SCOP 1.67: Protein: Dihydroorotate dehydrogenase

Lineage for Protein: Dihydroorotate dehydrogenase

Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.4: FMN-linked oxidoreductases [51395] (1 family)
Family c.1.4.1: FMN-linked oxidoreductases [51396] (15 proteins)
Protein Dihydroorotate dehydrogenase [51397] (5 species)

Species:

Escherichia coli [TaxId:562] [82239] (1 PDB entry)
- Domains for 1f76:
  1. Domain d1f76a_: 1f76 A: [76160]
  2. Domain d1f76b_: 1f76 B: [76161]
  3. Domain d1f76d_: 1f76 D: [76162]
  4. Domain d1f76e_: 1f76 E: [76163]
    complexed with fmn, fmt, mse, oro
Human (Homo sapiens) [TaxId:9606] [51400] (2 PDB entries)
1. Domain for 1d3g:
  - Domain d1d3ga_: 1d3g A: [28600]
    complexed with act, bre, ddq, fmn, oro, so4
2. Domain for 1d3h:
  - Domain d1d3ha_: 1d3h A: [28601]
    complexed with a26, act, fmn, oro, so4
Lactococcus lactis, isozyme A [TaxId:1358] [51398] (9 PDB entries)
1. Domains for 1dor:
  1. Domain d1dora_: 1dor A: [28595]
  2. Domain d1dorb_: 1dor B: [28596]
    complexed with fmn
2. Domains for 1jqv:
  1. Domain d1jqva_: 1jqv A: [90900]
  2. Domain d1jqvb_: 1jqv B: [90901]
    complexed with acy, fmn, mg, oro; mutant
3. Domains for 1jqx:
  1. Domain d1jqxa_: 1jqx A: [90902]
  2. Domain d1jqxb_: 1jqx B: [90903]
    complexed with fmn, gol, mg, oro; mutant
4. Domains for 1jrb:
  1. Domain d1jrba_: 1jrb A: [90904]
  2. Domain d1jrbb_: 1jrb B: [90905]
    complexed with fmn, oro; mutant
5. Domains for 1jrc:
  1. Domain d1jrca_: 1jrc A: [90906]
  2. Domain d1jrcb_: 1jrc B: [90907]
    complexed with fmn, oro; mutant
6. Domains for 1jub:
  1. Domain d1juba_: 1jub A: [90908]
  2. Domain d1jubb_: 1jub B: [90909]
    complexed with fmn, gol, mg; mutant
7. Domains for 1jue:
  1. Domain d1juea_: 1jue A: [90910]
  2. Domain d1jueb_: 1jue B: [90911]
    complexed with acy, fmn, gol, mg
8. Domains for 1ovd:
  1. Domain d1ovda_: 1ovd A: [93593]
  2. Domain d1ovdb_: 1ovd B: [93594]
    complexed with fmn, gol, mg, oro; mutant
9. Domains for 2dor:
  1. Domain d2dora_: 2dor A: [28593]
  2. Domain d2dorb_: 2dor B: [28594]
    complexed with fmn, oro
Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
PyrD subunit
1. Domain for 1ep1:
  - Domain d1ep1a_: 1ep1 A: [28598]
    Other proteins in same PDB: d1ep1b1, d1ep1b2
    complexed with fad, fes, fmn
2. Domain for 1ep2:
  - Domain d1ep2a_: 1ep2 A: [28599]
    Other proteins in same PDB: d1ep2b1, d1ep2b2
    complexed with fad, fes, fmn, oro
3. Domain for 1ep3:
  - Domain d1ep3a_: 1ep3 A: [28597]
    Other proteins in same PDB: d1ep3b1, d1ep3b2
    complexed with fad, fes, fmn
Rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
1. Domains for 1uum:
  1. Domain d1uuma_: 1uum A: [100010]
  2. Domain d1uumb_: 1uum B: [100011]
    complexed with afi, bog, fmn, oro
2. Domain for 1uuo:
  - Domain d1uuoa_: 1uuo A: [100014]
    complexed with brf, fmn, na, ni, oro

More info for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases

Timeline for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases:

Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases first appeared (with stable ids) in SCOP 1.55
Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases appears in SCOP 1.65
Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases appears in SCOP 1.69
Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases appears in the current release, SCOPe 2.08