Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (1 family) The phosphate moiety of substrate binds in the 'common' phosphate-binding site |
Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein) |
Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species) |
Chinese hamster (Cricetulus griseus) [TaxId:10029] [63902] (1 PDB entry) |
Domain d1jr1a1: 1jr1 A:17-112,A:233-514 [63241] Other proteins in same PDB: d1jr1a4 contains two CBS domains inserted into the common fold, residues 113-232 |
Domain d1jr1b1: 1jr1 B:11-112,B:233-514 [63244] Other proteins in same PDB: d1jr1a4 contains two CBS domains inserted into the common fold, residues 113-232 complexed with imp, k, moa |
Human (Homo sapiens), type I [TaxId:9606] [89456] (1 PDB entry) |
Domain d1jcna1: 1jcn A:10-111,A:232-499 [84160] Other proteins in same PDB: d1jcna4, d1jcnb4 contains two CBS domains inserted into the common fold, residues 111-231 |
Domain d1jcnb1: 1jcn B:10-111,B:232-499 [84163] Other proteins in same PDB: d1jcna4, d1jcnb4 contains two CBS domains inserted into the common fold, residues 111-231 complexed with cpr |
Human (Homo sapiens), type II [TaxId:9606] [51418] (3 PDB entries) |
Domain d1b3oa1: 1b3o A:10-109,A:232-499 [28640] Other proteins in same PDB: d1b3ob4 contains two CBS domains inserted into the common fold, residues 112-231 |
Domain d1b3ob1: 1b3o B:10-111,B:232-499 [28641] Other proteins in same PDB: d1b3ob4 contains two CBS domains inserted into the common fold, residues 112-231 complexed with cpr, sae |
Domain d1nf7a1: 1nf7 A:10-111,A:232-514 [91852] Other proteins in same PDB: d1nf7a4, d1nf7b4 |
Domain d1nf7b1: 1nf7 B:10-111,B:232-514 [91855] Other proteins in same PDB: d1nf7a4, d1nf7b4 complexed with k, myd, rvp |
Domain d1nfba1: 1nfb A:10-111,A:232-498 [91858] Other proteins in same PDB: d1nfba4, d1nfbb4 |
Domain d1nfbb1: 1nfb B:10-111,B:232-498 [91861] Other proteins in same PDB: d1nfba4, d1nfbb4 complexed with cpr, nad |
Lyme disease spirochete (Borrelia burgdorferi) [TaxId:139] [51415] (1 PDB entry) |
Domain d1eepa_: 1eep A: [28636] |
Domain d1eepb_: 1eep B: [28637] complexed with so4 |
Pyrococcus horikoshii [TaxId:53953] [159379] (1 PDB entry) Uniprot O58045 3-96,207-480 |
Domain d2cu0a1: 2cu0 A:3-96,A:207-480 [146425] disordered CBS domain is cut out complexed with xmp |
Streptococcus pyogenes [TaxId:1314] [51416] (1 PDB entry) |
Domain d1zfja1: 1zfj A:2-94,A:221-492 [28638] Other proteins in same PDB: d1zfja4 contains two CBS domains inserted into the common fold complexed with imp |
Thermotoga maritima [TaxId:2336] [159378] (1 PDB entry) Uniprot Q9X168 1-85,213-457 |
Domain d1vrda1: 1vrd A:1-85,A:213-457 [145788] disordered CBS domain is cut out |
Tritrichomonas foetus [TaxId:5724] [51417] (9 PDB entries) |
Domain d1ak5a1: 1ak5 A:2-101,A:222-483 [28639] there two CBS domains in the disordered region 102-221 complexed with so4 |
Domain d1lrta1: 1lrt A:2-100,A:231-485 [84685] there are two CBS domains in the disordered region 101-230 |
Domain d1lrtb1: 1lrt B:2-100,B:231-485 [84686] there are two CBS domains in the disordered region 101-230 |
Domain d1lrtc1: 1lrt C:2-100,C:231-485 [84687] there are two CBS domains in the disordered region 101-230 |
Domain d1lrtd1: 1lrt D:2-100,D:231-485 [84688] there are two CBS domains in the disordered region 101-230 complexed with bog, imp, k, tad, trs |
Domain d1me7a1: 1me7 A:2-107,A:220-492 [79027] there two CBS domains in the disordered region 108-219 complexed with k, moa, na, rvp |
Domain d1me8a1: 1me8 A:2-101,A:222-492 [79028] there two CBS domains in the disordered region 102-221 complexed with cso, k, na, rvp |
Domain d1me9a1: 1me9 A:2-101,A:222-483 [91249] there two CBS domains in the disordered region 102-221 complexed with imp, k |
Domain d1meha1: 1meh A:2-106,A:222-483 [91250] there two CBS domains in the disordered region 107-221 complexed with imp, k, moa |
Domain d1meia1: 1mei A:2-101,A:222-483 [91251] there two CBS domains in the disordered region 102-221 complexed with k, moa, xmp |
Domain d1mewa1: 1mew A:2-101,A:222-483 [91256] there two CBS domains in the disordered region 102-221 complexed with k, nad, xmp |
Domain d1pvna1: 1pvn A:2-99,A:231-494 [88312] there are two CBS domains in the disordered region 100-230 |
Domain d1pvnb1: 1pvn B:2-99,B:231-494 [88313] there are two CBS domains in the disordered region 100-230 |
Domain d1pvnc1: 1pvn C:2-99,C:231-494 [88314] there are two CBS domains in the disordered region 100-230 |
Domain d1pvnd1: 1pvn D:2-99,D:231-494 [88315] there are two CBS domains in the disordered region 100-230 complexed with k, mzp, trs |
Timeline for Protein Inosine monophosphate dehydrogenase (IMPDH) from c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH):