Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.10: Aldolase [51569] (9 families) Common fold covers whole protein structure |
c.1.10.1: Class I aldolase [51570] (13 proteins) the catalytic lysine forms schiff-base intermediate with substrate possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels |
c.1.10.2: Class II FBP aldolase [51591] (3 proteins) metal-dependent automatically mapped to Pfam PF01116 |
c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins) hybrid of classes I and II aldolase automatically mapped to Pfam PF00490 |
c.1.10.4: Class I DAHP synthetase [51599] (3 proteins) |
c.1.10.5: HMGL-like [89494] (3 proteins) Pfam PF00682 |
c.1.10.6: NeuB-like [110368] (3 proteins) Pfam PF03102 |
c.1.10.7: GatZ-like [141837] (1 protein) Pfam PF08013 |
c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins) Pfam PF01474 |
c.1.10.0: automated matches [191319] (1 protein) not a true family |
Timeline for Superfamily c.1.10: Aldolase: