SCOP 1.75: Family c.1.8.4: Family 1 of glycosyl hydrolase

Lineage for Family c.1.8.4: Family 1 of glycosyl hydrolase

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (14 families)

5. Family c.1.8.4: Family 1 of glycosyl hydrolase [51521] (5 proteins)

Proteins:

1. 6-phospho-beta-D-galactosidase, PGAL [51526] (1 species)

   • Species Lactococcus lactis [TaxId:1358] [51527] (4 PDB entries)

2. Beta-glucosidase A [51528] (7 species)

   1. Species Archaeon Pyrococcus horikoshii [TaxId:53953] [141785] (1 PDB entry)
      Uniprot O58104 1-423

   2. Species Bacillus circulans, subsp. alkalophilus [TaxId:1397] [51530] (1 PDB entry)

   3. Species Bacillus polymyxa [TaxId:1406] [51529] (5 PDB entries)

   4. Species Streptomyces sp. [TaxId:1931] [82248] (2 PDB entries)

   5. Species Thermotoga maritima [TaxId:2336] [89475] (23 PDB entries)
      Uniprot Q08638

   6. Species Thermus nonproteolyticus [TaxId:116039] [89477] (1 PDB entry)

   7. Species Thermus thermophilus [TaxId:274] [89476] (1 PDB entry)

3. beta-Glycosidase [51531] (2 species)

   1. Species Archaeon Sulfolobus solfataricus [TaxId:2287] [51532] (9 PDB entries)
      Uniprot P22498

   2. Species Archaeon Thermosphaera aggregans [TaxId:54254] [51533] (1 PDB entry)

4. Plant beta-glucosidase (myrosinase) [51522] (4 species)

   1. Species Creeping white clover (Trifolium repens) [TaxId:3899] [51524] (1 PDB entry)
      Cyanogenic beta-glucosidase

   2. Species Maize (Zea mays), zmglu1 [TaxId:4577] [51525] (9 PDB entries)
      Uniprot P49235

   3. Species Sorghum bicolor [TaxId:4558] [110351] (2 PDB entries)
      Uniprot Q41290

   4. Species White mustard (Sinapis alba) [TaxId:3728] [51523] (17 PDB entries)

5. Thioglucosidase [141786] (1 species)

   • Species Cabbage aphid (Brevicoryne brassicae) [TaxId:69196] [141787] (1 PDB entry)
     Uniprot Q95X01 3-464

More info for Family c.1.8.4: Family 1 of glycosyl hydrolase

Timeline for Family c.1.8.4: Family 1 of glycosyl hydrolase:

• Family c.1.8.4: Family 1 of glycosyl hydrolase first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.8.4: Family 1 of glycosyl hydrolase appears in SCOP 1.73
  
• Family c.1.8.4: Family 1 of glycosyl hydrolase appears in SCOPe 2.01
  
• Family c.1.8.4: Family 1 of glycosyl hydrolase appears in the current release, SCOPe 2.08