SCOPe 2.02: Superfamily c.1.9: Metallo-dependent hydrolases

Lineage for Superfamily c.1.9: Metallo-dependent hydrolases

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

Families:

1. c.1.9.1: Adenosine/AMP deaminase [51557] (3 proteins)

2. c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)

3. c.1.9.3: Phosphotriesterase-like [51564] (3 proteins)

4. c.1.9.4: Dihydroorotase [63917] (2 proteins)

5. c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein)

6. c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)

7. c.1.9.7: Renal dipeptidase [75079] (1 protein)

8. c.1.9.8: Uronate isomerase-like [75082] (2 proteins)
   contains all-alpha subdomain inserted after the first strand

9. c.1.9.9: SAH/MTA deaminase-like [82258] (3 proteins)

10. c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain [82261] (1 protein)

11. c.1.9.11: D-aminoacylase, catalytic domain [82264] (1 protein)

12. c.1.9.12: TatD Mg-dependent DNase-like [82267] (4 proteins)

13. c.1.9.13: Isoaspartyl dipeptidase, catalytic domain [89489] (1 protein)

14. c.1.9.14: Adenine deaminase-like [141816] (1 protein)

15. c.1.9.15: PP1699/LP2961-like [141819] (5 proteins)
    Pfam PF04909; Amidohydrolase; stand-alone domain

16. c.1.9.16: DR0824-like [159397] (1 protein)

17. c.1.9.17: Imidazolonepropionase-like [159400] (3 proteins)

18. c.1.9.18: Zn-dependent arginine carboxypeptidase-like [159408] (3 proteins)

19. c.1.9.0: automated matches [191327] (1 protein)
    not a true family

More info for Superfamily c.1.9: Metallo-dependent hydrolases

Timeline for Superfamily c.1.9: Metallo-dependent hydrolases:

• Superfamily c.1.9: Metallo-dependent hydrolases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily c.1.9: Metallo-dependent hydrolases appears in SCOPe 2.01
  
• Superfamily c.1.9: Metallo-dependent hydrolases appears in SCOPe 2.03
  
• Superfamily c.1.9: Metallo-dependent hydrolases appears in the current release, SCOPe 2.08