Lineage for Superfamily c.1.9: Metallo-dependent hydrolases

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 235645Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 236978Superfamily c.1.9: Metallo-dependent hydrolases [51556] (12 families) (S)
    the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
    has transition metal ions bound inside the barrel

Families:

  1. 236979c.1.9.1: Adenosine deaminase (ADA) [51557] (1 protein)
  2. 236998c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)
  3. 237035c.1.9.3: Phosphotriesterase-like [51564] (2 proteins)
  4. 237058c.1.9.4: Dihydroorotase [63917] (1 protein)
  5. 237063c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein)
  6. 237068c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (2 proteins)
  7. 237096c.1.9.7: Renal dipeptidase [75079] (1 protein)
  8. 237103c.1.9.8: Uronate isomerase TM0064 [75082] (1 protein)
    contains all-alpha subdomain inserted after the first strand
  9. 237109c.1.9.9: Hypothetical protein TM0936, probable catalytic domain [82258] (1 protein)
  10. 237113c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, catalytic domain [82261] (1 protein)
  11. 237118c.1.9.11: D-aminoacylase, catalitic domain [82264] (1 protein)
  12. 237122c.1.9.12: TatD Mg-dependent DNase-like [82267] (1 protein)

More info for Superfamily c.1.9: Metallo-dependent hydrolases

Timeline for Superfamily c.1.9: Metallo-dependent hydrolases: