SCOPe 2.02: Protein: N-acetylneuraminate lyase

Lineage for Protein: N-acetylneuraminate lyase

Root: SCOPe 2.02
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.10: Aldolase [51569] (9 families)
Common fold covers whole protein structure

Family c.1.10.1: Class I aldolase [51570] (13 proteins)
the catalytic lysine forms schiff-base intermediate with substrate
possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

Protein N-acetylneuraminate lyase [51571] (2 species)

Species:

Escherichia coli [TaxId:562] [51572] (4 PDB entries)
1. Domains for 1fdy:
  1. Domain d1fdya_: 1fdy A: [29071]
    complexed with 3py
  2. Domain d1fdyb_: 1fdy B: [29072]
    complexed with 3py
  3. Domain d1fdyc_: 1fdy C: [29073]
    complexed with 3py
  4. Domain d1fdyd_: 1fdy D: [29074]
    complexed with 3py
2. Domains for 1fdz:
  1. Domain d1fdza_: 1fdz A: [29075]
    complexed with pyr
  2. Domain d1fdzb_: 1fdz B: [29076]
    complexed with pyr
  3. Domain d1fdzc_: 1fdz C: [29077]
    complexed with pyr
  4. Domain d1fdzd_: 1fdz D: [29078]
    complexed with pyr
3. Domains for 1hl2:
  1. Domain d1hl2a_: 1hl2 A: [83581]
    complexed with 3py; mutant
  2. Domain d1hl2b_: 1hl2 B: [83582]
    complexed with 3py; mutant
  3. Domain d1hl2c_: 1hl2 C: [83583]
    complexed with 3py; mutant
  4. Domain d1hl2d_: 1hl2 D: [83584]
    complexed with 3py; mutant
4. Domains for 1nal:
  1. Domain d1nal1_: 1nal 1: [29067]
    complexed with so4
  2. Domain d1nal2_: 1nal 2: [29068]
    complexed with so4
  3. Domain d1nal3_: 1nal 3: [29069]
    complexed with so4
  4. Domain d1nal4_: 1nal 4: [29070]
    complexed with so4
Haemophilus influenzae [TaxId:727] [51573] (6 PDB entries)
1. Domains for 1f5z:
  1. Domain d1f5za_: 1f5z A: [29085]
  2. Domain d1f5zb_: 1f5z B: [29086]
  3. Domain d1f5zc_: 1f5z C: [29087]
  4. Domain d1f5zd_: 1f5z D: [29088]
2. Domains for 1f6k:
  1. Domain d1f6ka_: 1f6k A: [29081]
    complexed with gol, so4
  2. Domain d1f6kc_: 1f6k C: [29082]
    complexed with gol, so4
3. Domains for 1f6p:
  1. Domain d1f6pa_: 1f6p A: [29093]
  2. Domain d1f6pb_: 1f6p B: [29094]
  3. Domain d1f6pc_: 1f6p C: [29095]
  4. Domain d1f6pd_: 1f6p D: [29096]
4. Domains for 1f73:
  1. Domain d1f73a_: 1f73 A: [29089]
    complexed with gol, hmn
  2. Domain d1f73b_: 1f73 B: [29090]
    complexed with gol, hmn
  3. Domain d1f73c_: 1f73 C: [29091]
    complexed with gol, hmn
  4. Domain d1f73d_: 1f73 D: [29092]
    complexed with gol, hmn
5. Domains for 1f74:
  1. Domain d1f74a_: 1f74 A: [29079]
    complexed with cl, gol, nay
  2. Domain d1f74c_: 1f74 C: [29080]
    complexed with cl, gol, nay
6. Domains for 1f7b:
  1. Domain d1f7ba_: 1f7b A: [29083]
    complexed with cl, nau, nav
  2. Domain d1f7bc_: 1f7b C: [29084]
    complexed with cl, nau, nav

More info for Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase

Timeline for Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase:

Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase first appeared (with stable ids) in SCOP 1.55
Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase appears in SCOPe 2.01
Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase appears in SCOPe 2.03
Protein N-acetylneuraminate lyase from c.1.10.1: Class I aldolase appears in the current release, SCOPe 2.08