Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families) the beta-sheet barrel is similarly distorted and capped by a C-terminal helix has transition metal ions bound inside the barrel |
c.1.9.1: Adenosine/AMP deaminase [51557] (3 proteins) |
c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein) |
c.1.9.3: Phosphotriesterase-like [51564] (3 proteins) automatically mapped to Pfam PF02126 |
c.1.9.4: Dihydroorotase [63917] (2 proteins) |
c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein) automatically mapped to Pfam PF13147 automatically mapped to Pfam PF07969 |
c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins) automatically mapped to Pfam PF13147 |
c.1.9.7: Renal dipeptidase [75079] (1 protein) automatically mapped to Pfam PF01244 |
c.1.9.8: Uronate isomerase-like [75082] (2 proteins) contains all-alpha subdomain inserted after the first strand |
c.1.9.9: SAH/MTA deaminase-like [82258] (3 proteins) automatically mapped to Pfam PF01979 |
c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain [82261] (1 protein) automatically mapped to Pfam PF01979 |
c.1.9.11: D-aminoacylase, catalytic domain [82264] (1 protein) |
c.1.9.12: TatD Mg-dependent DNase-like [82267] (5 proteins) automatically mapped to Pfam PF01026 |
c.1.9.13: Isoaspartyl dipeptidase, catalytic domain [89489] (1 protein) |
c.1.9.14: Adenine deaminase-like [141816] (1 protein) automatically mapped to Pfam PF01979 automatically mapped to Pfam PF13147 |
c.1.9.15: PP1699/LP2961-like [141819] (6 proteins) Pfam PF04909; Amidohydrolase; stand-alone domain |
c.1.9.16: DR0824-like [159397] (1 protein) automatically mapped to Pfam PF01979 |
c.1.9.17: Imidazolonepropionase-like [159400] (3 proteins) automatically mapped to Pfam PF13147 |
c.1.9.18: Zn-dependent arginine carboxypeptidase-like [159408] (3 proteins) automatically mapped to Pfam PF01979 |
c.1.9.0: automated matches [191327] (1 protein) not a true family |
Timeline for Superfamily c.1.9: Metallo-dependent hydrolases: