Lineage for Family c.1.9.1: Adenosine/AMP deaminase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2833366Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families) (S)
    the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
    has transition metal ions bound inside the barrel
  5. 2833367Family c.1.9.1: Adenosine/AMP deaminase [51557] (3 proteins)

Proteins:

  1. 2833368Adenosine deaminase (ADA) [51558] (4 species)
    Common fold covers the whole protein structure
    1. 2833369Species Cow (Bos taurus) [TaxId:9913] [82257] (13 PDB entries)
      Uniprot P56658 3-350 ! Uniprot P56658
    2. 2833389Species Human (Homo sapiens) [TaxId:9606] [224876] (1 PDB entry)
    3. 2833391Species Mouse (Mus musculus) [TaxId:10090] [51559] (10 PDB entries)
    4. 2833410Species Plasmodium yoelii [TaxId:5861] [141799] (1 PDB entry)
      Uniprot Q7RMV2 8-364
  2. 2833412AMP deaminase (AMPD), catalytic domain [141800] (1 species)
    elaborated fold with additional structures
  3. 2833415automated matches [190078] (5 species)
    not a true protein
    1. 2833416Species Cow (Bos taurus) [TaxId:9913] [186799] (5 PDB entries)
    2. 2833422Species Plasmodium falciparum [TaxId:36329] [368411] (1 PDB entry)
    3. 2833424Species Plasmodium vivax [TaxId:126793] [188010] (1 PDB entry)
    4. 2833426Species Plasmodium vivax [TaxId:5855] [187988] (4 PDB entries)
    5. 2833431Species Plasmodium yoelii [TaxId:5861] [187410] (1 PDB entry)

More info for Family c.1.9.1: Adenosine/AMP deaminase

Timeline for Family c.1.9.1: Adenosine/AMP deaminase: