SCOPe 2.08: Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain

Lineage for Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain [51550] (6 proteins)
   Glycosyl hydrolase family 20, GH20
   automatically mapped to Pfam PF00728

Proteins:

1. Bacterial chitobiase (beta-N-acetylhexosaminidase) [51551] (1 species)

   • Species Serratia marcescens [TaxId:615] [51552] (4 PDB entries)

2. beta-hexosaminidase A [159387] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159388] (2 PDB entries)
     Uniprot P06865 167-528

3. beta-hexosaminidase B [89486] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [89487] (6 PDB entries)

4. beta-N-acetylhexosaminidase [63915] (1 species)

   • Species Streptomyces plicatus [TaxId:1922] [63916] (8 PDB entries)

5. Dispersin B, DspB [141788] (1 species)
   N-acetyl-beta-hexosaminidase

   • Species Actinobacillus actinomycetemcomitans [TaxId:714] [141789] (1 PDB entry)
     Uniprot Q840G9 16-359

6. automated matches [237553] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [316877] (1 PDB entry)

   2. Species Streptomyces coelicolor [TaxId:1902] [237558] (3 PDB entries)

More info for Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain

Timeline for Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain:

• Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain first appeared (with stable ids) in SCOP 1.55, called Family c.1.8.6: Bacterial chitobiase (beta-N-acetylhexosaminidase), catalytic domain
  
• Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain appears in SCOPe 2.07