Lineage for Superfamily c.1.8: (Trans)glycosidases

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 473233Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 474052Superfamily c.1.8: (Trans)glycosidases [51445] (11 families) (S)


  1. 474053c.1.8.1: Amylase, catalytic domain [51446] (24 proteins)
    members of the family may contain various insert subdomains
    in alpha-amylases and closer relatives this domain is usually followed by a common all-beta domain
  2. 474407c.1.8.3: beta-glycanases [51487] (22 proteins)
    consist of a number of sequence families
  3. 474776c.1.8.4: Family 1 of glycosyl hydrolase [51521] (4 proteins)
  4. 474902c.1.8.5: Type II chitinase [51534] (14 proteins)
    glycosylase family 18
  5. 475055c.1.8.6: beta-N-acetylhexosaminidase catalytic domain [51550] (3 proteins)
    Glycosyl hydrolase family 20, GH20
  6. 475084c.1.8.7: Beta-D-glucan exohydrolase, N-terminal domain [51553] (1 protein)
  7. 475094c.1.8.8: 1,4-beta-N-acetylmuraminidase [63912] (3 proteins)
    Glycosyl hydrolase family 25; probably have evolved from a type II chitinase ancestor
    permutation of the common fold; strand 8 is antiparallel to the rest of the barrel
  8. 475105c.1.8.9: Bee venom hyaluronidase [69387] (1 protein)
    distorted barrel lacks the second strand
  9. 475111c.1.8.10: alpha-D-glucuronidase catalytic domain [82253] (1 protein)
    Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain
  10. 475132c.1.8.11: Putative alpha-L-fucosidase, catalytic domain [102079] (1 protein)
    glycosyl hydrolase family 29; contains additional beta-barrel with a topological similarity to the C-terminal domain of alpha amylases
  11. 475141c.1.8.12: Outer surface protein, N-terminal domain [110354] (1 protein)
    corresponds to the N-terminal part of Pfam 05913

More info for Superfamily c.1.8: (Trans)glycosidases

Timeline for Superfamily c.1.8: (Trans)glycosidases: