: 2quu D: [167817] automated match to d1adoa_ complexed with 13p; mutant |
Domain d2quva_: 2quv A: [151380] automated match to d1adoa_ complexed with po4 |
Domain d2quvb_: 2quv B: [151381] automated match to d1adoa_ complexed with po4 |
Domain d2quvc_: 2quv C: [151382] automated match to d1adoa_ complexed with po4 |
Domain d2quvd_: 2quv D: [151383] automated match to d1adoa_ complexed with po4 |
Domain d3b8da_: 3b8d A: [154951] automated match to d1adoa_ complexed with so4 |
Domain d3b8db_: 3b8d B: [154952] automated match to d1adoa_ complexed with so4 |
Domain d3b8dc_: 3b8d C: [154953] automated match to d1adoa_ complexed with so4 |
Domain d3b8dd_: 3b8d D: [154954] automated match to d1adoa_ complexed with so4 |
Domain d3bv4a1: 3bv4 A:4-343 [208721] Other proteins in same PDB: d3bv4a2 automated match to d1j4ea_ complexed with 13p, so4 |
Domain d3dfna_: 3dfn A: [173892] automated match to d1adoa_ mutant |
Domain d3dfnb_: 3dfn B: [173893] automated match to d1adoa_ mutant |
Domain d3dfnc_: 3dfn C: [173894] automated match to d1adoa_ mutant |
Domain d3dfnd_: 3dfn D: [173895] automated match to d1adoa_ mutant |
Domain d3dfoa_: 3dfo A: [173896] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfob_: 3dfo B: [173897] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfoc_: 3dfo C: [173898] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfod_: 3dfo D: [173899] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfpa_: 3dfp A: [173900] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dfpb_: 3dfp B: [173901] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dfpc_: 3dfp C: [173902] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dfpd_: 3dfp D: [173903] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dfqa_: 3dfq A: [173904] automated match to d1adoa_ mutant |
Domain d3dfqb_: 3dfq B: [173905] automated match to d1adoa_ mutant |
Domain d3dfqc_: 3dfq C: [173906] automated match to d1adoa_ mutant |
Domain d3dfqd_: 3dfq D: [173907] automated match to d1adoa_ mutant |
Domain d3dfsa_: 3dfs A: [173908] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfsb_: 3dfs B: [173909] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfsc_: 3dfs C: [173910] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfsd_: 3dfs D: [173911] automated match to d1adoa_ complexed with 13p; mutant |
Domain d3dfta_: 3dft A: [173912] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dftb_: 3dft B: [173913] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dftc_: 3dft C: [173914] automated match to d1adoa_ complexed with po4; mutant |
Domain d3dftd_: 3dft D: [173915] automated match to d1adoa_ complexed with po4; mutant |
Domain d3lgea_: 3lge A: [180274] automated match to d1adoa_ |
Domain d3lgeb_: 3lge B: [180275] automated match to d1adoa_ |
Domain d3lgec_: 3lge C: [180276] automated match to d1adoa_ |
Domain d3lged_: 3lge D: [180277] automated match to d1adoa_ |
Domain d3tu9a_: 3tu9 A: [185952] automated match to d1adoa_ complexed with 5mm |
Domain d3tu9b_: 3tu9 B: [185953] automated match to d1adoa_ complexed with 5mm |
Domain d3tu9c_: 3tu9 C: [185954] automated match to d1adoa_ complexed with 5mm |
Domain d3tu9d_: 3tu9 D: [185955] automated match to d1adoa_ complexed with 5mm |
Domain d5f4xa_: 5f4x A: [327631] automated match to d1ewea_ complexed with gol; mutant |
Domain d5f4xb_: 5f4x B: [327552] automated match to d1ewea_ complexed with gol; mutant |
Domain d5f4xc_: 5f4x C: [327553] automated match to d1ewea_ complexed with gol; mutant |
Domain d5f4xd_: 5f4x D: [327615] automated match to d1ewea_ complexed with gol; mutant |
Domain d5tlea_: 5tle A: [340613] automated match to d1zaha1 complexed with gol, rd1 |
Domain d5tleb_: 5tle B: [340651] automated match to d1zaha1 complexed with gol, rd1 |
Domain d5tlec_: 5tle C: [340616] automated match to d1zaha1 complexed with gol, rd1 |
Domain d5tled_: 5tle D: [340614] automated match to d1zaha1 complexed with gol, rd1 |
Domain d5tlha_: 5tlh A: [340659] automated match to d1zaha1 complexed with gol, mdn, rd2 |
Domain d5tlhb_: 5tlh B: [340800] automated match to d1zaha1 complexed with gol, mdn, rd2 |
Domain d5tlhc_: 5tlh C: [340728] automated match to d1zaha1 complexed with gol, mdn, rd2 |
Domain d5tlhd_: 5tlh D: [340776] automated match to d1zaha1 complexed with gol, mdn, rd2 |
Domain d5tlwa_: 5tlw A: [340637] automated match to d1zaha1 complexed with gol, rd3 |
Domain d5tlwb_: 5tlw B: [340734] automated match to d1zaha1 complexed with gol, rd3 |
Domain d5tlwc_: 5tlw C: [340793] automated match to d1zaha1 complexed with gol, rd3 |
Domain d5tlwd_: 5tlw D: [340646] automated match to d1zaha1 complexed with gol, rd3 |
Domain d5tlza_: 5tlz A: [340609] automated match to d1zaha1 complexed with gol, n26 |
Domain d5tlzb_: 5tlz B: [340610] automated match to d1zaha1 complexed with gol, n26 |
Domain d5tlzc_: 5tlz C: [340608] automated match to d1zaha1 complexed with gol, n26 |
Domain d5tlzd_: 5tlz D: [340677] automated match to d1zaha1 complexed with gol, n26 |
Domain d5vy5a_: 5vy5 A: [335478] automated match to d1zaha1 |
Domain d5vy5b_: 5vy5 B: [335496] automated match to d1zaha1 |
Domain d5vy5c_: 5vy5 C: [335538] automated match to d1zaha1 |
Domain d5vy5d_: 5vy5 D: [335473] automated match to d1zaha1 |
Domain d6alda_: 6ald A: [29144] complexed with 2fp |
Domain d6aldb_: 6ald B: [29145] complexed with 2fp |
Domain d6aldc_: 6ald C: [29146] complexed with 2fp |
Domain d6aldd_: 6ald D: [29147] complexed with 2fp |
Domain d6v20a_: 6v20 A: [380611] automated match to d5vy5a_ |
Domain d6v20b_: 6v20 B: [380564] automated match to d5vy5a_ |
Domain d6v20c_: 6v20 C: [380566] automated match to d5vy5a_ |
Domain d6v20d_: 6v20 D: [380613] automated match to d5vy5a_ |
Domain d7ka4a_: 7ka4 A: [394830] automated match to d1zaha1 |
Domain d7ka4b_: 7ka4 B: [394840] automated match to d1zaha1 |
Domain d7ka4c_: 7ka4 C: [394858] automated match to d1zaha1 |
Domain d7ka4d_: 7ka4 D: [394799] automated match to d1zaha1 |
Domain d1epxa_: 1epx A: [29150] |
Domain d1epxb_: 1epx B: [29151] |
Domain d1epxc_: 1epx C: [29152] |
Domain d1epxd_: 1epx D: [29153] |
Trypanosome (Trypanosoma brucei) [TaxId:5691] [51583] (1 PDB entry) |
Domain d1f2ja_: 1f2j A: [29154] |
Timeline for Protein Fructose-1,6-bisphosphate aldolase from c.1.10.1: Class I aldolase: