SCOP 1.65: Family c.1.4.1: FMN-linked oxidoreductases

Lineage for Family c.1.4.1: FMN-linked oxidoreductases

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (1 family)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (12 proteins)

Proteins:

1. 12-oxophytodienoate reductase 1 (OYE homolog) [63896] (1 species)

   • Species Tomato (Lycopersicon esculentum) [TaxId:4081] [63897] (3 PDB entries)

2. Alpha subunit of glutamate synthase, central and FMN domains [69381] (2 species)
   Central domain (residues 423-780) may be a rudiment form of the FMN domain

   1. Species Azospirillum brasilense [TaxId:192] [69382] (1 PDB entry)

   2. Species Synechocystis sp. [TaxId:1143] [75055] (5 PDB entries)

3. Dihydroorotate dehydrogenase [51397] (4 species)

   1. Species Escherichia coli [TaxId:562] [82239] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [51400] (2 PDB entries)

   3. Species Lactococcus lactis, isozyme A [TaxId:1358] [51398] (2 PDB entries)

   4. Species Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
      PyrD subunit

4. Dihydropyrimidine dehydrogenase, domain 4 [51410] (1 species)

   • Species Pig (Sus scrofa) [TaxId:9823] [51411] (5 PDB entries)

5. Flavocytochrome b2, C-terminal domain [51408] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51409] (7 PDB entries)
     N-terminal domain homologous to cytochrome b5

6. Glycolate oxidase [51404] (1 species)

   • Species Spinach (Spinacia oleracea) [TaxId:3562] [51405] (4 PDB entries)

7. Isopentenyl-diphosphate delta-isomerase [89454] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [89455] (2 PDB entries)

8. Membrane-associated (S)-mandelate dehydrogenase [63898] (1 species)

   • Species Pseudomonas putida [TaxId:303] [63899] (1 PDB entry)

9. Morphinone reductase [75053] (1 species)

   • Species Pseudomonas putida [TaxId:303] [75054] (1 PDB entry)

10. Old yellow enzyme (OYE) [51401] (2 species)

    1. Species Brewer's yeast (Saccharomyces carlsbergensis) [51402] (5 PDB entries)

    2. Species Yeast (Candida albicans) [TaxId:5476] [51403] (2 PDB entries)

11. Pentaerythritol tetranirate reductase [63900] (1 species)

    • Species Enterobacter cloacae [TaxId:550] [63901] (9 PDB entries)

12. Trimethylamine dehydrogenase, N-terminal domain [51406] (1 species)
    two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold

    • Species Methylophilus methylotrophus, w3a1 [TaxId:17] [51407] (5 PDB entries)

More info for Family c.1.4.1: FMN-linked oxidoreductases

Timeline for Family c.1.4.1: FMN-linked oxidoreductases:

• Family c.1.4.1: FMN-linked oxidoreductases first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.4.1: FMN-linked oxidoreductases appears in SCOP 1.63
  
• Family c.1.4.1: FMN-linked oxidoreductases appears in SCOP 1.67
  
• Family c.1.4.1: FMN-linked oxidoreductases appears in the current release, SCOPe 2.08