Lineage for Superfamily c.1.10: Aldolase

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1815292Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 1821671Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure

Families:

  1. 1821672c.1.10.1: Class I aldolase [51570] (13 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  2. 1822456c.1.10.2: Class II FBP aldolase [51591] (3 proteins)
    metal-dependent
    automatically mapped to Pfam PF01116
  3. 1822493c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins)
    hybrid of classes I and II aldolase
    automatically mapped to Pfam PF00490
  4. 1822562c.1.10.4: Class I DAHP synthetase [51599] (3 proteins)
  5. 1822872c.1.10.5: HMGL-like [89494] (3 proteins)
    Pfam PF00682
  6. 1822891c.1.10.6: NeuB-like [110368] (3 proteins)
    Pfam PF03102
  7. 1822907c.1.10.7: GatZ-like [141837] (1 protein)
    Pfam PF08013
  8. 1822914c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins)
    Pfam PF01474
  9. 1822946c.1.10.0: automated matches [191319] (1 protein)
    not a true family

More info for Superfamily c.1.10: Aldolase

Timeline for Superfamily c.1.10: Aldolase: