Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family) |
Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (15 proteins) Common fold covers whole protein structure |
Protein Aldose reductase (aldehyde reductase) [51436] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [51437] (53 PDB entries) |
Domain d1abna_: 1abn A: [28683] complexed with ndp; mutant |
Domain d1adsa_: 1ads A: [28671] complexed with nap |
Domain d1az1a_: 1az1 A: [28677] complexed with alr, nap; mutant |
Domain d1az2a_: 1az2 A: [28682] complexed with cit, nap; mutant |
Domain d1ef3a_: 1ef3 A: [28680] |
Domain d1ef3b_: 1ef3 B: [28681] complexed with fid, nap |
Domain d1el3a_: 1el3 A: [28672] complexed with i84, nap |
Domain d1ieia_: 1iei A: [71200] complexed with nap, zes |
Domain d1mara_: 1mar A: [28678] complexed with nap, zst |
Domain d1pwla_: 1pwl A: [95230] complexed with bfi, nap |
Domain d1pwma_: 1pwm A: [95231] complexed with cl, fid, nap |
Domain d1t40a_: 1t40 A: [106390] complexed with id5, nap |
Domain d1t41a_: 1t41 A: [106391] complexed with id5, nap |
Domain d1us0a_: 1us0 A: [99850] complexed with cit, ldt, ndp |
Domain d1x96a_: 1x96 A: [109524] complexed with cit, nap |
Domain d1x97a_: 1x97 A: [109525] complexed with fir, nap |
Domain d1x98a_: 1x98 A: [109526] complexed with cit, fis, nap |
Domain d1z3na1: 1z3n A:0-315 [124411] automatically matched to d1pwla_ complexed with 3na, ndp |
Domain d1z89a1: 1z89 A:0-315 [124695] automatically matched to d1pwla_ complexed with 62p, nap |
Domain d1z8aa1: 1z8a A:1-315 [124696] automatically matched to d1pwla_ complexed with 62p, nap |
Domain d2acqa_: 2acq A: [28675] complexed with g6p, nap |
Domain d2acra_: 2acr A: [28674] complexed with cac, nap |
Domain d2acsa_: 2acs A: [28673] complexed with cit, nap |
Domain d2acua_: 2acu A: [28676] complexed with cit, nap; mutant |
Domain d2alra_: 2alr A: [28679] different isozyme (?) |
Domain d2duxa1: 2dux A:1-315 [131753] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2duza1: 2duz A:1-315 [131754] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2dv0a1: 2dv0 A:2-315 [131755] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2f2ka1: 2f2k A:1-315 [132842] automatically matched to d1el3a_ complexed with ndp, tgg |
Domain d2fz8a1: 2fz8 A:1-315 [134421] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2fz9a1: 2fz9 A:1-315 [134422] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2fzba1: 2fzb A:1-315 [134423] automatically matched to d1pwla_ complexed with nap, tol |
Domain d2fzda1: 2fzd A:1-312 [134432] automatically matched to d1pwla_ complexed with nap, tol |
Domain d2hv5a1: 2hv5 A:2-315 [136783] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2hvna1: 2hvn A:1-315 [136814] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2hvoa1: 2hvo A:1-315 [136815] automatically matched to d1pwla_ complexed with nap, zst |
Domain d2i16a1: 2i16 A:2-314 [136978] automatically matched to d1pwla_ complexed with cit, ldt, ndp |
Domain d2i17a1: 2i17 A:2-314 [136979] automatically matched to d1pwla_ complexed with cit, ldt, ndp |
Domain d2ikga1: 2ikg A:0-315 [137488] automatically matched to d1pwla_ complexed with bto, nap |
Domain d2ikha1: 2ikh A:1-315 [137489] automatically matched to d1pwla_ complexed with lit, nap |
Domain d2ikia1: 2iki A:1-311 [137490] automatically matched to d1pwla_ complexed with 388, nap |
Domain d2ikja1: 2ikj A:1-315 [137491] automatically matched to d1pwla_ complexed with 393, nap |
Domain d2inea1: 2ine A:2-315 [137530] automatically matched to d1el3a_ complexed with nap, pac |
Domain d2inza1: 2inz A:1-315 [137535] automatically matched to d1el3a_ complexed with nap, ohp |
Domain d2ipwa1: 2ipw A:2-315 [137585] automatically matched to d1az1__ complexed with 2cl, nap; mutant |
Domain d2iq0a1: 2iq0 A:2-315 [137586] automatically matched to d1el3a_ complexed with 6na, nap |
Domain d2iqda1: 2iqd A:1-315 [137587] automatically matched to d1el3a_ complexed with lpa, nap |
Domain d2isfa1: 2isf A:2-315 [137602] automatically matched to d1az1__ complexed with nap, pac; mutant |
Domain d2j8ta1: 2j8t A:0-315 [138142] automatically matched to d1pwla_ complexed with flc, nap |
Domain d2nvca1: 2nvc A:1-315 [138628] automatically matched to d1pwla_ complexed with ita, nap |
Domain d2nvda1: 2nvd A:1-315 [138629] automatically matched to d1pwla_ complexed with itb, nap |
Domain d2peva1: 2pev A:0-315 [139669] automatically matched to d1pwla_ complexed with cit, cl, fid, ldt, ndp |
Domain d2pf8a1: 2pf8 A:0-315 [139670] automatically matched to d1pwla_ complexed with cit, cl, fid, ldt, ndp |
Domain d2pfha1: 2pfh A:0-313 [139671] automatically matched to d1pwla_ complexed with cit, cl, fid, ldt, ndp |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.1.7.1 Aldose reductase (aldehyde reductase):