Lineage for Superfamily c.1.9: Metallo-dependent hydrolases

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 305036Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 306527Superfamily c.1.9: Metallo-dependent hydrolases [51556] (13 families) (S)
    the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
    has transition metal ions bound inside the barrel

Families:

  1. 306528c.1.9.1: Adenosine deaminase (ADA) [51557] (1 protein)
  2. 306547c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)
  3. 306585c.1.9.3: Phosphotriesterase-like [51564] (2 proteins)
  4. 306608c.1.9.4: Dihydroorotase [63917] (1 protein)
  5. 306613c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein)
  6. 306618c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (2 proteins)
  7. 306651c.1.9.7: Renal dipeptidase [75079] (1 protein)
  8. 306658c.1.9.8: Uronate isomerase TM0064 [75082] (1 protein)
    contains all-alpha subdomain inserted after the first strand
  9. 306664c.1.9.9: Hypothetical protein TM0936, probable catalytic domain [82258] (1 protein)
  10. 306669c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, catalytic domain [82261] (1 protein)
  11. 306674c.1.9.11: D-aminoacylase, catalitic domain [82264] (1 protein)
  12. 306678c.1.9.12: TatD Mg-dependent DNase-like [82267] (1 protein)
  13. 306682c.1.9.13: Isoaspartyl dipeptidase, catalytic domain [89489] (1 protein)

More info for Superfamily c.1.9: Metallo-dependent hydrolases

Timeline for Superfamily c.1.9: Metallo-dependent hydrolases: