SCOP 1.73: Family c.1.9.1: Adenosine/AMP deaminase

Lineage for Family c.1.9.1: Adenosine/AMP deaminase

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (15 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.1: Adenosine/AMP deaminase [51557] (2 proteins)

Proteins:

1. Adenosine deaminase (ADA) [51558] (3 species)
   Common fold covers the whole protein structure

   1. Species Cow (Bos taurus) [TaxId:9913] [82257] (16 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [51559] (8 PDB entries)

   3. Species Plasmodium yoelii [TaxId:5861] [141799] (1 PDB entry)

2. AMP deaminase (AMPD), catalytic domain [141800] (1 species)
   elaborated fold with additional structures

   • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [141801] (1 PDB entry)

More info for Family c.1.9.1: Adenosine/AMP deaminase

Timeline for Family c.1.9.1: Adenosine/AMP deaminase:

• Family c.1.9.1: Adenosine/AMP deaminase first appeared (with stable ids) in SCOP 1.55, called Family c.1.9.1: Adenosine deaminase (ADA)
  
• Family c.1.9.1: Adenosine/AMP deaminase was called Family c.1.9.1: Adenosine deaminase (ADA) in SCOP 1.71
  
• Family c.1.9.1: Adenosine/AMP deaminase appears in SCOP 1.75
  
• Family c.1.9.1: Adenosine/AMP deaminase appears in the current release, SCOPe 2.08