Lineage for Family c.1.4.1: FMN-linked oxidoreductases

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2089714Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2091323Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2091324Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

Proteins:

  1. 2091325(S)-3-O-geranylgeranylglyceryl phosphate synthase [141765] (1 species)
  2. 209133112-oxophytodienoate reductase (OPR, OYE homolog) [63896] (3 species)
    1. 2091332Species Thale cress (Arabidopsis thaliana), OPR1 [TaxId:3702] [102040] (1 PDB entry)
      At1G76680
    2. 2091334Species Thale cress (Arabidopsis thaliana), OPR3 [TaxId:3702] [102041] (2 PDB entries)
    3. 2091339Species Tomato (Lycopersicon esculentum), OPR1 [TaxId:4081] [63897] (4 PDB entries)
  3. 20913482,4-dienoyl-CoA reductase, N-terminal domain [102042] (1 species)
  4. 2091351Alpha subunit of glutamate synthase, central and FMN domains [69381] (2 species)
    Central domain (residues 423-780) may be a rudiment form of the FMN domain
    1. 2091352Species Azospirillum brasilense [TaxId:192] [69382] (2 PDB entries)
    2. 2091361Species Synechocystis sp. [TaxId:1143] [75055] (5 PDB entries)
  5. 2091369Dihydroorotate dehydrogenase [51397] (8 species)
    1. 2091370Species Escherichia coli [TaxId:562] [82239] (1 PDB entry)
    2. 2091375Species Human (Homo sapiens) [TaxId:9606] [51400] (43 PDB entries)
    3. 2091419Species Lactococcus lactis, isozyme A [TaxId:1358] [51398] (9 PDB entries)
    4. 2091438Species Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
      PyrD subunit
    5. 2091442Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141759] (1 PDB entry)
      Uniprot Q08210 158-566
      homolog, mitochonrial
    6. 2091444Species Norway rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
    7. 2091448Species Trypanosoma cruzi [TaxId:353153] [254868] (49 PDB entries)
    8. 2091547Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [141758] (1 PDB entry)
      Uniprot Q57U83 2-313
  6. 2091549Dihydropyrimidine dehydrogenase, domain 4 [51410] (1 species)
  7. 2091571Flavocytochrome b2, C-terminal domain [51408] (1 species)
  8. 2091595Glycolate oxidase [51404] (1 species)
  9. 2091602Hydroxyacid oxidase [141761] (1 species)
  10. 2091605Isopentenyl-diphosphate delta-isomerase [89454] (3 species)
    1. 2091606Species Bacillus subtilis [TaxId:1423] [89455] (2 PDB entries)
    2. 2091611Species Thermus thermophilus HB8 [TaxId:300852] [159377] (1 PDB entry)
    3. 2091616Species Thermus thermophilus [TaxId:274] [141760] (1 PDB entry)
      Uniprot Q53W52 23-332
  11. 2091619Membrane-associated (S)-mandelate dehydrogenase [63898] (1 species)
  12. 2091624Morphinone reductase [75053] (1 species)
  13. 2091629NADPH dehydrogenase NamA [141763] (1 species)
    OYE homolog
  14. 2091639Old yellow enzyme (OYE) [51401] (2 species)
    1. 2091640Species Lager yeast (Saccharomyces pastorianus) [TaxId:27292] [51402] (20 PDB entries)
    2. 2091661Species Yeast (Candida albicans) [TaxId:5476] [51403] (2 PDB entries)
  15. 2091664PcrB protein homolog YerE [102046] (2 species)
    provisional classification; it is not known whether this protein binds FMN or not
    1. 2091665Species Bacillus subtilis [TaxId:1423] [102047] (5 PDB entries)
    2. 2091676Species Staphylococcus aureus [TaxId:418127] [194170] (2 PDB entries)
  16. 2091681Pentaerythritol tetranirate reductase [63900] (1 species)
  17. 2091713Putative flavin oxidoreducatase TM0096 [102044] (1 species)
    Dihydrouridine synthase (Dus) homologue; contains extra C-terminal alpha-helical domain
  18. 2091716Trimethylamine dehydrogenase, N-terminal domain [51406] (1 species)
    two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold
  19. 2091728automated matches [190228] (18 species)
    not a true protein
    1. 2091729Species Geobacillus kaustophilus [TaxId:235909] [257133] (2 PDB entries)
    2. 2091734Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)
    3. 2091743Species Kluyveromyces marxianus [TaxId:4911] [311442] (2 PDB entries)
    4. 2091752Species Lactococcus lactis [TaxId:1358] [186992] (3 PDB entries)
    5. 2091759Species Lactococcus lactis [TaxId:1360] [338684] (1 PDB entry)
    6. 2091762Species Leishmania braziliensis [TaxId:5660] [272759] (1 PDB entry)
    7. 2091765Species Leishmania donovani [TaxId:5661] [188354] (1 PDB entry)
    8. 2091770Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)
    9. 2091777Species Leishmania major [TaxId:5664] [255853] (6 PDB entries)
    10. 2091790Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [256645] (7 PDB entries)
    11. 2091802Species Norway rat (Rattus norvegicus) [TaxId:10116] [195883] (2 PDB entries)
    12. 2091807Species Plasmodium falciparum [TaxId:36329] [189697] (5 PDB entries)
    13. 2091813Species Pseudomonas putida [TaxId:303] [225091] (4 PDB entries)
    14. 2091818Species Solanum lycopersicum [TaxId:4081] [187823] (5 PDB entries)
    15. 2091829Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [187180] (2 PDB entries)
    16. 2091833Species Thermus thermophilus [TaxId:274] [254915] (1 PDB entry)
    17. 2091838Species Trypanosoma cruzi [TaxId:353153] [324150] (2 PDB entries)
    18. 2091843Species Trypanosoma cruzi [TaxId:5693] [187324] (7 PDB entries)

More info for Family c.1.4.1: FMN-linked oxidoreductases

Timeline for Family c.1.4.1: FMN-linked oxidoreductases: