Lineage for Protein: Dihydrodipicolinate synthase

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2420459Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2420460Family c.1.10.1: Class I aldolase [51570] (13 protein domains)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. 2420591Protein Dihydrodipicolinate synthase [51574] (13 species)

Species:

  1. 2420592Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [141832] (2 PDB entries)
    Uniprot Q81WN7 1-292
    1. Domains for 1xky:
      1. 2420593Domain d1xkya1: 1xky A:1-292 [122094]
        complexed with k
      2. 2420594Domain d1xkyb_: 1xky B: [122095]
        automated match to d1xkya1
        complexed with k
      3. 2420595Domain d1xkyc_: 1xky C: [122096]
        automated match to d1xkya1
        complexed with k
      4. 2420596Domain d1xkyd_: 1xky D: [122097]
        automated match to d1xkya1
        complexed with k
    2. Domains for 1xl9:
      1. 2420597Domain d1xl9a_: 1xl9 A: [122108]
        automated match to d1xkya1
      2. 2420598Domain d1xl9b_: 1xl9 B: [122109]
        automated match to d1xkya1
      3. 2420599Domain d1xl9c_: 1xl9 C: [122110]
        automated match to d1xkya1
      4. 2420600Domain d1xl9d_: 1xl9 D: [122111]
        automated match to d1xkya1
  2. 2420601Campylobacter jejuni [TaxId:192222] [189204] (3 PDB entries)
    1. Domains for 3ler:
      1. 2420602Domain d3lera_: 3ler A: [180235]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg
      2. 2420603Domain d3lerb_: 3ler B: [180236]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg
      3. 2420604Domain d3lerc_: 3ler C: [180237]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg
      4. 2420605Domain d3lerd_: 3ler D: [180238]
        automated match to d1o5ka_
        complexed with acy, edo, fmt, mg, peg
    2. Domains for 5f1u:
      1. 2420610Domain d5f1ua_: 5f1u A: [313912]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge
      2. 2420611Domain d5f1ub_: 5f1u B: [313876]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge
      3. 2420612Domain d5f1uc_: 5f1u C: [313891]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge
      4. 2420613Domain d5f1ud_: 5f1u D: [313935]
        automated match to d3lera_
        complexed with 3vn, cl, edo, pg4, pge
    3. Domains for 5f1v:
      1. 2420606Domain d5f1va_: 5f1v A: [313873]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge
      2. 2420607Domain d5f1vb_: 5f1v B: [313996]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge
      3. 2420608Domain d5f1vc_: 5f1v C: [314125]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge
      4. 2420609Domain d5f1vd_: 5f1v D: [314016]
        automated match to d3lera_
        complexed with 3vn, edo, gol, pge
  3. 2420614Clostridium botulinum [TaxId:441770] [189380] (1 PDB entry)
  4. 2420617Clostridium botulinum [TaxId:441771] [189048] (2 PDB entries)
    1. Domain for 3bi8:
    2. Domain for 3ird:
  5. 2420620Corynebacterium glutamicum [TaxId:1718] [188663] (1 PDB entry)
  6. 2420623Escherichia coli K-12 [TaxId:83333] [188673] (3 PDB entries)
    1. Domains for 3den:
      1. 2420626Domain d3dena_: 3den A: [173872]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
      2. 2420627Domain d3denb_: 3den B: [173873]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
    2. Domains for 3i7r:
      1. 2420624Domain d3i7ra_: 3i7r A: [178135]
        automated match to d1dhpa_
        complexed with cl, gol, k, po4
      2. 2420625Domain d3i7rb_: 3i7r B: [178136]
        automated match to d1dhpa_
        complexed with cl, gol, k, po4
    3. Domains for 3i7s:
      1. 2420628Domain d3i7sa_: 3i7s A: [178137]
        automated match to d1dhpa_
        complexed with gol, k, po4, pyr; mutant
      2. 2420629Domain d3i7sb_: 3i7s B: [178138]
        automated match to d1dhpa_
        complexed with gol, k, po4, pyr; mutant
  7. 2420630Escherichia coli [TaxId:562] [51575] (16 PDB entries)
    1. Domains for 1dhp:
      1. 2420651Domain d1dhpa_: 1dhp A: [29097]
        complexed with k
      2. 2420652Domain d1dhpb_: 1dhp B: [29098]
        complexed with k
    2. Domains for 1s5t:
      1. 2420645Domain d1s5ta_: 1s5t A: [98571]
        mutant
      2. 2420646Domain d1s5tb_: 1s5t B: [98572]
        mutant
    3. Domains for 1s5v:
      1. 2420649Domain d1s5va_: 1s5v A: [98581]
        mutant
      2. 2420650Domain d1s5vb_: 1s5v B: [98582]
        mutant
    4. Domains for 1s5w:
      1. 2420647Domain d1s5wa_: 1s5w A: [98583]
        mutant
      2. 2420648Domain d1s5wb_: 1s5w B: [98584]
        mutant
    5. Domains for 1yxc:
      1. 2420655Domain d1yxca_: 1yxc A: [124183]
        automated match to d1dhpa_
        complexed with cl, k
      2. 2420656Domain d1yxcb_: 1yxc B: [124184]
        automated match to d1dhpa_
        complexed with cl, k
    6. Domains for 1yxd:
      1. 2420659Domain d1yxda_: 1yxd A: [124185]
        automated match to d1dhpa_
        complexed with cl, k, lys
      2. 2420660Domain d1yxdb_: 1yxd B: [124186]
        automated match to d1dhpa_
        complexed with cl, k, lys
    7. Domains for 2a6l:
      1. 2420661Domain d2a6la1: 2a6l A:1-292 [126285]
        complexed with k; mutant
      2. 2420662Domain d2a6lb_: 2a6l B: [126286]
        automated match to d1dhpa_
        complexed with k; mutant
    8. Domains for 2a6n:
      1. 2420657Domain d2a6na1: 2a6n A:1-292 [126289]
        complexed with k; mutant
      2. 2420658Domain d2a6nb_: 2a6n B: [126290]
        automated match to d1dhpa_
        complexed with k; mutant
    9. Domains for 2ats:
      1. 2420653Domain d2atsa_: 2ats A: [127306]
        automated match to d1dhpa_
        complexed with cl, dly, k
      2. 2420654Domain d2atsb_: 2ats B: [127307]
        automated match to d1dhpa_
        complexed with cl, dly, k
    10. Domains for 2ojp:
      1. 2420641Domain d2ojpa_: 2ojp A: [166718]
        automated match to d1dhpa_
        complexed with gol; mutant
      2. 2420642Domain d2ojpb_: 2ojp B: [166719]
        automated match to d1dhpa_
        complexed with gol; mutant
    11. Domains for 2pur:
      1. 2420631Domain d2pura_: 2pur A: [167275]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
      2. 2420632Domain d2purb_: 2pur B: [167276]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
    12. Domains for 3c0j:
      1. 2420643Domain d3c0ja_: 3c0j A: [172973]
        automated match to d1dhpa_
        complexed with gol, k, po4
      2. 2420644Domain d3c0jb_: 3c0j B: [172974]
        automated match to d1dhpa_
        complexed with gol, k, po4
    13. Domains for 3du0:
      1. 2420633Domain d3du0a_: 3du0 A: [174226]
        automated match to d1dhpa_
        complexed with cl, gol, k
      2. 2420634Domain d3du0b_: 3du0 B: [174227]
        automated match to d1dhpa_
        complexed with cl, gol, k
    14. Domains for 3i7q:
      1. 2420635Domain d3i7qa_: 3i7q A: [178133]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
      2. 2420636Domain d3i7qb_: 3i7q B: [178134]
        automated match to d1dhpa_
        complexed with gol, k, po4; mutant
    15. Domains for 3ubs:
      1. 2420639Domain d3ubsa_: 3ubs A: [306648]
        automated match to d4eoua_
        complexed with gol, k
      2. 2420640Domain d3ubsb_: 3ubs B: [306649]
        automated match to d4eoua_
        complexed with gol, k
    16. Domains for 4eou:
      1. 2420637Domain d4eoua_: 4eou A: [192395]
        complexed with gol, k
      2. 2420638Domain d4eoub_: 4eou B: [192396]
        complexed with gol, k
  8. 2420663Escherichia coli [TaxId:585034] [323806] (2 PDB entries)
    1. Domains for 5t25:
      1. 2420664Domain d5t25a1: 5t25 A:1-292 [330476]
        Other proteins in same PDB: d5t25a2
        automated match to d3du0a_
        complexed with lys, na
      2. 2420665Domain d5t25b_: 5t25 B: [330478]
        Other proteins in same PDB: d5t25a2
        automated match to d3du0a_
        complexed with lys, na
    2. Domains for 5t26:
      1. 2420666Domain d5t26a1: 5t26 A:1-292 [323869]
        Other proteins in same PDB: d5t26a2, d5t26b2
        automated match to d2atsa_
        complexed with gol, na, tla
      2. 2420667Domain d5t26b1: 5t26 B:1-292 [323807]
        Other proteins in same PDB: d5t26a2, d5t26b2
        automated match to d2atsa_
        complexed with gol, na, tla
  9. 2420668Methanocaldococcus jannaschii [TaxId:243232] [188258] (1 PDB entry)
  10. 2420673Mycobacterium tuberculosis [TaxId:1773] [141831] (2 PDB entries)
    Uniprot P63945 5-300
    1. Domains for 1xxx:
      1. 2420674Domain d1xxxa1: 1xxx A:5-300 [122433]
        complexed with cl, dtt, mg
      2. 2420675Domain d1xxxb_: 1xxx B: [122434]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      3. 2420676Domain d1xxxc_: 1xxx C: [122435]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      4. 2420677Domain d1xxxd_: 1xxx D: [122436]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      5. 2420678Domain d1xxxe_: 1xxx E: [122437]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      6. 2420679Domain d1xxxf_: 1xxx F: [122438]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      7. 2420680Domain d1xxxg_: 1xxx G: [122439]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
      8. 2420681Domain d1xxxh_: 1xxx H: [122440]
        automated match to d1o5ka_
        complexed with cl, dtt, mg
    2. Domain for 5j5d:
  11. 2420683Pseudomonas aeruginosa [TaxId:287] [189992] (1 PDB entry)
  12. 2420686Pseudomonas aeruginosa, PA01 [TaxId:208964] [189575] (2 PDB entries)
    1. Domains for 3ps7:
      1. 2420689Domain d3ps7a_: 3ps7 A: [183949]
        automated match to d1dhpa_
        complexed with pgo
      2. 2420690Domain d3ps7b_: 3ps7 B: [183950]
        automated match to d1dhpa_
        complexed with pgo
    2. Domains for 3puo:
      1. 2420687Domain d3puoa_: 3puo A: [183980]
        automated match to d1dhpa_
        complexed with gol, lys
      2. 2420688Domain d3puob_: 3puo B: [183981]
        automated match to d1dhpa_
        complexed with gol, lys
  13. 2420691Thermotoga maritima [TaxId:2336] [102090] (1 PDB entry)

More info for Protein Dihydrodipicolinate synthase from c.1.10.1: Class I aldolase

Timeline for Protein Dihydrodipicolinate synthase from c.1.10.1: Class I aldolase: