Lineage for Protein: Adenosine deaminase (ADA)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2084338Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families) (S)
    the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
    has transition metal ions bound inside the barrel
  5. 2084339Family c.1.9.1: Adenosine/AMP deaminase [51557] (3 protein domains)
  6. 2084340Protein Adenosine deaminase (ADA) [51558] (4 species)
    Common fold covers the whole protein structure

Species:

  1. 2084341Cow (Bos taurus) [TaxId:9913] [82257] (13 PDB entries)
    Uniprot P56658 3-350 ! Uniprot P56658
    1. Domain for 1krm:
    2. Domain for 1ndv:
    3. Domain for 1ndw:
    4. Domain for 1ndy:
    5. Domain for 1ndz:
    6. Domain for 1o5r:
    7. Domain for 1qxl:
    8. Domain for 1uml:
    9. Domain for 1v78:
    10. Domain for 1v79:
    11. Domain for 1v7a:
    12. Domains for 1w1i:
      1. 2084353Domain d1w1ie_: 1w1i E: [109051]
        Other proteins in same PDB: d1w1ia1, d1w1ia2, d1w1ib1, d1w1ib2, d1w1ic1, d1w1ic2, d1w1id1, d1w1id2
        complexed with nag, ndg, zn
      2. 2084354Domain d1w1if_: 1w1i F: [109052]
        Other proteins in same PDB: d1w1ia1, d1w1ia2, d1w1ib1, d1w1ib2, d1w1ic1, d1w1ic2, d1w1id1, d1w1id2
        complexed with nag, ndg, zn
      3. 2084355Domain d1w1ig_: 1w1i G: [109053]
        Other proteins in same PDB: d1w1ia1, d1w1ia2, d1w1ib1, d1w1ib2, d1w1ic1, d1w1ic2, d1w1id1, d1w1id2
        complexed with nag, ndg, zn
      4. 2084356Domain d1w1ih_: 1w1i H: [109054]
        Other proteins in same PDB: d1w1ia1, d1w1ia2, d1w1ib1, d1w1ib2, d1w1ic1, d1w1ic2, d1w1id1, d1w1id2
        complexed with nag, ndg, zn
    13. Domains for 2bgn:
      1. 2084357Domain d2bgne1: 2bgn E:4-355 [128492]
        Other proteins in same PDB: d2bgna1, d2bgna2, d2bgnb1, d2bgnb2, d2bgnc1, d2bgnc2, d2bgnd1, d2bgnd2
        automatically matched to d1w1ie_
        complexed with nag, zn
      2. 2084358Domain d2bgnf1: 2bgn F:4-355 [128493]
        Other proteins in same PDB: d2bgna1, d2bgna2, d2bgnb1, d2bgnb2, d2bgnc1, d2bgnc2, d2bgnd1, d2bgnd2
        automatically matched to d1w1ie_
        complexed with nag, zn
      3. 2084359Domain d2bgng1: 2bgn G:4-355 [128494]
        Other proteins in same PDB: d2bgna1, d2bgna2, d2bgnb1, d2bgnb2, d2bgnc1, d2bgnc2, d2bgnd1, d2bgnd2
        automatically matched to d1w1ie_
        complexed with nag, zn
      4. 2084360Domain d2bgnh1: 2bgn H:4-355 [128495]
        Other proteins in same PDB: d2bgna1, d2bgna2, d2bgnb1, d2bgnb2, d2bgnc1, d2bgnc2, d2bgnd1, d2bgnd2
        automatically matched to d1w1ie_
        complexed with nag, zn
  2. 2084361Human (Homo sapiens) [TaxId:9606] [224876] (1 PDB entry)
  3. 2084363Mouse (Mus musculus) [TaxId:10090] [51559] (10 PDB entries)
    1. Domains for 1a4l:
      1. 2084377Domain d1a4la_: 1a4l A: [29023]
        complexed with dcf, zn
      2. 2084378Domain d1a4lb_: 1a4l B: [29024]
        complexed with dcf, zn
      3. 2084379Domain d1a4lc_: 1a4l C: [29025]
        complexed with dcf, zn
      4. 2084380Domain d1a4ld_: 1a4l D: [29026]
        complexed with dcf, zn
    2. Domains for 1a4m:
      1. 2084366Domain d1a4ma_: 1a4m A: [29014]
        complexed with prh, zn
      2. 2084367Domain d1a4mb_: 1a4m B: [29015]
        complexed with prh, zn
      3. 2084368Domain d1a4mc_: 1a4m C: [29016]
        complexed with prh, zn
      4. 2084369Domain d1a4md_: 1a4m D: [29017]
        complexed with prh, zn
    3. Domain for 1add:
    4. Domain for 1fkw:
    5. Domain for 1fkx:
    6. Domain for 1uio:
    7. Domain for 1uip:
    8. Domain for 2ada:
    9. Domains for 3mvi:
      1. 2084364Domain d3mvia_: 3mvi A: [213590]
        automated match to d1a4ma_
        complexed with gol, zn
      2. 2084365Domain d3mvib_: 3mvi B: [213591]
        automated match to d1a4ma_
        complexed with gol, zn
    10. Domains for 3mvt:
      1. 2084370Domain d3mvta_: 3mvt A: [213609]
        automated match to d1a4ma_
        complexed with cl, gol
      2. 2084371Domain d3mvtc_: 3mvt C: [213610]
        automated match to d1a4ma_
        complexed with cl, gol
  4. 2084382Plasmodium yoelii [TaxId:5861] [141799] (1 PDB entry)
    Uniprot Q7RMV2 8-364

More info for Protein Adenosine deaminase (ADA) from c.1.9.1: Adenosine/AMP deaminase

Timeline for Protein Adenosine deaminase (ADA) from c.1.9.1: Adenosine/AMP deaminase: