Lineage for Protein: Dihydroorotate dehydrogenase

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 814174Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 814735Superfamily c.1.4: FMN-linked oxidoreductases [51395] (1 family) (S)
  5. 814736Family c.1.4.1: FMN-linked oxidoreductases [51396] (18 proteins)
  6. 814782Protein Dihydroorotate dehydrogenase [51397] (7 species)

Species:

  1. 814783Escherichia coli [TaxId:562] [82239] (1 PDB entry)
  2. 814788Human (Homo sapiens) [TaxId:9606] [51400] (11 PDB entries)
    1. Domain for 1d3g:
    2. Domain for 1d3h:
    3. Domain for 2b0m:
    4. Domain for 2bxv:
    5. Domain for 2fpt:
    6. Domain for 2fpv:
    7. Domain for 2fpy:
    8. Domain for 2fqi:
    9. Domain for 2prh:
    10. Domain for 2prl:
    11. Domain for 2prm:
  3. 814800Lactococcus lactis, isozyme A [TaxId:1358] [51398] (11 PDB entries)
    1. Domains for 1dor:
      1. 814811Domain d1dora_: 1dor A: [28595]
      2. 814812Domain d1dorb_: 1dor B: [28596]
        complexed with fmn
    2. Domains for 1jqv:
      1. 814815Domain d1jqva_: 1jqv A: [90900]
      2. 814816Domain d1jqvb_: 1jqv B: [90901]
        complexed with acy, fmn, mg, oro; mutant
    3. Domains for 1jqx:
      1. 814803Domain d1jqxa_: 1jqx A: [90902]
      2. 814804Domain d1jqxb_: 1jqx B: [90903]
        complexed with fmn, gol, mg, oro; mutant
    4. Domains for 1jrb:
      1. 814813Domain d1jrba_: 1jrb A: [90904]
      2. 814814Domain d1jrbb_: 1jrb B: [90905]
        complexed with fmn, oro; mutant
    5. Domains for 1jrc:
      1. 814805Domain d1jrca_: 1jrc A: [90906]
      2. 814806Domain d1jrcb_: 1jrc B: [90907]
        complexed with fmn, oro; mutant
    6. Domains for 1jub:
      1. 814801Domain d1juba_: 1jub A: [90908]
      2. 814802Domain d1jubb_: 1jub B: [90909]
        complexed with fmn, gol, mg; mutant
    7. Domains for 1jue:
      1. 814807Domain d1juea_: 1jue A: [90910]
      2. 814808Domain d1jueb_: 1jue B: [90911]
        complexed with acy, fmn, gol, mg
    8. Domains for 1ovd:
      1. 814819Domain d1ovda_: 1ovd A: [93593]
      2. 814820Domain d1ovdb_: 1ovd B: [93594]
        complexed with fmn, gol, mg, oro; mutant
    9. Domains for 2bsl:
      1. 814821Domain d2bsla1: 2bsl A:1-311 [129095]
        automatically matched to d1dora_
        complexed with act, dhb, fmn, gol, mg
      2. 814822Domain d2bslb1: 2bsl B:1-311 [129096]
        automatically matched to d1dora_
        complexed with act, dhb, fmn, gol, mg
    10. Domains for 2bx7:
      1. 814817Domain d2bx7a1: 2bx7 A:1-311 [129395]
        automatically matched to d1dora_
        complexed with 34d, act, fmn, gol, mg
      2. 814818Domain d2bx7b1: 2bx7 B:1-311 [129396]
        automatically matched to d1dora_
        complexed with 34d, act, fmn, gol, mg
    11. Domains for 2dor:
      1. 814809Domain d2dora_: 2dor A: [28593]
      2. 814810Domain d2dorb_: 2dor B: [28594]
        complexed with fmn, oro
  4. 814823Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
    PyrD subunit
    1. Domain for 1ep1:
    2. Domain for 1ep2:
    3. Domain for 1ep3:
  5. 814827Plasmodium falciparum [TaxId:5833] [141759] (1 PDB entry)
    Uniprot Q08210 158-566
    homolog, mitochonrial
  6. 814829Rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
    1. Domains for 1uum:
      1. 814830Domain d1uuma_: 1uum A: [100010]
      2. 814831Domain d1uumb_: 1uum B: [100011]
        complexed with afi, bog, fmn, oro
    2. Domain for 1uuo:
  7. 814833Trypanosoma brucei [TaxId:5691] [141758] (1 PDB entry)
    Uniprot Q57U83 2-313

More info for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases

Timeline for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases: